HYDROXYUREA

作品数:26被引量:24H指数:3
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相关领域:医药卫生生物学更多>>
相关作者:谢恒月钱若兰吴娇娇吴国民叶秀菊更多>>
相关机构:中国科学院上海生命科学研究院浙江省台州医院华东理工大学更多>>
相关期刊:《Open Journal of Genetics》《Open Journal of Veterinary Medicine》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金:国家自然科学基金更多>>
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Hydroxyurea-related ileocecal region ulcers as a rare complication:A case report
《World Journal of Clinical Cases》2025年第6期24-29,共6页Wen-Jin Yuan Yi-Juan Zheng Bing-Rong Zhang Yi-Jie Lin You Li Yan-Yan Qiu Xue-Ping Yu 
Supported by National Natural Science Foundation of China,No.82370604;Major Science and Technology innovation Project of Fujian Province,No.2023Y9269;Natural Science Foundation of Fujian Province,China,No.2023J01239.
BACKGROUND Hydroxyurea,an antimetabolite,is frequently prescribed for various hemato-logical disorders,and its common side effects include gastrointestinal problems,cutaneous or mucosal lesions and pyrexia/fever.CASE ...
关键词:HYDROXYUREA ULCER Abdominal pain THROMBOCYTHEMIA COLONOSCOPY Case report 
Sickle Crisis Precipitated by Pneumonia: A Diagnostic and Therapeutic Challenge
《Journal of Biosciences and Medicines》2025年第1期255-263,共9页David Fernando Ortiz-Pérez Luisa María Petro-Noriega Margarita Rosa Burgos-Peña Marlon José Rosado-Mendoza Santiago Sánchez-Rojas Cristina De Jesús Portillo-Monterrosa Daniel de Jesús González-Villarreal Juan Pablo de la Ossa Díaz John Sebastián Osorio-Muñoz Manuel Esteban Ortiz Pérez Ana María García-Suárez 
Sickle cell anemia (SCA) is a prevalent genetic disorder primarily affecting individuals of African descent and populations in malaria-endemic regions, with significant global public health implications. Sickle cell c...
关键词:Sickle Cell Anemia Sickle Cell Crisis Pain Management PNEUMONIA HYDROXYUREA 
Influence of Hemoglobin S Haplotypes on the Responses to Hydroxyurea Treatment in Children with Sickle Cell Disease in Abidjan, Côte d’Ivoire
《Open Journal of Genetics》2024年第1期1-12,共12页Mireille Aye-Yayo Vincent Yapo Boidy Kouakou Missa Louis Adjé Adia Eusèbe Adjambri Ebah Hermance Kassi Taïratou Kamagate Duni Sawadogo 
Background: In Côte d’Ivoire so far, the circulating haplotypes have been inferred on the phenotypic profiling of SCD patients. The impact of the circulating haplotypes on the use of Hydroxyurea has not been assessed...
关键词:Sickle Cell Disease CHILDREN HAPLOTYPE HYDROXYUREA Côte d’Ivoire 
Review on Hydroxyurea Usage in Young Children with Sickle Cell Disease: Examining Hemoglobin Induction, Potential Benefits, Responses, Safety, and Effectiveness
《International Journal of Clinical Medicine》2024年第1期1-18,共18页Maiko Charles Mkwambe Youping Deng Dongchi Zhao 
Sickle cell disease (SCD) is a prevalent condition, particularly in the countries of sub-Saharan Africa, where the presence of specific genes associated with Malaria contributes to its high prevalence. Patients with s...
关键词:EFFECTIVENESS HYDROXYUREA Sickle Cell Disease Sickle Cell Anemia Minimally Effective Dose Maximum Tolerated Dose 
Recurrent melanonychia on multiple nails and alopecia induced by hydroxyurea therapy
《Chinese Medical Journal》2022年第17期2142-2142,共1页Yifang Sun Zhenlin Xu Xiaolan Ding 
To the Editor:A 65-year-old Asian woman presented with pigmented nails for'5 years.She had a 9-year history of primarythrombocytosis andwas treatedwith hydroxyurea in varyingdoses rangingfrom500 to1000mgdaily5 years a...
关键词:BANDS doses PIGMENTED 
Essential thrombocythemia with non-ST-segment elevation myocardial infarction as the first manifestation:A case report
《World Journal of Clinical Cases》2022年第21期7422-7428,共7页Zhi-Ming Wang Wei-Hai Chen Yan-Ming Wu Lin-Quan Wang Fu-Long Ye Ren-Lin Yin 
BACKGROUND We report a case of essential thrombocythemia(ET)in a 44-year-old male who exhibited non-ST-segment-elevation myocardial infarction(NSTEMI)as the first manifestation without known cardiovascular risk factor...
关键词:Essential thrombocythemia Non-ST-segment-elevation myocardial infarction Percutaneous coronary intervention HYDROXYUREA Case report 
IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia
《Frontiers of Medicine》2022年第3期403-415,共13页Xiao Huang Tingting Ma Yongmei Zhu Bo Jiao Shanhe Yu Kankan Wang Jian-Qing Mi Ruibao Ren 
supported by the National Key Research and Development Program(No.2016YFC0902800 to Ruibao Ren);the Key Project of National Natural Science Foundation of China(No.81530006 to Ruibao Ren);Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research(No.2019CXJQ01 to Ruibao Ren);National Natural Science Foundation of China(No.81870112 to Ruibao Ren).
The morbidity and mortality of myeloproliferative neoplasms(MPNs)are primarily caused by arterial and venous complications,progression to myelofibrosis,and transformation to acute leukemia.However,identifying molecula...
关键词:myeloproliferative neoplasms IRF4 IRF8 HYDROXYUREA essential thrombocythemia 
Eighty-year-old man with rare chronic neutrophilic leukemia caused by CSF3R T618I mutation:A case report and review of literature
《World Journal of Clinical Cases》2020年第24期6337-6345,共9页Ya-Ping Li Na Chen Xian-Mei Ye Yong-Shou Xia 
BACKGROUNDChronic neutrophilic leukemia (CNL) is a rare bone marrow proliferative tumorand a heterogeneous disorder. In 2016, the World Health Organization includedactivating mutations in the CSF3R gene as one of the ...
关键词:Chronic neutrophilic leukemia LEUKEMIA Hyperplasia of interstitial neutrophil system CSF3R Case report HYDROXYUREA ALLOPURINOL 
Acute lymphoblastic leukemia in a β-thalassemia intermedia child: A case report
《World Journal of Clinical Pediatrics》2020年第1期1-6,共6页Laila M Sherief Esmael Goneim Naglaa M Kamal Amr Ibraheim Fuad Alsofiani Abdulraouf Alawur 
BACKGROUNDβ-thalassemia intermedia(βTI)is one of the hemoglobinopathies.It constitutes 10%ofβ-thalassemia cases yet being associated with a better quality of life thanβ-thalassemia major(βTM).CASE SUMMARY We rece...
关键词:Acute lymphoblastic leukemia Thalassemia intermedia Children MALIGNANCIES Iron overload HYDROXYUREA Case report 
Hydroxyurea-induced cutaneous squamous cell carcinoma: A case report
《World Journal of Clinical Cases》2019年第23期4091-4097,共7页Yan Xu Jian Liu 
BACKGROUND Hydroxyurea(HU)is a non-alkylating antineoplastic agent that is active in the Sphase of the cell cycle and inhibits the enzyme ribonucleoside reductase.HU is currently used to treat leukemia,sickle cell ane...
关键词:HYDROXYUREA SQUAMOUS cell CARCINOMA PRIMARY MYELOFIBROSIS Case report 
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