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Electrocatalytic Hydrogen Evolution by Binuclear Metal (M=Co,Fe,Mn) Xanthine Bridged Bis-corrole: 《Chemical Research in Chinese Universities》2024年第6期1106-1115,共10页XU Shiyin CEN Jinghe YANG Gang SI Liping XIAO Xinyan LIU Haiyang; supported by the National Natural Science Foundation of China(Nos.21671068,22005052);the Research Fund Program of Guangdong Provincial Key Laboratory of Fuel Cell Technology,China(No.FC202211).; Three binuclear metal (M=Co,Fe,Mn) xanthine bridged bis-corrole complexes were synthesized and investigated as electrocatalysts for the hydrogen evolution reaction (HER).All the prepared metal bis-corrole catalysts ex...; 关键词：Electrocatalysis Bis-corrole Hydrogen evolution reaction Transition metal

Antioxidant soy peptide can inhibit xanthine oxidase activity and improve LO_(2) cell damage: 《Food Bioscience》2023年第2期814-824,共11页Yifei Dong Na Sun Qi Ge Renzhi Lv Songyi Lin; This work was supported by the National Key Research and Development Program of China(2017YFD0400504).; In this study,SHECN(Ser-His-Glu-Cys-Asn)and SHCMN(Ser-His-Cys-Met-Asn)soybean peptides were used as the research objects to investigate their antioxidant activities and XO(xanthine oxidase)activity reduction effects.T...; 关键词：Soy protein peptides HYPERURICEMIA ANTIOXIDANT Xanthine oxidase Fluorescence quenching Molecular docking

Paper-based fluorescent devices for multifunctional assays:Biomarkers detection,inhibitors screening and chiral recognition: 《Chinese Chemical Letters》2022年第9期4405-4410,共6页Wang Li Xiaoyue Zhang Siqi Chen Yibing Ji Ruijun Li; financially supported by the National Natural Science Foundation of China (No. 21804141);“Double First-Class University” Project (Nos. CPU2018GY07 and CPU2018GY21); The development of a single analytical platform with different functions is highly desirable but remains a challenge at present.Here,a paper-based device based on fluorescent carbon dots(CDs)functionalized paper/MnO_(...; 关键词：Paper-based devices MULTIFUNCTIONAL XANTHINE Inhibitor screening Chiral recognition

Adenosine A1 receptor ligands bind toα-synuclein:implications forα-synuclein misfolding andα-synucleinopathy in Parkinson’s disease: 《Translational Neurodegeneration》2022年第1期809-834,共26页Elisabet Jakova Mohamed Taha Moutaoufik Jeremy S.Lee Mohan Babu Francisco S.Cayabyab; the Animal Review and Ethics Board(AREB)of the University of Saskatchewan(Animal Use Protocol#20070090).; Background:Accumulatingα-synuclein(α-syn)aggregates in neurons and glial cells are the staples of many synucleinopathy disorders,such as Parkinson’s disease(PD).Since brain adenosine becomes greatly elevated in age...; 关键词：Alpha-synucleinopathy Adenosine A1 receptor N6-cyclopentyladenosine 8-cyclopentyl-1 3-dipropylxanthine 1-aminoindan 2-aminoindan Neuroprotection Neurodegeneration Protein misfolding

Oxidase Enzyme Activities and Their Correlations with Antioxidative Stress Biomarkers in Patients with Acute Coronary Syndrome in Bangladesh: 《World Journal of Cardiovascular Diseases》2020年第4期163-177,共15页Nourin Ferdausi Md. Eahsanul Karim Anik Nabila Nawar Binti Laila N. Islam; Acute coronary syndrome (ACS) is a range of conditions associated with decreased blood flow in the coronary arteries resulting from sudden rupture of atherosclerotic plaques. Several studies have found that oxidative ...; 关键词：ACS XANTHINE OXIDASE NADPH OXIDASE CERULOPLASMIN GLUTATHIONE REDUCTASE

Effects of febuxostat on atrial remodeling in a rabbit model of atrial fibrillation induced by rapid atrial pacing被引量：2: 《Journal of Geriatric Cardiology》2019年第7期540-551,共12页Yong-Yan FAN Feng XU Chao ZHU Wen-Kun CHENG Jian LI Zhao-Liang SHAN Yang LI Yu-Tang WANG; supported by the Beijing Natural Science Foundation(Z141100002114050); Background Febuxostat,a novel nonpurine selective inhibitor of xanthine oxidase(XO),may be used in the prevention and management of atrial fibrillation(AF).The purpose of this study was to evaluate the effects of febu...; 关键词：ATRIAL FIBRILLATION ATRIAL remodeling FEBUXOSTAT Rapid ATRIAL PACING XANTHINE OXIDASE

<i>In Silico</i>and <i>in Vitro</i>Approach for the Understanding of the Xanthine Oxidase Inhibitory Activity of Uruguayan Tannat Grape Pomace and Propolis Poliphenols: 《Journal of Biophysical Chemistry》2019年第1期1-14,共14页Elena Alvareda Federico Iribarne Victoria Espinosa Pablo Miranda Daniela Santi Sara Aguilera S. Bustos Margot Paulino Zunini; The use of food additives with xanthine oxidase (XO) inhibitory activity offers an alternative approach to hyperuricemic and gout disease treatment, and provides an example of antioxidant nutraceutics. The in vitro an...; 关键词：PROPOLIS Tannat Grape POMACE XANTHINE OXIDASE Inhibition Polyphenols Functional Foods

High uric acid model in Caenorhabditis elegans被引量：1: 《Food Science and Human Wellness》2019年第1期63-66,共4页Zhenjing Li Yibin Xue Nifei Wang Jingli Cheng Xiaoying Dong Qingbin Guo Changlu Wang; a grant from the Scientific Research Fund of Tianjin University of Science and Technology(No.20120105);National Natural Science Foundation of China(No.31701551).; To establish experimental high uric acid model in C.elegans.Hypoxanthine,adenine,xanthine,and uric acid were used to treat C.elegans and then hyperuricemic C.elegans was evaluated by allopurinol.Hyperuricemic C.elegan...; 关键词：HYPERURICEMIA C.elegans Uric acid XANTHINE Xanthine oxidase

Effect of TongFengNing Decoction on Uric Acid Levels and Xanthine Oxidase Activity in Hyperuricemia Rats: 《TMR Modern Herbal Medicine》2018年第4期189-197,共9页Jian-hui Wang Jie-mei Guo Bao-lin Li Fang-zhou Teng Ya-ju Zhu Jian-ping Lin Yan Xiao Xiao Mao Lu-lu Huang You-xin Su; Objective To observe the effect of TongFengNing Decoction （TD） on uric acid levels, xanthine oxidase （XOD） activity, and XOD mRNA expression of hyperuricemia （HUA） model rats. Methods： 90 rats were randomly ...; 关键词：TongFengNing HYPERURICEMIA Xanthine oxidase Uric acid Traditional Chinese medicine

Relationship between Mean Arterial Pressure, Uric Acid and Calcium with Xanthine Oxidase Activity and Fetal Outcome in Normotensive and Preeclampsia in a Nested Study: 《Open Journal of Obstetrics and Gynecology》2018年第14期1532-1548,共17页Ranjeeta Gadde Dayanand Chikkanayakanahalli Doddaiah Sheela Shimoga Rangappa; Preeclampsia is a pregnancy complication;early identification with increased risk is one of the key goals in obstetrics. In a nested case control study, serum uric acid and calcium measured in first and second trimest...; 关键词：Uric Acid Mean ARTERIAL Pressure PREECLAMPSIA Nested CASE-CONTROL FETAL Outcome

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