PSEUDOVIRUS

作品数：14被引量：57H指数：5
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Author correction to"Neutralization of SARSCoV-2 pseudovirus using ACE2-engineered extracellular vesicles"[Acta Pharmaceutica Sinica B 12(2022)1523-1533]
《Acta Pharmaceutica Sinica B》2023年第11期4664-4666,共3页Canhao Wu Qin Xua Huiyuan Wang Bin Tu Jiaxin Zeng Pengtei Zhao Mingjie Shi Hong Qiu Yongzhuo Huang 
The authors regret in the initially published version of this article,there is a misapplied image in Fig.3C.The corrected Fig.3 is provided below.
关键词：CORRECTION initially ACE2 
Evaluation of factors contributing to variability of qualitative and quantitative proficiency testing for SARS-CoV-2 nucleic acid detection被引量：2
《Biosafety and Health》2022年第5期321-329,共9页Yongzhuo Zhang Xia Wang Chunyan Niu Di Wang Qingfei Shen Yunhua Gao Haiwei Zhou Yujing Zhang Yan Zhang Lianhua Dong 
NIM(National Institute of Metrology,China)(AKYZZ2126/AKYYJ2009).
The pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has led to unprecedented social and economic disruption.Many nucleic acid testing(NAT)laboratories in China have been established to co...
关键词：Proficiency testing SARS-CoV-2 Nucleic acid testing Reference material Quality assessment PSEUDOVIRUS 
Screening and identification of HTNV_(pv)entry inhibitors with high-throughput pseudovirus-based chemiluminescence被引量：1
《Virologica Sinica》2022年第4期531-537,共7页Xiaojing Wen Li Zhang Qiang Liu Xinyue Xiao Weijin Huang Youchun Wang 
National Science and Technology Major Projects of Infectious Disease(grant number 2018ZX10731101)。
Hantaviruses,such as Hantaan virus(HTNV)and Seoul virus,are the causative agents of Hantavirus cardiopulmonary syndrome(HCPS)and hemorrhagic fever with renal syndrome(HFRS),and are important zoonotic pathogens.China h...
关键词：Hantaan virus(HTNV) High-throughput screening(HTS) INHIBITOR Drug repurposing 
Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity被引量：2
《Nano Research》2022年第5期4181-4190,共10页Ming Xia Md Rejaul Hoq Pengwei Huang Wen Jiang Xi Jiang Ming Tan 
The research described in this study was supported by the National Institute of Allergy and Infectious Diseases(NIAID,No.R56 AI148426-01A1 to M.T.);Cincinnati Children Hospital Medical Center(CCHMC,Innovation Funds 2018-2020,GAP Fund 2020-2021,and Research Innovation and Pilot Grant 2020-2021 to M.T.);the Center for Clinical and Translational Science and Training(CCTST)of the University of Cincinnati College of Medicine(Pilot Collaborative Studies Grant 2018-2019 to M.T.);that was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health(No.UL1TR001425).
Even with implementation of current influenza vaccines,influenza still claims up to 500,000 lives worldwide annually,indicating a need for a better vaccine strategy.We have developed a technology to generate unique S_...
关键词：S_(60)nanoparticle pseudovirus nanoparticle influenza virus influenza vaccine HEMAGGLUTININ NOROVIRUS 
Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles被引量：2
《Acta Pharmaceutica Sinica B》2022年第3期1523-1533,F0004,共12页Canhao Wu Qin Xu Huiyuan Wang Bin Tu Jiaxin Zeng Pengfei Zhao Mingjie Shi Hong Qiu Yongzhuo Huang 
support of National Special Project for Significant Drugs Development(2018ZX09711002-010-002,China);National Natural Science Foundation of China(81925035 and 81521005,China);Shanghai Sci-Tech Innovation Initiative(19431903100,18430740800,China);the Shanghai Collaborative Innovation Group of Early Diagnosis and Precise Treatment of Hemangiomas and Vascular Malformations(SSMUZDCX20180701,China);the Sanofi-SIBS Yong Faculty Award,and The Youth Innovation Promotion Association;。
The spread of coronavirus disease 2019(COVID-19)throughout the world has resulted in stressful healthcare burdens and global health crises.Developing an effective measure to protect people from infection is an urgent ...
