RACEMATE

作品数:14被引量:9H指数:2
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相关领域:理学更多>>
相关作者:牟男孙洪良王丽韫刘克良郑建全更多>>
相关机构:军事医学科学院更多>>
相关期刊:《International Journal of Organic Chemistry》《Journal of Chinese Pharmaceutical Sciences》《Journal of Innovative Optical Health Sciences》《Transactions of Tianjin University》更多>>
相关基金:国家自然科学基金更多>>
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A useful quantitative model for determination of enantiomeric composition of racemate praziquantel by ultraviolet spectroscopy combined with partial least squares and its application to praziquantel tablets
《Journal of Innovative Optical Health Sciences》2018年第3期46-53,共8页Man Zhao Ran Meng Yifang Lu Lingyun Hu Na Sun Lei Nie Haina Wang 
supported by National Natural Science Foundation of China(No.81102504);Key Technologies R&D Program of Shandong Province(No.2016GSF201003);the Scienti¯c Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry(the 50th Batch).
A simple and novel method has been proposed to determine the enantiomeric composition ofracemate praziquantel(PzQ)by using the analysis of ultraviolet(UV)spectroscopy combinedwith partial least squares(PLS),This metho...
关键词:Enantiomeric compositions PRAZIQUANTEL partia last squares utraviolet spectrscopy SUCROSE 
Effect of Crystallization Conditions on Polymorphic Diversity of Malic Acid RS-Racemate
《Transactions of Tianjin University》2013年第2期86-91,共6页Isakov A I Kotelnikova E N Kryuchkova L Yu Lorenz H 
Supported by the Russian Fund for Basic Research (RFBR) under Grant No. 10-05-00891 and 12-05-00876
Enantiomers (R (+) and S(-)), RS-racemate mixture of enantiomers) of malic acid C4H605 have been (double compound) and (R + S) -conglomerate (mechanical investigated by means of X-ray diffractometry and ...
关键词:POLYMORPHISM RACEMIC CHIRAL 
Preparation of Optically Active Alkoxy-serines from Amino-amide Racemate Catalyzed by Escherichia coli Cells with Peptidase B Activity
《Chemical Research in Chinese Universities》2013年第1期95-98,共4页WANG Zhi-yuan LIU Jun-zhong XU Li-sheng ZHANG Hong-juan LIU Qian JIAO Qing-cai 
Alkoxy-L-serines are useful for peptide syntheses. The demand for alkoxy-L-serines in the pharmaceutical industries continues to increase because of their multiple physiological effects. In this research, an improved ...
关键词:Alkoxy-serine DL-β-Alkoxy-a-amino propionamide Enzymatic resolution Peptidase B 
Suggested New Terms for Describing Chiral States and the State-Dependent Behavior of Chiral Systems
《International Journal of Organic Chemistry》2012年第3期224-232,共9页Karel D. Klika 
Deficiencies in the terminology used to describe chiral systems exist for behaviors under various processes and thus a more general, robust terminology is considered. For example, the descriptions for characterizing m...
关键词:STEREOCHEMISTRY Terminology CHIRALITY State-Dependent BEHAVIOR CONGLOMERATE RACEMATE 
Proposed Extension to the Natta Projection Notation System for Enabling an Indication of Relative Stereochemistry and the Stereochemical State被引量:1
《International Journal of Organic Chemistry》2011年第4期215-217,共3页Karel D. Klika 
A system of structure depiction, as an extension of the wedge and hashed wedge bonds (Natta projection), and text notation is herein suggested that embodies more explicit information—or reduced over-statement as circ...
关键词:STEREOCHEMISTRY Stereochemical DESCRIPTORS Natta PROJECTION RACEMATE ENANTIOMER 
Resolution of Alcohol Racemate by Oil
《Green and Sustainable Chemistry》2011年第1期7-11,共5页Adi Wolfson Nadia Komyagina Christina Dlugy Janine Blumenfeld 
Vegetable oil was successfully used as solvent and acyl donor in the kinetic resolution of several secondary alcohol racemates yielding high enantioselectivities. Using vegetable oil as solvent and acyl donor allowed ...
关键词:OIL KINETIC RESOLUTION LIPASE Separation 
Characterization of subtype selection properties of R-(-)-DM-phencynonate hydrochloride and its racemate on muscarinic receptors
《Journal of Chinese Pharmaceutical Sciences》2009年第2期121-127,共7页王丽韫 孙洪良 牟男 仲伯华 刘克良 郑建全 
National Natural Science Foundation of China (Grant No. 30672445)
In order to compare the potential selectivity of R-(-)-DM-phencynonate hydrochloride with its racemate (±)-DM- phencynonate hydrochloride on acetylcholine muscarinic receptor subtypes, the five human acetylcholin...
关键词:Optical isomers Muscarinic acetylcholine receptors (mAChRs) Subtype receptor selectivity Radioligand binding assay 
Is the required therapeutic effect always achieved by racemic switch of proton-pump inhibitors?被引量:4
《World Journal of Gastroenterology》2008年第16期2617-2619,共3页Quan Zhou Xiao-Feng Yan Wen-Sheng Pan Su Zeng 
Supported by Zhejiang Provincial Bureau of Education, No. 20070227;Zhejiang Medical Association, No.2007ZYC18;Association of Zhejiang Hospital Administration, No. 2007AZHA-KEB312
Many of the drugs currently used in medical practice are racemates. The enantiomers of a racemic drug differ in pharmacodynamics and/or pharmacokinetics, thus in some cases it is preferable to develop pure enantiomers...
关键词:Proton-pump inhibitors ENANTIOMER RACEMATE STEREOISOMERISM Racemic switch Pharmacokinetics PHARMACODYNAMICS Cytochrome P450 Genotype 
Preparation of (S)-mandelic acid from racemate using growing cells of Pseudomonas putida ECU1009 with (R)-mandelate degradation activity
《中国生物学文摘》2007年第3期10-10,共1页Huang, H. R. Xu, J. H. 
关键词:(S)-扁桃酸 恶臭假单胞菌 生物降解 外消旋酸盐 (R)-扁桃酸盐 降解活性 
High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa
《中国生物学文摘》2007年第2期5-5,共1页Nie, Y. Xu, Y. Mu, X. Q. Tang, Y. Jiang, J. Sun, Z. H. 
关键词:(R)-2-辛醇 外消旋物 假丝酵母 玫瑰 
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