ALLOPURINOL

作品数:24被引量:46H指数:5
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相关领域:医药卫生更多>>
相关作者:劳海燕朱佐江黄绪亮吴坤莹赵克森更多>>
相关机构:广州医学院第二附属医院温州医学院附属第一医院广东省人民医院中国人民解放军第一军医大学更多>>
相关期刊:《中国循证儿科杂志》《Journal of Traditional Chinese Medicine》《Advances in Generial Practice of Medicine》《Chinese Journal of Integrative Medicine》更多>>
相关基金:广东省科技计划工业攻关项目国家自然科学基金更多>>
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Combination of allopurinol with Dahuang Mudan Tang(大黄牡丹汤)significantly improve kidney function and alleviate oxidative stress and inflammation of chronic kidney disease stageⅠ-Ⅲpatients with hyperuricemia
《Journal of Traditional Chinese Medicine》2024年第1期182-187,共6页FANG Congcong ZHU Xiaoliang ZHANG Yongjian QI Huan ZHANG Yingjie 
Qinhuangdao Science and Technology Research and Development Plan:Clinical Study of Rhubarb and Peony Decoction in the Treatment of Chronic Kidney Disease Stage 1-3 Complicated with Hyperuricemia(202101A203)。
OBJECTIVE:To evaluate the effect of Dahuang Mudan Tang(大黄牡丹汤,DHMD)and allopurinol on the treatment of chronic kidney disease staged G1-G3b patients with hyperuricemia and to provide novel insights into the clinic...
关键词:ALLOPURINOL renal insufficiency chronic HYPERURICEMIA uric acid urine protein Rhubarb Peony decoction 
Pulmonary sarcoidosis:A novel sequelae of drug reaction with eosinophilia and systemic symptoms:A case report
《World Journal of Clinical Cases》2022年第35期13074-13080,共7页Yu-Qi Hu Chen-Yang Lv Ai Cui 
BACKGROUND Drug reaction with eosinophilia and systemic symptoms(DRESS)syndrome is an uncommon yet serious adverse drug hypersensitivity reaction with the presentations including rash,fever,lymphadenopathy,and interna...
关键词:Pulmonary sarcoidosis Drug reaction with eosinophilia and systemic symptoms Autoimmune sequelae ALLOPURINOL Case report 
Clinical Efficacy of Febuxostat Combined with Allopurinol in the Treatment of Hyperuricemia Patients
《外文科技期刊数据库(文摘版)医药卫生》2021年第6期006-007,共4页ZHU Mengni HOU Lianhua 
Objective: the experiment will focus on the implementation of drug therapy for patients with hyperuricemia. The research focuses on the analysis of the application results of febuxostat combined with allopurinol. Meth...
关键词:FEBUXOSTAT ALLOPURINOL HYPERURICEMIA clinical curative effect 
别嘌醇(allopurinol)
《中国合理用药探索》2021年第6期9-9,共1页
【药理作用】本药是抑制尿酸合成的药物。别嘌醇及其代谢产物氧嘌呤醇均能抑制黄嘌呤氧化酶,阻止次黄嘌呤和黄嘌呤代谢为尿酸,从而减少尿酸的生成。【体内过程】本药口服后在胃肠道内吸收完全,2~6 h血药浓度可达峰值,t 1/2为28 h,与氧...
关键词:尿酸性肾病 排出时间 体内过程 痛风石 高尿酸血症 肾功能不全 黄嘌呤氧化酶 别嘌醇 
Eighty-year-old man with rare chronic neutrophilic leukemia caused by CSF3R T618I mutation:A case report and review of literature
《World Journal of Clinical Cases》2020年第24期6337-6345,共9页Ya-Ping Li Na Chen Xian-Mei Ye Yong-Shou Xia 
BACKGROUNDChronic neutrophilic leukemia (CNL) is a rare bone marrow proliferative tumorand a heterogeneous disorder. In 2016, the World Health Organization includedactivating mutations in the CSF3R gene as one of the ...
