GRANULES

作品数：319被引量：696H指数：13
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相关机构：广西中医药大学燕山大学教育部中国食品药品检定研究院更多>>
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Shenfushu granules attenuate diabetic kidney disease by inhibiting PIK3R1/protein kinase B/heparanase-mediated endothelialmesenchymal transition
《World Journal of Diabetes》2025年第5期297-316,共20页Xi-Ding Yang Si-Jia Ma Da-Xiong Xiang Yong-Yu Yang 
Supported by the Changsha Science and Technology Major Project,No.kh2205035;the Hunan Traditional Chinese Medicine Science and Technology Project,No.2021061;the Natural Science Foundation of Hunan Province,No.2025JJ80080。
BACKGROUND Injury to the glomerular filtration barrier causes diabetic kidney disease(DKD),and glomerular endothelial-mesenchymal transition damages the filtration barrier of glomerular endothelial cells.Shenfushu gra...
关键词：Diabetic kidney disease Glomerular filtration barrier GLYCOCALYX Shenfushu granules PIK3R1 Heparanase-1 Endothelial-mesenchymal transition 
Efficacy and Safety of Erzhu Jiedu Decoction Granules in Treating Mid-advanced Hepatitis B Virus-Associated Primary Liver Cancer Patients with Pi(Spleen)-Deficiency and Dampness-Heat Syndrome
《Chinese Journal of Integrative Medicine》2025年第5期394-401,共8页CHENG Yang WANG Hao-yi WAN Cheng-yi SHI Jie-wen JIN Yuan-yuan HE Sheng-li YIN Bao-bing CHEN Jian-jie 
Supported by Shanghai Municipal Science and Technology Commission Foundation(No.21Y11922800);National Natural Science Foundation of China(No.82374189)。
Objective:To assess the efficacy and safety of Erzhu Jiedu Decoction(EZJDD)Granules in treating mid-advanced hepatitis B virus-associated primary liver cancer(HBV-PLC)patients with Pi(Spleen)-deficiency and dampness-h...
关键词：Erzhu Jiedu Decoction Granules hepatitis B virus-associated primary liver cancer Pi(Spleen)-deficiency and dampness-heat syndrome 
TMT-based quantitative proteomics reveals the potential mechanism of the FufangMuji Granules in carbon tetrachloride-induced liver injury
《Traditional Medicine Research》2025年第4期21-30,共10页Lei Men Ya-Qi Shi Xin-Yue Wang Ke-Ke Li Zhong-Yu Li Chun-Bin Li Xiao-Jie Gong 
National Natural Science Foundation of China(82104532 and 82173913);Joint Program(Applied Basic Research Project)of Liaoning Provincial Science and Technology Program(2023JH2/101700074);High-level Talent Innovation Support Program of Dalian(2021RD10);Fundamental Research Funds for the Central Universities(2023-SWGC-0101)。
Background:Fufang Muji Granules is a traditional Chinese medicine of the Manchu ethnic group and is thought to treat hepatitis and liver injury by inhibiting the elevation of alpha-fetoprotein.Methods:In this investig...
关键词：PROTEOMICS Fufang Muji Granules liver injury traditional Chinese medicine 
Qishen Granules Modulate Metabolism Flexibility Against Myocardial Infarction via HIF-1α-Dependent Mechanisms in Rats
《Chinese Journal of Integrative Medicine》2025年第3期215-227,共13页SUN Xiao-qian LI Xuan LI Yan-qin LU Xiang-yu LIU Xiang-ning CUI Ling-wen WANG Gang ZHANG Man LI Chun WANG Wei 
Supported by the National Natural Science Foundation of China(No.82174215);the National Science Fund for Excellent Young Scholars(No.82222075);the National Major Scientific and Technological Special Project for"Significant New Drugs Development"(No.2019ZX09201004-001-011)。
Objective:To assess the cardioprotective effect and impact of Qishen Granules(QSG)on different ischemic areas of the myocardium in heart failure(HF)rats by evaluating its metabolic pattern,substrate utilization,and me...
关键词：Qishen Granules substrate utilization hypoxia-inducible factor-1αpathway energy metabolism heart failure 
Efficacy and safety of Lutai Danshen Baishao granules for treating female melasma:A randomized,double-blind,placebo-controlled trial
《Journal of Traditional Chinese Medical Sciences》2025年第1期71-78,共8页Meiyu Lyu Yi Yang Jinlian Liu Wenting Fei Min Fu Yunting Hong Hongguo Rong Chun Wang Linyuan Wang Jianjun Zhang 
funded by the National Key Research and Development Plan of the Traditional Chinese Medicine Modernization Research Key Project(2018YFC1706800).
