CYTOTOXIN

作品数：24被引量：103H指数：6
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相关领域：医药卫生更多>>
相关作者：许云禄王晴川刘广芬章良刘厚钰更多>>
相关机构：福建医科大学镇江医学院中国药科大学上海医科大学附属中山医院更多>>
相关期刊：《中国临床神经科学》《Asian Pacific Journal of Tropical Biomedicine》《Cellular & Molecular Immunology》《Science China Chemistry》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>
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Amino acid deletions at positions 893 and 894 of cytotoxinassociated gene A protein affect Helicobacter pylori gastric epithelial cell interactions被引量：1
《World Journal of Gastroenterology》2024年第41期4449-4460,共12页Zhi-Jing Xue Ya-Nan Gong Li-Hua He Lu Sun Yuan-Hai You Dong-Jie Fan Mao-Jun Zhang Xiao-Mei Yan Jian-Zhong Zhang 
Supported by the Shandong Medical and Health Science and Technology Development Plan Project,No.202202080452.
BACKGROUND Helicobacter pylori(H.pylori)persistently colonizes the human gastric mucosa in more than 50%of the global population,leading to various gastroduodenal diseases ranging from chronic gastritis to gastric car...
关键词：Cytotoxin-associated gene A Glu-Pro-Ile-Tyr-Ala Hummingbird phenotype INTERLEUKIN-8 Helicobacter pylori 
Immune response modulation in inflammatory bowel diseases by Helicobacter pylori infection被引量：4
《World Journal of Gastroenterology》2023年第30期4604-4615,共12页Gabriella Feilstrecker Balani Mariana dos Santos Cortez Jayme Euclydes Picasky da Silveira Freitas Fabrício Freire de Melo Ana Carla Zarpelon-Schutz Kádima Nayara Teixeira 
Many studies point to an association between Helicobacter pylori(H.pylori)infection and inflammatory bowel diseases(IBD).Although controversial,this association indicates that the presence of the bacterium somehow aff...
关键词：Cytotoxin-associated antigen A oncoprotein Gut microbiota Helicobacter pylori Helicobacter pylori neutrophilactivating protein Immunological modulation Inflammatory bowel disease NLR family pyrin domain containing 3 inflammasome 
Impact of Helicobacter pylori virulence markers on clinical outcomes in adult populations
《World Journal of Gastroenterology》2023年第1期190-199,共10页Halim Roshrosh Hanan Rohana Maya Azrad Tamar Leshem Segula Masaphy Avi Peretz 
The study was reviewed and approved by the Helsinki Committee of the Baruch Padeh Medical Center,Poriya(Approval No.POR 0007-20).
BACKGROUND In recent years,associations between specific virulence markers of Helicobacter pylori(H.pylori)and gastrointestinal disorders have been suggested.AIM To investigate the presence of virulence factors includ...
关键词：Helicobacter pylori Virulence factors Vacuolating cytotoxin A Cytotoxin-associated gene A Urease activity 
Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions被引量：6
《World Journal of Gastrointestinal Oncology》2021年第7期693-705,共13页Zhang-Ming Chen Jie Hu Yuan-Min Xu Wei He Lei Meng Ting Huang Song-Cheng Ying Zhe Jiang A-Man Xu 
National Natural Science Foundation of China,No.81572350。
BACKGROUND Approximately 90%of new cases of noncardiac gastric cancer(GC)are related to Helicobacter pylori(H.pylori),and cytotoxin-associated gene A(CagA)is one of the main pathogenic factors.Recent studies have show...
关键词：Cytotoxin associated gene A SHP2 CRYPTOTANSHINONE Helicobacter pylori Chronic infection model 
Helicobacter pylori and gastric cardia cancer:What do we know about their relationship?被引量：2
《World Journal of Meta-Analysis》2020年第2期89-97,共9页Jing-Jing Yin Fu-Jiao Duan Sailaja Vatsalya Madhurapantula Yue-Hua Zhang Gui He Kun-Yan Wang Xuan-Ke Ji Kai-Juan Wang 
The incidence of gastric cardia cancer is increasing around the world.Since the discovery of Helicobacter pylori(H.pylori),numerous studies have proved that it is a causative factor for many kinds of digestive system ...