关键词：SARS-CoV-2 COVID-19 Spike protein PSEUDOVIRUS Extracellular vesicles ACE2 Intranasal administration NEUTRALIZATION 
Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles被引量：2
《Biosafety and Health》2022年第1期38-44,共7页Sheng Wang Lizhen Liu Can Wang Ziqiang Wang Xuhua Duan Gang Chen Hu Zhou Hong Shao 
This work was supported by grants 2020‐SKT‐14 and 2021‐YKT‐01 from the Shanghai Institute for Food and Drug Control;LX‐2021‐06 from the Shanghai Drug Administration;19DZ2294600 from the Shanghai Science and Technology Committee.
The coronavirus disease 2019(COVID‐19)is still causing a wide range of infections and deaths due to the high variability of the severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2).Therefore,it is necessary ...
关键词：COVID‐19 SARS‐CoV‐2 variants PSEUDOVIRUS Neutralizing antibody RBD 
Recent Developments in SARS-CoV-2 Neutralizing Antibody Detection Methods被引量：6
《Current Medical Science》2021年第6期1052-1064,共13页Jo-Lewis BANGA NDZOUBOUKOU Yan-di ZHANG Xiong-lin FAN 
supported by grants from the Applied Basic Research Key Project of Wuhan Municipal Bureau of Science and Technology(2020020601012218);the Fundamental Research Funds for the Central Universities(HUST COVID-19 Rapid Response Call No.2020kfyXGYJ040).
The ongoing Coronavirus disease 19 pandemic has likely changed the world in ways not seen in the past.Neutralizing antibody(NAb)assays play an important role in the management of the severe acute respiratory syndrome ...
关键词：Coronavirus disease 19 severe acute respiratory syndrome coronavirus-2 neutralizing antibodies viral neutralization test plaque reduction neutralization test pseudovirus-based neutralization assays enzyme-linked immunosorbent assay lateral flow immunoassays 
Monitoring Neutralization Property Change of Evolving Hantaan and Seoul Viruses with a Novel Pseudovirus-Based Assay被引量：9
《Virologica Sinica》2021年第1期104-112,共9页Tingting Ning Ling Wang Shuo Liu Jian Ma Jianhui Nie Weijin Huang Xuguang Li Yuhua Li Youchun Wang 
supported by the National Science and Technology Major Projects of Drug Discovery[Grant Number 2018ZX09101-001]
The Hantaan virus(HTNV)and Seoul virus(SEOV)mutants have accumulated over time.It is important to determine whether their neutralizing epitopes have evolved,thereby making the current vaccine powerless.However,it is i...
关键词：Hemorrhagic fever with renal syndrome(HFRS) Hantaan virus(HTNV) Seoul virus(SEOV) Pseudovirus-based neutralization assay(PBNA) Amino acid substitution Vaccine 
Development and effectiveness of pseudotyped SARS-CoV-2 system as determined by neutralizing efficiency and entry inhibition test in vitro被引量：6
《Biosafety and Health》2020年第4期226-231,共6页Ren Yang Baoying Huang Ruhan A Wenhui Li Wenling Wang Yao Deng Wenjie Tan 
support this work:The National Key Research and Development Program of China(No.2016YFD0500301,No.2020YFC0842100);the National Major Project for Control and Pre-vention of Infectious Disease in China(No.2018ZX10101002).
With the development of the COVID-19 epidemic,there is an urgent need to establish a system for determining the effectiveness and neutralizing activity of vaccine candidates in biosafety level 2(BSL-2)facilities.Previ...
关键词：Pseudotyped PSEUDOVIRUS SARS-CoV-2 COVID-19 Neutralization assay Viral entry assay 
Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2被引量：17
《Genes & Diseases》2020年第4期551-557,共7页Jie Hu Qingzhu Gao Changlong He Ailong Huang Ni Tang Kai Wang 
This work was supported by the Emergency Project from the Science&Technology Commission of Chongqing(cstc2020jscx-fyzx0053);a Major National Science&Technology Program grant(2017ZX10202203)from the Science&Technology Commission of China,the Leading Talent Program of CQ CSTC(CSTCCXLJRC201719);the Scientific Research Innovation Project for Postgraduate in Chongqing(CYB19168);the Emergency Project for Novel Coronavirus Pneumonia from the Chongqing Medical University(CQMUNCP0302).
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the causative virus of the coronavirus disease 2019(COVID-19)pandemic.To establish a safe and convenient assay system for studying entry inhibitors and neu...
关键词：Antiviral therapeutics CORONAVIRUS Neutralizing antibodies PSEUDOVIRUS SARS-CoV-2 Spike protein 
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