云南高校图书馆联盟文献共享服务平台- FEBUXOSTAT

FEBUXOSTAT: 作品数：28被引量：64H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：刘传飞王春辉武瑊郑志兵李松更多>>; 相关机构：沈阳药科大学南昌大学军事医学科学院中国药科大学更多>>; 相关期刊：《China Medical Abstracts(Internal Medicine)》《Journal of Chinese Pharmaceutical Sciences》《Journal of Analytical Sciences, Methods and Instrumentation》《Journal of Geriatric Cardiology》更多>>; 相关基金：国家自然科学基金北京市自然科学基金江西省自然科学基金国家重点基础研究发展计划更多>>

Green UHPLC Method for Simultaneous Determination of Febuxostat and Diclofenac in Pharmaceutical Dosage Form and Human Plasma: 《Journal of Analytical Sciences, Methods and Instrumentation》2021年第4期29-45,共17页Shimaa A. Mahmoud Amira M. El-Kosasy Fatma A. Fouad; Eco-friendly Ultra-high-performance liquid chromatography (UHPLC) with green aqueous-organic mobile phase was applied for the simultaneous determination of febuxostat (FEB) and diclofenac (DIC) with the composition of...; 关键词：FEBUXOSTAT DICLOFENAC Ultra-High-Performance Liquid Chromatography Eco-Scale Green Analytical Procedure Index Tools

Characteristic dysbiosis in gout and the impact of a uric acid-lowering treatment,febuxostat on the gut microbiota被引量：6: 《Journal of Genetics and Genomics》2021年第9期781-791,共11页Suxian Lin Tao Zhang Lingxiao Zhu Kun Pang Saisai Lu Xin Liao Senhong Ying Lixia Zhu Xin Xu Jinyu Wu Xiaobing Wang; the Project of Zhejiang Provincial Department of Education,China(Y202045471);the Project of Wenzhou Science and Technology,China(NO.Y2020205)。; Gut dysbiosis is suggested to play a critical role in the pathogenesis of gout.The aim of our study was to identify the characteristic dysbiosis of the gut microbiota in gout patients and the impact of a commonly used...; 关键词：GOUT Gut microbiota FEBUXOSTAT METABOLISM Gene sequencing

Cardiovascular events in hyperuricemia population and a cardiovascular benefit-risk assessment of urate-lowering therapies:a systematic review and meta-analysis被引量：7: 《Chinese Medical Journal》2020年第8期982-993,共12页Li Zhao Ling Cao Tian-Yi Zhao Xue Yang Xiao-Xia Zhu He-Jian Zou Wei-Guo Wan Yu Xue; This work was supported by a grant from the National Natural Science Foundation of China(No.81601396)。; Background:Hyperuricemia and gout have become public health concerns;many important guidelines have recommended xanthine oxidase inhibitors(XOIs)as the first-line urate-lowering therapies(ULTs)to treat chronic gout wi...; 关键词：HYPERURICEMIA GOUT Cardiovascular event FEBUXOSTAT ALLOPURINOL

Effect of urate-lowering therapy with febuxostat on oxidative stress in hyperuricemic patients with chronic kidney disease stages 3-5: 《China Medical Abstracts(Internal Medicine)》2019年第4期225-226,共2页ZHANG Xiaoxiao; Objective To estimate the effect of urate-lowering therapy with febuxostat on oxidative stress in chronic kidney disease(CKD)stages 3-5 patients with hyperuricemia(HUA).Methods The study was a prospective cohort study...; 关键词：EFFECT urate-lowering disease

Effects of febuxostat on atrial remodeling in a rabbit model of atrial fibrillation induced by rapid atrial pacing被引量：2: 《Journal of Geriatric Cardiology》2019年第7期540-551,共12页Yong-Yan FAN Feng XU Chao ZHU Wen-Kun CHENG Jian LI Zhao-Liang SHAN Yang LI Yu-Tang WANG; supported by the Beijing Natural Science Foundation(Z141100002114050); Background Febuxostat,a novel nonpurine selective inhibitor of xanthine oxidase(XO),may be used in the prevention and management of atrial fibrillation(AF).The purpose of this study was to evaluate the effects of febu...; 关键词：ATRIAL FIBRILLATION ATRIAL remodeling FEBUXOSTAT Rapid ATRIAL PACING XANTHINE OXIDASE

