Background: Sugar moiety of macromolecules is today very well known for its implications in many biological recognition mechanisms including cell-cell, extracellular matrix-cell and/or bacteria-cell interactions. In t...
This work was supported in part by an ANRS grant(No.D15236)to F.P.B;This work was also supported by the Cardiff University President's Research Scholarship to M.A.C.;grants from lSSF-WT and the Gates Foundation to V.P;G.M.was the recipient of a postdoctoral fellowship from Labex EpiGenMed(Montpelier,France)and is currently supported by the ANRS.
Interferons(IFNs)are“warning signal”cytokines released upon pathogen sensing.IFNs control the expression of interferonstimulated genes(ISGs),which are often crucial to restrict viral infections and establish a cellu...
We would like to thank the personnel of the Bergman clinic in Bilthoven, the Netherlands for providing healthy donor skin. We would like to thank Tom O'Toole for the technical assistance with imaging flow cytometry. The present work was funded by KWF (VU2009-2598), the Dutch Science Foundation (NWO, VENI Grant NO 863.10.017), the European Research Council (ERCAdvanced339977), and NanoNext 3D01.
The potential of the skin immune system to generate immune responses is well established, and the skin is actively exploited as a vaccination site. Human skin contains several antigen-presenting cell subsets with spec...
Supported by grants from the Estonian Research Foundation,No.7749 and No.8334;EU Regional Developmental Fund;the Estonian Ministry of Education and Research,No.SF 0180035s08 and No.IUT20-43
AIM: To investigate the densities of dendritic cells(DCs) and FOXP3+ regulatory T cells(Tregs) and their interrelations in the small bowel mucosa in untreated celiac disease(CD) patients with and without type 1 diabet...