AUTOFLUORESCENCE

作品数:41被引量:104H指数:7
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相关领域:医药卫生更多>>
相关作者:宁向艳李丽更多>>
相关机构:首都医科大学东北师范大学更多>>
相关期刊:《International Journal of Ophthalmology(English edition)》《外科研究与新技术(中英文)》《Medical Bulletin of Shanghai Jiaotong University》《Chemical Research in Chinese Universities》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划俄罗斯基础研究基金中国博士后科学基金更多>>
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Correlating NAD(P)H lifetime shifts to tamoxifen resistance in breast cancer cells:A metabolic screening study with time-resolved flow cytometry
《Journal of Innovative Optical Health Sciences》2025年第1期101-115,共15页Samantha Valentino Karla Ortega-Sandoval Kevin D.Houston Jessica P.Houston 
the National Institute of Health for supporting this research under grants NIH R35GM152076,NIH 1SC1GM127175-01,NIH T32GM148394.
Time-resolved flow cytometry(TRFC)was used to measure metabolic differences in estrogen receptor-positive breast cancer cells.This specialty cytometry technique measures fluorescence lifetimes as a single-cell paramet...
关键词:TIME-RESOLVED flow cytometry AUTOFLUORESCENCE fluorescence lifetime breast cancer metabolism 
Aβ-Aggregation-Generated Blue Autofluorescence Illuminates Senile Plaques as well as Complex Blood and Vascular Pathologies in Alzheimer’s Disease
《Neuroscience Bulletin》2024年第8期1115-1126,共12页Hualin Fu Jilong Li Chunlei Zhang Peng Du Guo Gao Qiqi Ge Xinping Guan Daxiang Cui 
supported by the National Natural Science Foundation of China(81472235);the Shanghai Jiao Tong University Medical and Engineering Project(YG2021QN53,YG2017MS71);the International Cooperation Project of National Natural Science Foundation of China(82020108017);the Innovation Group Project of National Natural Science Foundation of China(81921002).
Senile plaque blue autofluorescence was discovered around 40 years ago,however,its impact on Alzheimer’s disease(AD)pathology has not been fully examined.We analyzed senile plaques with immunohistochemistry and fluor...
关键词:Senile plaque Blue autofluorescence  Amyloid aggregation Hemoglobin Cathepsin D.Microaneurysm Alzheimer's disease 
Comparison between standard and wide-field autofluorescence in detection of retinal displacement after rhegmatogenous retinal detachment surgery
《Advances in Ophthalmology Practice and Research》2022年第3期32-37,共6页Raquel Maroto Cejudo Cristina Blanco Marchite Teresa Prieto Moran Sergio Copete Piqueras 
Purpose To analyse the differences between 30°blue autofluorescence(BAF30),55°blue autofluorescence(BAF55)and 200°green Ultra-Wide Field autofluorescence(UWF200)imaging to detect retinal displacement(RD)after vitre...
关键词:Blue fundus autofluorescence Green fundus autofluorescence Rhegmatogenous retinal detachment Retinal displacement Retinal vessel printings 
Deep learning autofluorescence-harmonic microscopy被引量:7
《Light(Science & Applications)》2022年第4期697-710,共14页Binglin Shen Shaowen Liu Yanping Li Ying Pan Yuan Lu Rui Hu Junle Qu Liwei Liu 
the National Natural Science Foundation of China(61935012/62175163/61961136005/61835009/62127819);Shenzhen Key Projeas(JCYJ20200109105404067);Shenzhen International Cooperation Project(GJHZ20190822095420249)for financial support。
Laser scanning microscopy has inherent tradeoffs between imaging speed,field of view(FOV),and spatial resolution due to the limitations of sophisticated mechanical and optical setups,and deep learning networks have em...
关键词:NETWORKS DEEP HARMONIC 
Rare-earth Doped Nanoparticles with Narrow NIR-II Emission for Optical Imaging with Reduced Autofluorescence被引量:1
《Chemical Research in Chinese Universities》2021年第4期943-950,共8页LU Feng ZHAO Ting SUN Xiaojun WANG Zuqiang FAN Quli HUANG Wei 
This work was supported by the National Natural Science Foundation of China(Nos.21975131,21674048);the Fund of Synergetic Innovation Center for Organic Electronics and Information Displays;the Primary Research&Development Plan of Jiangsu Province,China(No.BE2016770).
