Qinhuangdao Science and Technology Research and Development Plan:Clinical Study of Rhubarb and Peony Decoction in the Treatment of Chronic Kidney Disease Stage 1-3 Complicated with Hyperuricemia(202101A203)。
OBJECTIVE:To evaluate the effect of Dahuang Mudan Tang(大黄牡丹汤,DHMD)and allopurinol on the treatment of chronic kidney disease staged G1-G3b patients with hyperuricemia and to provide novel insights into the clinic...
BACKGROUND Drug reaction with eosinophilia and systemic symptoms(DRESS)syndrome is an uncommon yet serious adverse drug hypersensitivity reaction with the presentations including rash,fever,lymphadenopathy,and interna...
Objective: the experiment will focus on the implementation of drug therapy for patients with hyperuricemia. The research focuses on the analysis of the application results of febuxostat combined with allopurinol. Meth...
BACKGROUNDChronic neutrophilic leukemia (CNL) is a rare bone marrow proliferative tumorand a heterogeneous disorder. In 2016, the World Health Organization includedactivating mutations in the CSF3R gene as one of the ...
This work was supported by a grant from the National Natural Science Foundation of China(No.81601396)。
Background:Hyperuricemia and gout have become public health concerns;many important guidelines have recommended xanthine oxidase inhibitors(XOIs)as the first-line urate-lowering therapies(ULTs)to treat chronic gout wi...
Objective: The present study is to determine the potential treatment effects of ethyl acetate fraction of Tephrosia purpurea Linn. leaves(EATP) against gout.Methods: Gout in experimental rats was induced with potassiu...
Introduction: The Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a very rare iatrogenic accident that is characterized by its difficult diagnosis due to its clinical latency and heterogeneous cl...
Guangzhou Development Zone entrepreneurship leading talent project(2017-L153);Guangdong University blood purification technology and Engineering Research Center(GCZX-A1104);Guangzhou entrepreneurial leader talent/LCY201215;Guangdong Provincial Center for clinical engineering of blood purification(507204531040);Guangdong Obers Blood Purification Academician Work station(2013B090400004)
Background Febuxostat and allopurinol have different pharmacological mechanisms,the efficacy of febuxostat in chronic kidney disease complicated with hyperuricemia remains controversial.A meta-analysis and systemic re...
AIM To determine the impact of allopurinol non-adherence as a proxy for uncontrolled disease on primary prevention of end-stage renal disease(ESRD).METHODS A cohort of 2752 patients with gout diagnosis was reconstruct...