关键词:Chronic neutrophilic leukemia LEUKEMIA Hyperplasia of interstitial neutrophil system CSF3R Case report HYDROXYUREA ALLOPURINOL 
Cardiovascular events in hyperuricemia population and a cardiovascular benefit-risk assessment of urate-lowering therapies:a systematic review and meta-analysis被引量:7
《Chinese Medical Journal》2020年第8期982-993,共12页Li Zhao Ling Cao Tian-Yi Zhao Xue Yang Xiao-Xia Zhu He-Jian Zou Wei-Guo Wan Yu Xue 
This work was supported by a grant from the National Natural Science Foundation of China(No.81601396)。
Background:Hyperuricemia and gout have become public health concerns;many important guidelines have recommended xanthine oxidase inhibitors(XOIs)as the first-line urate-lowering therapies(ULTs)to treat chronic gout wi...
关键词:HYPERURICEMIA GOUT Cardiovascular event FEBUXOSTAT ALLOPURINOL 
Therapeutic potential of ethyl acetate fraction of Tephrosia purpurea Linn.leaves in a rat model of gout
《Journal of Integrative Medicine》2019年第6期455-460,共6页Sonali S.Nipate Pramila S.Yelmar 
Objective: The present study is to determine the potential treatment effects of ethyl acetate fraction of Tephrosia purpurea Linn. leaves(EATP) against gout.Methods: Gout in experimental rats was induced with potassiu...
关键词:GOUT Potassium oxonate Ethyl acetate fraction Tephrosia purpurea Linn.leaves Uric acid deposition Radiological evaluation ALLOPURINOL 
Allopurinol-induced DRESS syndrome in the elderly: an exceptional form of iatrogenesis
《Advances in Generial Practice of Medicine》2019年第1期5-8,共4页Salem Bouomrani Fatma Rekik Safa Trabelsi Souad Yahyaoui Nesrine Belgacem 
Introduction: The Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a very rare iatrogenic accident that is characterized by its difficult diagnosis due to its clinical latency and heterogeneous cl...
关键词:DRESS SYNDROME iatrogenesis ALLOPURINOL CUTANEOUS drug reaction ELDERLY 
Efficacy and Safety of Febuxost at in the Treatment of Chronic Kidney Disease with Hyperuricemia: A Meta- Analysis
《临床医学工程》2017年第S1期7-12,共6页Jingyun Ou Bin Yan Shenling Huang Mingming Ma Jun Ke Hongwei Hu Sibo Huang Xiangnan Dong Aiyun Cha Zuhui Chen Yu Mong Fanna Liu W.Pommer Chen Yun Yongpin Lu Shufei Zeng Lianghong Yin B.Hocher 
Guangzhou Development Zone entrepreneurship leading talent project(2017-L153);Guangdong University blood purification technology and Engineering Research Center(GCZX-A1104);Guangzhou entrepreneurial leader talent/LCY201215;Guangdong Provincial Center for clinical engineering of blood purification(507204531040);Guangdong Obers Blood Purification Academician Work station(2013B090400004)
Background Febuxostat and allopurinol have different pharmacological mechanisms,the efficacy of febuxostat in chronic kidney disease complicated with hyperuricemia remains controversial.A meta-analysis and systemic re...
关键词:FEBUXOSTAT Chronic kidney disease HYPERURICEMIA ALLOPURINOL META-ANALYSIS 
Any link of gout disease control among hypertensive patients and onset of end-stage renal disease?Results from a population-based study被引量:2
《World Journal of Nephrology》2017年第3期132-142,共11页Sylvie Perreault Javier Nuevo Scott Baumgartner Robert Morlock 
funded by AstraZeneca
AIM To determine the impact of allopurinol non-adherence as a proxy for uncontrolled disease on primary prevention of end-stage renal disease(ESRD).METHODS A cohort of 2752 patients with gout diagnosis was reconstruct...
关键词:ALLOPURINOL End-stage renal disease GOUT HYPERURICEMIA Medication adherence Serum uric acid 
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