Fluorescence imaging in the second near-infrared region(900―1700 nm, NIR-II) with a high resolution and penetration depth due to the significantly reduced tissue scattering and autofluorescence has emerged as a usefu...
关键词:Second near-infrared RARE-EARTH Downconversion nanoparticle AUTOFLUORESCENCE Fluorescence imaging 
Characteristics of normal human retinal pigment epithelium cells with extremes of autofluorescence or intracellular granule count被引量:1
《Annals of Eye Science》2021年第1期11-19,共9页Katharina Bermond Andreas Berlin Ioana-Sandra Tarau Christina Wobbe Rainer Heintzmann Christine A.Curcio Kenneth R.Sloan Thomas Ach 
Dr.Werner Jackstädt Foundation(TA),NIH/NEI 1R01EY027948(TA,RH,CAC),1R01EY06109(CAC).
Background:Cells of the retinal pigment epithelium(RPE)accumulate different kinds of granules(lipofuscin,melanolipofuscin,melanosomes)within their cell bodies,with lipofuscin and melanolipofuscin being autofluorescent...
关键词:Retinal pigment epithelium(RPE) GRANULES autofluorescence(AF) LIPOFUSCIN melanolipofuscin MELANOSOMES 
Hyperspectral autofluorescence characterization of drusen and sub-RPE deposits in age-related macular degeneration
《Annals of Eye Science》2021年第1期20-27,共8页Yuehong Tong Thomas Ach Christine A.Curcio RTheodore Smith 
NIH/NEI R01 EY027948(CC,YT,RTS,TA).
Background:Soft drusen and basal linear deposit(BLinD)are two forms of the same extracellular lipid rich material that together make up an Oil Spill on Bruch’s membrane(BrM).Drusen are focal and can be recognized cli...
关键词:Age-related macular degeneration sub-RPE deposits DRUSEN hyperspectral autofluorescence(AF) 
Facile thermal decomposition synthesis of sub-5 nm nanodots with long-lived luminescence for autofluorescence-free bioimaging被引量:4
《Science China Materials》2020年第9期1808-1817,共10页Xiaobo Lv Na Chen Jie Wang Quan Yuan 
supported by the National Natural Science Foundation of China(21925401 and 21904100)。
Persistent nanophosphors can remain luminescent after the removal of the excitation.Persistent nanophosphors exhibit great advantages in biomedical fields,particularly in autofluorescence-free bioimaging and in-siteex...
关键词:persistent luminescence thermal decomposition nanoparticles BIOIMAGING 
Quenching autofluorescence in the alimentary canal tissues of Bactericera cockerelli(Hemiptera:Triozidae)for immunofluorescence labeling
《Insect Science》2020年第3期475-486,共12页Xiao-Tian Tang Freddy Ibanez Cecilia Tamborindeguy 
This work was supported by Texas A&M University and Texas A&M AgriLife Research(Controlling Exotic and Invasive Insect-Transmitted Pathogens)and Hatch project TEX0-1-9381 Accession Number 1015773;Xiaotian Tang received the Herb Dean'40 Endowed Scholarship from the Department of Entomology at Texas A&M University.
Immunofluorescence has been widely used to localize microbes or specific molecules in insect tissues or cells.However,significant autofluorescence is frequently observed in tissues which can interfere with the fluores...
关键词:ENDOSYMBIONTS gut IMMUNOFLUORESCENCE Liberibacter pathogen PSYLLID vector 
Resolution and contrast enhancement of laser-scanning multiphoton microscopy using thulium-doped upconversion nanoparticles被引量:1
《Nano Research》2019年第12期2933-2940,共8页Alexey B.Kostyuk Artem D.Vorotnov Andrey V.Ivanov Arthur B.Volovetskiy Aleksandr V.Kruglov Lyudmila M.Sencha Liuen Liang Evgenii L.Guryev Vladimir A.Vodeneev Sergey M.Deyev Yiqing Lu Andrei V.Zvyagin 
High-contrast optical imagi ng is achievable using phosphoresce nt labels to suppress the short-lived background due to the optical backscatterand autofluoresce nee.However,the long-lived phosphorescence is generally ...
关键词:UPCONVERSION NANOPARTICLES AUTOFLUORESCENCE time-gated imaging scanning microscopy time-correlated single photon counting 
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