关键词：Gastric CARDIA cancer HELICOBACTER PYLORI Cytotoxin-associated gene A RELATIONSHIP Risk factors Meta-analysis 
Role of Helicobacter pylori virulence factor cytotoxin-associated gene A in gastric mucosa-associated lymphoid tissue lymphoma被引量：9
《World Journal of Gastroenterology》2013年第45期8219-8226,共8页Hong-Ping Wang Yong-Liang Zhu Wei Shao 
Supported by Foundation of Scientific Technology Bureau of Zhejiang Province,No.2010C33118
Helicobacter pylori(H.pylori)infection might initiate and contribute to the progression of lymphoma from gastric mucosa-associated lymphoid tissue(MALT).Increasing evidence shows that eradication of H.pylori with anti...
关键词：HELICOBACTER pylori Cytotoxin-associated GENE A Gastric mucosa-associated LYMPHOID tissue lymphoma LYMPHOMAGENESIS Molecular mechanism 
Biological and chemical diversity of cytotoxin-producing symbiotic marine fungi in intertidal zone of Dalian被引量：4
《Chinese Science Bulletin》2013年第19期2290-2297,共8页ZHANG Yi MU Jun FENG Yan LI HeNan DONG XueWei 
supported by the National Natural Science Foundation of China (20902009);China Postdoctoral Science Foundation (2011M500051);the Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences (kf201009);the Scientific and Technological Fund of Dalian (2008J23JH041)
In this study, the biological and chemical diversity of 8 symbiotic marine fungal strains, with strong cytotoxicity against brine shrimp larvae, were investigated by nucleotide sequencing, morphology and cluster analy...
关键词：生物化学 海洋真菌 多样性 共生 潮间带 RDNA序列分析 聚类分析 大连 
Analysis of the 3' Variable Region of Cytotoxin-Associated Gene A (<i>cagA</i>) in <i>Helicobacter pylori</i>Isolates in China
《Pharmacology & Pharmacy》2013年第5期13-18,共6页Boqing Li Donglong Du Wanju Sun Qizhi Cao Zhen Zhang Zhenzhen Du 
Infection by the bacterium Helicobacter pylori is a putative cause of various gastric disorders, including gastric adenocarcinoma. Incident rates are associated with variants of the H. pylori virulence factor cytotoxi...
关键词：HELICOBACTER pylori CAGA 3' Variable Region China GASTRITIS Gastric Cancer 
Therapeutic potential of snake venom in cancer therapy:current perspectives被引量：5
《Asian Pacific Journal of Tropical Biomedicine》2013年第2期156-162,共7页Vivek Kumar Vyas Keyur Brahmbhatt Hardik Bhatt Utsav Parmar 
Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and cancer.Snake venom toxins coutributed significantly to the treatment of many med...
关键词：SNAKE VENOM CYTOTOXIN ANTICANCER agents Apoptosis INDUCER 
Virulence properties of a peptide hemolysin produced by Enterococcus faecalis
《Advances in Bioscience and Biotechnology》2012年第7期909-917,共9页M.T.Furumura P.M.S.Figueiredo G.V.Carbonell A.L.Darini Maria Rosa Quaresma Bomfim Rosimary de Jesus Gomes Turri Francyelle Costa Moraes Cristina de Andrade Monteiro Herminio Benitez Rabello Mendes Valerio Monteiro Neto T.Yano 
Financial support was provided by Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior(CAPES)and Conselho Nacional de Desenvolvimento Científico e Tecnologico(CNPq),Brazil.
The characterization and prevalence of virulence factors associated with enterococcal invasiveness and severity of disease are important areas to be investigated. Recently, we described the production of a heat-stable...
关键词：Enterococcus Faecalis CYTOTOXIN Heat-Stable Hemolysin Human Epithelial Cells Apoptosis 
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