Objective:To investigate the potential efficacy and safety of Lutai Danshen Baishao granules(LDBG)for treating female melasma associated with kidney deficiency and blood stasis patterns.Methods:A randomized,double-bli...
关键词：Female melasma Lutai danshen baishao granules Clinical trial Efficacy Safety Traditional Chinese medicine Kidney deficiency Blood stasis 
Review on the research progress into the traditional Chinese medicinal Jing Fang granules:chemical composition,pharmacological effects and clinical applications
《Integrative Medicine Discovery》2025年第6期1-13,共13页Rui Zhao Tai-Li Zhao Hong-Hua Li Pei-Pei Zhao Meng-Meng Wang Yi-Wei Meng Jing-Li Ren Xin Yin Jing-Chun Yao 
supported by the Key R&D Program of Shandong Province,China(No.2024TZXD067,2022SFGC0105);Natural Science Foundation of Shandong Province(No.ZR2023QB021);Young Taishan Scholarship to Xuekui Xia(No.tsqn202103100);Jinan Talent Project for Universities(No.2021GXRC062,202228088);Key innovation Project and Science,Education and Industry Integration Innovation Pilot Project of Qilu University of Technology(Shandong Academy of Sciences)(No.2022JBZ01-06,2024ZDZX03,2023RCKY214).
Jing Fang granules(JFG)are a modern Chinese medicinal formulation derived from Jing Fang Defeating Toxin San(JFDS).JFG primarily contains bioactive compounds such as flavonoids/flavonoid glycosides,coumarins and other...
关键词：chemical composition clinical application Jing Fang granules pharmacological effect traditional Chinese herbal formula 
Effectiveness of combining Qingyanyin formulated granules(轻燕饮配方颗粒) with press needles in treating abdominal obesity:a multicenter randomized controlled trial
《Journal of Traditional Chinese Medicine》2025年第1期107-114,共8页YE Wujie YANG Yawei ZHANG Da TANG Ling CUI Minying FU Bin ZHANG Meng HU Xingang ZHAO Yan 
National Key Research and Development Project:Clinical Evaluation of the Interventional Techniques for Abdominal Obesity(No.2019YFC1710102)。
OBJECTIVE:To assess the efficacy and safety of the Qingyanyin formulated granules(轻燕饮配方颗粒,QYY),press needles(PN),and their combined application in addressing abdominal obesity(AO).This trial aims to offer a mor...
关键词：obesity abdominal body mass index press needle randomized controlled trial Qingyanyin formulated granules 
Study on the Quality Standard of Fuzheng Wangan Granules
《Medicinal Plant》2025年第1期27-29,34,共4页Jiabao MA Yanmei LAN Yin LIU Tingting MO Minggang WANG 
Supported by the Project for the Development and Promotion of Appropriate Technology of Traditional Chinese Medicine in Guangxi(GZSY2024017).
[Objectives]This study aims to establish the quality standard of Fuzheng Wangan granules.[Methods]The qualitative identification of Radix Bupleuri and Radix Paeoniae Alba was carried out by the thin layer chromatograp...
关键词：Fuzheng Wangan granules Quality standard 
Advantages and Application Prospects of Traditional Chinese Medicine Granules
《Proceedings of Anticancer Research》2025年第1期8-13,共6页Xiaohua Sun 
With the advancement of the modernization of traditional Chinese medicine(TCM),TCM granules have emerged and garnered widespread attention.This study provides a comprehensive review of the development of TCM granules,...
关键词：TCM granules Advantages Clinical application Preventive healthcare 
Xiangshao Granules Ameliorate Post-stroke Depression by Inhibiting Activation of Microglia and IDO1 Expression in Hippocampus and Prefrontal Cortex
《Chinese Journal of Integrative Medicine》2025年第1期28-38,共11页LI Cheng-gang XU Lu-shan SUN Liang XU Yu-hao CAO Xiang ZHAO Chen-chen XIA Sheng-nan ZHANG Qing-xiu XU Yun 
Supported by the National Natural Science Foundation of China(No.82130036,81920108017);Jiangsu Province Key Medical Discipline(No.ZDXKA2016020);the Key Research and Development Program of Jiangsu Province of China(No.BE2020620)。
Objective To investigate the therapeutic effect of Xiangshao Granules(XSG)on post-stroke depression(PSD)and explore the underlying mechanisms.Methods Forty-three C57BL/6J mice were divided into 3 groups:sham(n=15),PSD...
关键词：post-stroke depression Xiangshao Granules indoleamine 2 3-dioxygenase 1 Chinese medicine 
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