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作品数:118被引量:435H指数:11
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相关领域:医药卫生生物学更多>>
相关作者:卢桥生郭亚兵侯金林骆抗先姜荣龙更多>>
相关机构:中国人民解放军第一军医大学七台河市种子管理处黑龙江八一农垦大学中国医科大学附属第一医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Mild photothermal therapy-enhanced nano-ferroptosis inducer for potent treatment of advanced prostate cancer
《Nano Research》2025年第4期375-387,共13页Xiao Hu Fei Li Xin-Hang Qian Yu-Sen Zhang Shuai Ke Yun-Xia Jin Shuai Yuan Yuan-Yuan Zhang Rui Li Lei Cao Lang Rao Xian-Tao Zeng Ling-Ling Zhang 
supported by the National Natural Science Foundation of China(Nos.12204358 and 62204214);the Young Top-notch Talent Cultivation Program of Hubei Province(X.-T.Z.);the Fundamental Research Funds for the Central Universities(No.2042023kf0091);the Youth Interdisciplinary Special Fund of Zhongnan Hospital of Wuhan University(No.ZNQNJC2022005).
Androgen deprivation therapy(ADT)and androgen receptor signaling inhibitors(ARSis)often have limited efficacy in patients with advanced prostate cancer(PCa)(especially AR-negative).Inducing ferroptosis in PCa cells is...
关键词:prostate cancer ferroptosis mild photothermal therapy chemodynamic therapy mesoporous polydopamine 
Growth Dilatory Effects of PEG and Sucrose on Geranium wallichianum:An In Vitro Approach for Conservation
《Phyton-International Journal of Experimental Botany》2025年第3期987-1006,共20页Zubair Ashraf Yasar Sajjad Sabaz Ali Khan Gulzar Akhtar Ahmed Mahmoud Ismail Tarek A.Shalaby Bader Alsubaie Othman Al-Dossary 
supported by the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia,grant number KFU242733.
The medicinal herb Geranium wallichianum belongs to the family Geraniaceae. The East Asian Himalayas are its primary habitat. Overexploitation and overharvesting pose a threat to this plant, given its extensive ethnom...
关键词:Indigenously threatened plant G.wallichianum osmotic stress inducer in vitro conservation 
Ferroptosis Inducer RSL3 Inhibits Cell Death by Camptothecin-Induced Apoptosis
《Journal of Biophysical Chemistry》2025年第1期1-13,共13页Koichi Sakurai Aira Koguma Nanako Akita Takeru Miyamoto Aya Fukura Sanae Muraoka Hirayama 
Ferroptosis, an iron-dependent type of cell death, is being considered for new clinical treatments of malignant tumors that are difficult to treat with apoptosis inducers. Although several reports have attempted to in...
关键词:Apoptosis Cell Viability DNA Laddering Ferroptosis Iron PEROXIDE 
Author correction to“The novel ER stress inducer Sec C triggers apoptosis by sulfating ER cysteine residues and degrading YAP via ER stress in pancreatic cancer cells”[Acta Pharm Sin B 12(2022)210-227]
《Acta Pharmaceutica Sinica B》2025年第2期1208-1209,共2页Junxia Wang Minghua Chen Mengyan Wang Wenxia Zhao Conghui Zhang Xiujun Liu Meilian Cai Yuhan Qiu Tianshu Zhang Huimin Zhou Wuli Zhao Shuyi Si Rongguang Shao 
The authors regret that there was an error in the use of GAPDH image in PANC-1 cells of Fig.5B due to mistakenly pasting in the process of assembling figures.The wrong data are replaced by right ones of the same batch...
关键词:mistakenly pasting assembling figuresthe er stress yap APOPTOSIS wrong data gapdh image pancreatic cancer 
Synthesis of Three-Dimensional Chiral Covalent Organic Frameworks Using Surfactant as Inducer in Water
《Chinese Journal of Chemistry》2024年第23期3093-3098,共6页Meiying Huang Zhipeng Zhou Xin Dong Yuyao Li Yonghang Yang Changye Zhan Jiaxing Lu Xiaoshu Wei Yuexian Hong Weiqi Cheng Wei Liu Zhongke Yuan Xudong Chen Zhikun Zheng 
supported by the National Natural Science Foundation of China(52061135103,51873236,52203287);Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.23yxqntd002).
Chiral covalent organic frameworks(COFs)have shown promising applications in asymmetric catalysis,enantiomer separation and chiral recognition due to their tunable structures and permanent porosity.Currently,synthesis...
关键词:Covalent organic frameworks CHIRALITY SURFACTANTS Amino acid derivatives Aqueous-phase synthesis Noncovalent interactions 
Total Synthesis and Stereochemical Assignment of Talaroconvolutin A and Talarofuranone: Gram-scale Synthesis of Ferroptosis Inducer Talaroconvolutin A
《Chinese Journal of Chemistry》2024年第13期1509-1514,共6页Ming Yao Wei Yang Jing Li Chengyun Huang Jin Fang Sulu Qin Shuzhi Liu Xiaolong Yang 
This work was supported by the National Natural Science Foundation of China(Nos.82073714 and 32271539);the National Key Research and Development Program of China(No.2023YFF1104001);Fundamental Research Funds for the Central Universities,South-Central Minzu University(No.CZY23025).