Febuxostat对痛风伴高尿酸血症患者的血液流变学和血小板活化功能的影响被引量：6: 《基础医学与临床》2018年第11期1568-1571,共4页刘青员祁广东陈鑫; 目的探讨febuxostat(非布司他)对痛风伴高尿酸血症患者血液流变学及血小板活化功能的影响。方法选取滨海县人民医院2015年4月至2017年3月收治的痛风伴高尿酸血症患者68例,随机分为对照组(35例)(给予别嘌醇治疗)和观察组(33例)(给予febux...; 关键词：FEBUXOSTAT 别嘌醇高尿酸血症痛风血液流变学血小板活化功能

Perturbation of Quorum Sensing in <i>Pseudomonas aeruginosa</i>by Febuxostat被引量：1: 《Advances in Microbiology》2018年第8期650-664,共15页Hisham Abdel Monem Abbas Wafaa Ezz Elarab Soliman Moutaz Ahamed Shaldam; Quorum sensing is a signal-based communication system in bacteria. It is an attractive target because it regulates the production of virulence factors in Pseudomonas aeruginosa. As a result, interference with quorum s...; 关键词：FEBUXOSTAT Pseudomonas AERUGINOSA QUORUM Sensing Virulence Inhibition Molecular Docking

美国警告非布司他心脏相关性死亡风险: 《中国医药导刊》2018年第1期31-31,共1页美国FDA网站; 2017年11月15日,美国食品药品管理局(FDA)发布安全性警示公告称,一项安全性临床试验的初步结果表明,与别嘌醇相比,抗痛风药非布司他(febuxostat,商品名Uloric)可能增加心脏相关性死亡的风险。FDA在2009年批准该药物时,已要求非布司他的...; 关键词：美国食品药品管理局死亡风险相关性心脏 FEBUXOSTAT FDA批准抗痛风药武田制药公司

Efficacy and Safety of Febuxost at in the Treatment of Chronic Kidney Disease with Hyperuricemia: A Meta- Analysis: 《临床医学工程》2017年第S1期7-12,共6页Jingyun Ou Bin Yan Shenling Huang Mingming Ma Jun Ke Hongwei Hu Sibo Huang Xiangnan Dong Aiyun Cha Zuhui Chen Yu Mong Fanna Liu W.Pommer Chen Yun Yongpin Lu Shufei Zeng Lianghong Yin B.Hocher; Guangzhou Development Zone entrepreneurship leading talent project(2017-L153);Guangdong University blood purification technology and Engineering Research Center(GCZX-A1104);Guangzhou entrepreneurial leader talent/LCY201215;Guangdong Provincial Center for clinical engineering of blood purification(507204531040);Guangdong Obers Blood Purification Academician Work station(2013B090400004); Background Febuxostat and allopurinol have different pharmacological mechanisms,the efficacy of febuxostat in chronic kidney disease complicated with hyperuricemia remains controversial.A meta-analysis and systemic re...; 关键词：FEBUXOSTAT Chronic kidney disease HYPERURICEMIA ALLOPURINOL META-ANALYSIS

Preparation, optimization and in vitro–in vivo investigation for capsules of the choline salt of febuxostat: 《Asian Journal of Pharmaceutical Sciences》2016年第6期715-721,共7页Xuemei Han Wanpeng Qi Wenxiang Dong Mengran Guo Panqin Ma Jing Wang; The objective of the present study was to exhibit the enhanced water-solubility and in vivo oral absorption when febuxostat(FXT) became the salt formation of choline. The formation of the choline salt of febuxostat wa...; 关键词：CHOLINE FEBUXOSTAT Characterization PREPARATION In VITRO release BIOAVAILABILITY

FEBUXOSTAT