This study was supported by Beijing Municipal Science and Technology Project(No.Z171100002217070);National Key R&D Program of China(No.2017YFA0103000);National Science and Technology Key Project on“Major Infectious Diseases such as HIV/AIDS,Viral Hepatitis Prevention and Treatment”(Nos.2012ZX10002004-006,2017ZX10203201-005,2017ZX10201201,2017ZX10202203-006-001 and 2017ZX 10302201-004-002);“Beijing Municipal Administration of Hospitals”Ascent Plan(No.DFL20151601);Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support(Nos.ZYLX201806 and ZYLX202125);Digestive Medical Coordinated Development Center of Beijing Municipal Administration of Hospitals(No.XXZ0503);You An Fund for Liver Diseases and AIDS(No.YNKTTS201801189);Beijing Municipal Natural Science Foun-dation(No.7202068).
Background and Aims:Bilirubin encephalopathy/kernicterus is very rare in adults.This study is aimed to investigate the clinical manifestations and genetic features of two patients with UGT1A1-related kernicterus.Metho...
Background Acute bilirubin encephalopathy (ABE) still represents a significant cause of morbidity and mortality throughout the world,especially in developing countries.We aimed to determine the prevalence of ABE based...
Crigler Najjar syndrome is associated with indirect hyperbilirubinemia due to a deficiency of enzyme Uridine Di Phospho Glucoronosyl Transferase(UDPGT).Presented here is a case of a female in the first trimester of pr...
Several clinical guidelines for the management of infants with severe neonatal hyperbilirubinemia recommend immediate exchange transfusion(ET) when the risk or presence of acute bilirubin encephalopathy is established...
Background:Neonatal hyperbilirubinemia is frequently associated with disproportionately high rates of bilirubin-induced mortality and long-term morbidities in low-and middle-income countries(LMICs).This scoping review...
Phototherapy of a jaundiced neonate is usually started when bilirubin exceeds a threshold in the standard. There are several standards used in the developed countries even though the guideline of American Academy of P...