The first total synthesis of talaroconvolutin A(1.1 g obtained)and talarofuranone has been achieved using accessible materials(12 steps,7.5%and 8.2%yields,respectively).Convergent routes involved intramolecular Diels-...
关键词:Natural products ALDEHYDES Total synthesis Domino reactions Biological activity Antitumor agents Ferroptosis Diels-Alder reaction Talaroconvolutin A 
Mitochondria-targeted nano-AIEgens as a powerful inducer for evoking immunogenic cell death
《Chinese Chemical Letters》2024年第5期338-343,共6页Kun-Heng Li Hong-Yang Zhao Dan-Dan Wang Ming-Hui Qi Zi-Jian Xu Jia-Mi Li Zhi-Li Zhang Shi-Wen Huang 
supported by the National Natural Science Foundation of China(Nos.52173137 and 51873163).
AIEgens can serve as an effective platform for the construction of photosensitizer-based immunogenic cell death(ICD)inducers.To date,several mitochondria or endoplasmic reticulum(ER)-targeted aggregationinduced emissi...
关键词:Aggregation induced emission Photodynamic therapy Immunogenic cell death Reactive oxygen species Nanophotosensitizer MITOCHONDRIA 
Current and Potential Roles of Ferroptosis in Bladder Cancer
《Current Medical Science》2024年第1期51-63,共13页Wen-xin AN Radheshyam Gupta Kun ZHAI Ya-ru WANG Wan-hai XU Yan CUI 
supported by the Postdoctoral Scientific Research Developmental Fund of Heilongjiang(No.LBH-Q21130);the Beijing Medical Award Foundation(No.YXJL-2020-1207-0811).
Ferroptosis,a type of regulated cell death driven by iron-dependent lipid peroxidation,is mainly initiated by extramitochondrial lipid peroxidation due to the accumulation of iron-dependent reactive oxygen species.Fer...
关键词:ferroptosis bladder cancer ferroptosis-associated tumor signaling pathway ferroptosis inducer 
Cellular metabolism: A key player in cancer ferroptosis被引量:2
《Cancer Communications》2024年第2期185-204,共20页Xianjie Jiang Qiu Peng Mingjing Peng Linda Oyang Honghan Wang Qiang Liu Xuemeng Xu Nayiyuan Wu Shiming Tan Wenjuan Yang Yaqian Han Jinguan Lin Longzheng Xia Yanyan Tang Xia Luo Jie Dai Yujuan Zhou Qianjin Liao 
This work was sup-ported in part by grants from the following sources:the National Natural Science Foundation of China(82203233,82202966,82173142,82302987,82303534,and 81972636);the Natural Science Foundation of Hunan Province(2023JJ60469,2023JJ40413,2023JJ30372,2023JJ30375,2022JJ80078,and 2020JJ5336);the Research Project of Health Commission of Hunan Province(202203034978,202109031837,and 20201020);Key Research and Devel-opment Program of Hunan Province(2022SK2051);Hunan Provincial Science and Technology Department(2020TP1018);the Changsha Science and Technology Board(kh2201054);the Changsha Municipal Natural Science Foundation(kq2014209);Ascend Foundation of National Cancer Center(NCC201909B06);Hunan Cancer Hospital Climb Plan(ZX2020001-3 and YF2020002);the Science and Technology Innovation Program of Hunan Province(2023RC3199,2023SK4034 and 2023RC1073);by China Postdoctoral Science Foundation(2022TQ0104 and 2022M721118).
Cellular metabolism is the fundamental process by which cells maintain growth and self-renewal.It produces energy,furnishes raw materials,and intermedi-ates for biomolecule synthesis,and modulates enzyme activity to s...
关键词:cancer therapy cellular metabolism ferroptosis inducer ferroptosis 
Plant immune inducer ZNC promotes rutin accumulation and enhances resistance to Botrytis cinerea in tomato
《Stress Biology》2023年第1期387-402,共16页Haipeng Zhao Xiangyu Ding Xiaomeng Chu Haimiao Zhang Xinyu Wang Xinwen Zhang Haoqi Liu Xiaoying Zhang Ziyi Yin Yang Li Xinhua Ding 
supported by the National Key Research and Development Program(2022YFD1402100,2022YFD1401500);major Basic Research Project of Natural Science Foundation of Shandong Province(ZR2022ZD23);the National Natural Science Foundation(32072500,32272557);Shandong Modern Agricultural Industry Technology System(SDAIT-04-08);Shandong Province Key Research and Development Plan(2022TZXD0025,2021TZXD007-04-4);Taishan Scholar Program of Shandong Province.
Gray mold is a destructive disease caused by Botrytis cinerea,a pervasive plant pathogen,which poses a threat to both tomato growth and postharvest storage.The utilization of induced resistance presents a potential st...
关键词:Endophytic fungus extract METABOLOME FLAVONOIDS Tomato gray mold JA Signaling ROS 
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