TIGHT-JUNCTION

作品数:4被引量:13H指数:1
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相关期刊:《World Journal of Gastroenterology》《Journal of Intensive Medicine》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金更多>>
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Beyond wrecking a wall:revisiting the concept of blood–brain barrier breakdown in ischemic stroke被引量:1
《Neural Regeneration Research》2025年第7期1944-1956,共13页Julia Castillo-González Elena González-Rey 
supported by the grants from the Spanish Ministry of Economy and Competitiveness(SAF2017-85602-R);the Spanish Ministry of Science and Innovation(PID2020-119638RB-I00 to EGR);FPU-program(FPU17/02616 to JCG)。
The blood–brain barrier constitutes a dynamic and interactive boundary separating the central nervous system and the peripheral circulation.It tightly modulates the ion transport and nutrient influx,while restricting...
关键词:blood–brain barrier disruption drug delivery ischemic stroke NEUROINFLAMMATION tight-junctions 
Carbon monoxide-releasing molecule-2 protects intestinal mucosal barrier function by reducing epithelial tight-junction damage in rats undergoing cardiopulmonary resuscitation
《Journal of Intensive Medicine》2022年第2期118-126,共9页Qingsheng Niu Fang Liu Jun Zhang Xiaojun Yang Xiaohong Wang 
supported by the National Natural Science Foundation of China(Grant No:81460288,81960348).
Background:Ischemia-reperfusion injury(IRI)to the small intestine is associated with the development of systemic inflammation and multiple organ failure after cardiopulmonary resuscitation(CPR).It has been reported th...
关键词:Carbon monoxide-releasing molecule-2 Cardiopulmonary resuscitation Intestinal mucosal barrier Tight junction Inflammation 
Are claudin-5 tight-junction proteins in the blood-brain barrier porous?
《Neural Regeneration Research》2020年第10期1838-1839,共2页David Fisher Shireen Mentor 
The capillaries of the brain are particularly special,as they are not simply conduits for blood,but are primarily responsible to ensure that the neurons function in a strictly regulated homeostatic interstitium.Brain ...
关键词:POROUS POTASSIUM SOLUTE 
Exogenous sphingomyelinase causes impaired intestinal epithelial barrier function被引量:12
《World Journal of Gastroenterology》2007年第39期5217-5225,共9页Jürgen Bock Gerhard Liebisch Joachim Schweimer Gerd Schmitz Gerhard Rogler 
grants from the University of Regensburg, as part of the ReForM-program, and from the German Research Foundation DFG (BO 2529/2-1) to JB
AIM: To test the hypothesis that hydrolysis of sphingomyelin to ceramide changes the composition of tight junctions (TJs) with increasing permeability of the intestinal epithelium. METHODS: Monolayers of Caco-2 cells ...
关键词:CERAMIDE CHOLESTEROL TIGHT-JUNCTION Caco-2 cells Permeability Inflammatory bowel disease 
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