supported by the National Natural Science Foundation of China,Nos.82271257(to YZ)and 82071228(to YZ);Qing Lan Project(to YZ);Open Competition Grant of Xuzhou Medical University(to YZ);Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.KYCX21_2705(to TS)。
Microglia-mediated neuroinflammation is considered a pathological feature of Parkinson's disease.Triggering receptor expressed on myeloid cell-1(TREM-1)can amplify the inherent immune response,and crucially,regulate i...
supported by the grants from the Projects of Heping Hospital Affiliated to Changzhi Medical College(Nos.HPYJ201921,HPYJ202218,HPYJ202210);the Scientific and Technological Innovation Programs(STIP)of Higher Education Institutions in Shanxi(No.2021L351);the Research Fund of Changzhi Medical College(No.BS202115);the Department of Science and Technology of Shanxi(No.202203021211107);the Health Commission of Shanxi Province(No.2022021).
Diabetes accelerates vascular senescence,which is the basis for atherosclerosis and stiffness.The activation of the NOD-like receptor family pyrin domain containing 3(NLRP3)inflammasome and oxidative stress are closel...