POLYGLUTAMINE

作品数:13被引量:11H指数:2
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相关领域:生物学医药卫生更多>>
相关作者:胡红雨林芳秦正红何晓辉贾娜丽更多>>
相关机构:中国科学院上海生命科学研究院苏州大学中国科学技术大学华南理工大学更多>>
相关期刊:《Open Journal of Genetics》《Science China(Life Sciences)》《中国组织化学与细胞化学杂志》《Neuroscience Bulletin》更多>>
相关基金:国家自然科学基金国家教育部博士点基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Profiling neuroprotective potential of trehalose in animal models of neurodegenerative diseases:a systematic review
《Neural Regeneration Research》2023年第6期1179-1185,共7页Kah Hui Yap Shahrul Azmin Suzana Makpol Hanafi Ahmad Damanhuri Muzaimi Mustapha Jemaima Che Hamzah Norlinah Mohamed Ibrahim 
supported by Dana Impak Perdana Grant(DIP-2019-007)received by NMI from Universiti Kebangsaan Malaysia.
Trehalose,a unique nonreducing crystalline disaccharide,is a potential disease-modifying treatment for neurodegenerative diseases associated with protein misfolding and aggregation due to aging,intrinsic mutations,or ...
关键词:amyotrophic lateral sclerosis autophagy neurodegenerative disease NEUROINFLAMMATION polyglutamine tract protein refolding spinocerebellar ataxia SYNUCLEINOPATHY tau pathology TREHALOSE 
Cell-based therapeutic strategies for treatment of spinocerebellar ataxias:an update被引量:2
《Neural Regeneration Research》2023年第6期1203-1212,共10页Joana Sofia Correia Sara Duarte-Silva António JoséSalgado Patrícia Maciel 
funded by national funds;through the Foundation for Science and Technology (FCT)-project UIDB/50026/2020 and UIDP/50026/2020;by the National Ataxia Foundation (NAF)
Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-adenine-guanine expansion,which encodes a long glutamine tract(polyglutamine)in the respective wild-type protein causing misfolding...
关键词:cell transplantation ENGRAFTMENT induced pluripotent stem cells mesenchymal stem cells neural progenitor cells NEUROPROTECTION polyglutamine spinocerebellar ataxias SECRETOME spinocerebellar ataxia stem cell therapy 
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