supported by a grant from the National Natural Science Foundation of China to X.Zhang(32070693)。
In animal cells,the Golgi apparatus serves as the central hub of the endomembrane secretory pathway.It is responsible for the processing,modification,and sorting of proteins and lipids.The unique stacking and ribbon-l...
Apolipoprotein A-IMilano(ApoA-IM)has been shown to significantly reduce coronary atherosclerotic plaques.However,the preparation of cost-effective pharmaceutical formulations of ApoA-IM is limited by the high cost and...
Objective: To analyze the dynamic evaluation of chemiluminescence, colloidal gold, and immunofluorescence chromatography in detecting antibodies in COVID-19 patients within four weeks of infection, and to provide evid...
supported by the National Natural Science Foundation of China(Nos.21975098 and 22275071);the program for JLU Science and Technology Innovative Research Team(No.2017TD-06);the opening funds of State Key Laboratory of Applied Optics,Changchun Institute of Optics,Fine Mechanics and Physics,Chinese Academy of Science,and the China Postdoctoral Science Foundation(Nos.2020TQ0119 and 2020M681046).
Plasmonic enhanced fluorescence(PEF)technology is a powerful strategy to improve the sensitivity of immunofluorescence microarrays(IFMA),however,current approaches to constructing PEF platforms are either expensive/ti...
BACKGROUND Information on liver involvement in patients with coronavirus disease 2019 is currently fragmented.AIM To highlight the pathological changes found during the autopsy of severe acute respiratory syndrome cor...
During the development of mammalian heart, the left and right atria play an important role in cardiovascular circulation. The embryonic atrium is mainly formed by the differentiation of progenitor cells and the prolif...
Background: Worldwide, diabetic nephropathy-DN is the leading cause of end-stage kidney disease-ESKD, DN is a common cause of renal failure with a reported frequency of 10% - 15% in type-2-diabetes-mellitus-T2DM patie...
the National Institutes of Health(NIH);the Intramural Research Program of the NIH,NINDS.
Background: Parkinson’s disease (PD) is characterized by intra-neuronal deposition of the protein α-synuclein (α-syn) and by deficiencies of the catecholamines dopamine and norepinephrine (NE) in the brain and hear...
supported by the National Key R&D Program of China(2019YFA0210103);the National Natural Science Foundation of China(61905122,22174070,21775075,21977053);the Natural Science Foundation of Jiangsu Province(BK20190735);the Research Start-up Fund of Nanjing University of Posts and Telecommunications(NY220149,NY219006);the Fundamental Research Funds for the Central Universities,Nankai University(2122018165)。
Cells are inherently heterogeneous to achieve a diverse spectrum of biological functions.To understand the underlying protein machinery that achieves these fascinating functions,it is important to develop advanced ana...
Objective:To elucidate the epidermal melanocyte distribution according to sex,age,and body part with the goal of providing benchmark data for the diagnosis and therapeutic effect evaluation of pigmentary skin diseases...