NEPHROTOXICITY

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Hydrogen Sulfide Alleviates Lipid Peroxidation-Mediated Carbonyl Stress in Uranium-Intoxicated Kidney Cells via Nrf2/ARE Signaling
《Biomedical and Environmental Sciences》2025年第4期484-500,共17页Jialin Liu Min Wang Rui Zhang Jifang Zheng Xixiu Jiang Qiaoni Hu 
supported by the National Natural Science Foundation of China(No.82160627);the Natural Science Foundation of the Guangxi Autonomous Region(No.2020GXNFSAA297262)。
Objective To explore the protective effects and underlying mechanisms of H_2S against lipid peroxidation-mediated carbonyl stress in the uranium-treated NRK-52E cells.Methods Cell viability was evaluated using CCK-8 a...
关键词：Hydrogen sulfide(H_2S) Carbonyl stress Lipid peroxidation URANIUM NEPHROTOXICITY NRF2 
Glyphosate Based-Herbicide Induced Nephrotoxicity through Oxidative Stress and the Imbalance of Osmotic Pressure in Mice
《Biomedical and Environmental Sciences》2024年第12期1453-1457,共5页Lei Qi Jinfeng Zhu Yanbo Qi Hong Chao Yu Cheng Xiaolei Yang Hongjie Li Gang Li Jicheng Liu 
supported by the Fundamental Research Funds for the Department of Education in Heilongjiang Province(Grant No.2020-KYYWF-0037 and No.2019-KYYWF-1277);National Natural Science Foundation of China(No.82103869);Project of Qiqihar Academy of Medical Sciences(Grant No.QMSI2019M-23,No.QMSI2019M-05 and No.2024-ZDPY-003);Technology Plan Joint Guidance Project of Qiqihar(Grant No.LHYD-202007);Doctor Youth Fund of Qiqihar Academy of Medical Sciences(Grant No.QMSI2023B-13);Technology Plan Joint Guidance Project of Qiqihar(Grant No.LSFGG-2024100).
Glyphosate-based herbicides(GBHs)are used for weeding purposes in orchards and rubber plantations,as well as in the cultivation of tea mulberry and genetically modified crops.In recent years,GBH has become the most wi...
关键词：rubber CHELATE RESIDUES 
Bioinformatics Analysis and Identification of Key Candidate Genes Associated with Nephrotoxicity Induced by Cobalt
《Biomedical and Environmental Sciences》2023年第2期201-205,共5页WANG Rui ZHANG Ding ZHUGE Rui Jian XUE Qian HE Chang Hao MA Wen Xuan SHEN Zhu Bin GUO Li 
funded by the Grant of the Department of Science and Technology of Jilin Province,grant number[20200201156JC];Jilin Province Health Science and Technology ability advancement project,grant number[2022Jc081].
Cobalt(Co)is a silver-gray,high-intensity,widely distributed metal element that exists in cobalt compounds,and its common valences are bivalence(Co2+)and trivalence(Co3+)[1].The main routes of Co-exposure are occupati...
关键词：VALENCE SILVER COBALT 
Efficacy of Gold Nanoparticles against Nephrotoxicity Induced by Schistosoma mansoni Infection in Mice被引量：2
《Biomedical and Environmental Sciences》2016年第11期773-781,共9页Mohamed A Dkhil Mona F Khalil2 Amira A Bauom Marwa SM Dia Saleh A1-Qura 
the Deanship of Scientific Research at King Saud University for funding the study through the research group project No.RG-198
Objective In this study, the ameliorative effects of gold nanoparticles （gold NP） on the renal tissue damage in Schistosoma mansoni （S. mansoni）-infected mice was investigated. Methods High-resolution transmission...
关键词：Gold nanoparticles SCHISTOSOMIASIS Renal damage Gene expression HISTOPATHOLOGY Oxidative stress 
Melamine Nephrotoxicity is Mediated by Hyperuricemia被引量：1
《Biomedical and Environmental Sciences》2015年第12期904-912,共9页ZHANG Long LI Hong Tian WANG Lin Lin TRACHTMAN Howard TRASANDE Leonardo WANG Pei Xin LIU Jian Meng 
supported by National Natural Science Foundation of China(grant number:81072372)
Objective We tested whether melamine nephrotoxicity was exacerbated by urate(a typical component of renal stones in humans)in rats with hyperuricemiainduced by the uricase inhibitor,potassium oxonate(Oxo).Methods Rats...
关键词：MELAMINE NEPHROTOXICITY HYPERURICEMIA UROLITHIASIS 
Toxicity Evaluation of Freshwater Cyanobacterium Microcystis aeruginosa PCC 7806: Ⅱ Nephrotoxicity in Rats被引量：7
《Biomedical and Environmental Sciences》1997年第1期93-101,共9页R. BHATTACHARYA K. SUGENDRAN R. S. DANGI AND P. V. LAKSHMANA RAO (Division of Pharmacology and Toxicology, Division of Synthetic Chem istry, Defence Research and Development Establishment, Jhansi Road, Gwalior 002, India) (Address correspondence t 
Nephrotoxic potential of laboratory cultures of freshwater cyanobacterium (blue-green al ga) Microcystis aeruginosa PCC 7806 (Pasteur Institute) was assessed in male rats. The ani mals were injected intraperitoneall...
关键词：PCC Nephrotoxicity in Rats Toxicity Evaluation of Freshwater Cyanobacterium Microcystis aeruginosa PCC 7806 
Inability of Nitrendipine to Protect against Gentamicin Nephrotoxicity in the Rat
《Biomedical and Environmental Sciences》1989年第2期160-166,共7页S.KACEW 
Daily sc injection of gentamicin(100 mg/kg)for 4 days produced a significant decrease in the activities of renal cortical Na^+,K^+-ATPase and alkaline phosphatase.The observed reduction in renal functional enzymatic m...
关键词：alkaline PHOSPHOLIPID PHOSPHOLIPASE ATPASE concurrent administration dissolved inability alone lowering 
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