LECTIN

作品数：183被引量：308H指数：9
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相关机构：中国科学院四川大学中国科学院力学研究所武汉大学更多>>
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Natural variations of maize ZmLecRK1 determine its interaction with ZmBAK1 and resistance patterns to multiple pathogens被引量：3
《Molecular Plant》2024年第10期1606-1623,共18页Zhenju Li Junbin Chen Chuang Liu Shengfeng He Mingyu Wang Lei Wang Vijai Bhadauria Shiwei Wang Wenyu Cheng Hui Liu Xiaohong Yang Mingliang Xu You-Liang Peng Wangsheng Zhu 
supported by Biological Breeding-National Science and Technology Major Project(no.2023ZD04070,W.Z.);the National Key Research and Development Program,Ministry of Science and Technology of China(no.2022YFD1201802,W.Z.);the National Natural Science Foundation of China(no.32472499,W.Z.);the Pinduoduo-China Agricultural University Research Fund(no.PC2023A01005,Y.-L.P.).
Maize(Zea mays)is one of the most important crops in the world,but its yield and quality are seriously affected by diverse diseases.Identifying broad-spectrum resistance genes is crucial for developing effective strat...
关键词：natural variation G-type lectin receptor-like kinase co-receptor BAK1 broad-spectrum resistance genome-wide association study MAIZE 
Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2
《Cellular & Molecular Immunology》2024年第5期495-509,共15页Ronja Wieboldt Michael Sandholzer Emanuele Carlini Chia-wei Lin Anastasiya Börsch Andreas Zingg Didier Lardinois Petra Herzig Leyla Don Alfred Zippelius Heinz Läubli Natalia Rodrigues Mantuano 
supported by funding from the Swiss National Science Foundation(SNSF Grant No.310030-215237/1);the Schoenmakers-Müller Foundation,a research grant from Ono Pharmaceuticals,and the Cancer League of Basel(KlbB).Open access funding provided by University of Basel.
The overexpression of sialic acids on glycans,called hypersialylation,is a common alteration found in cancer cells.Sialylated glycans can enhance immune evasion by interacting with sialic acid-binding immunoglobulin-l...
关键词：sialoglycans Sialic acid-binding immunoglobulin-like lectin tumor microenvironment myeloid derived suppressor cells 
Morphological determination of localization and function of Golgi proteins
《Biophysics Reports》2024年第2期121-132,共12页Yusheng Xing Yannan Jian Xiaodan Zhao Yue Zhang Zhenqian Zhang Xing Zhang Xiaoyan Zhang 
supported by a grant from the National Natural Science Foundation of China to X.Zhang(32070693)。
In animal cells,the Golgi apparatus serves as the central hub of the endomembrane secretory pathway.It is responsible for the processing,modification,and sorting of proteins and lipids.The unique stacking and ribbon-l...
关键词：Golgi apparatus Golgi fragmentation IMMUNOFLUORESCENCE Super-resolution microscopy Electron microscopy Lectin staining GLYCOSYLATION 
Duality of jacalin-related lectin:Master regulator and chaperone
《Plant Communications》2024年第2期4-6,共3页Ganesh Alagarasan 
Lectins have chaperone-like activity with carbohydrate-binding sites,which are key in cellular homeostasis.However,the specific interactions between lectins and endoplasmic reticulum(ER)proteins during stress are uncl...
关键词：critical stress MASTER 
Targeting stroma and tumor,silencing galectin 1 treats orthotopic mouse hepatocellular carcinoma被引量：3
《Acta Pharmaceutica Sinica B》2024年第1期292-303,共12页Tahereh Setayesh Ying Hu Farzam Vaziri Xin Chen Jinping Lai Dongguang Wei Yu-Jui Yvonne Wan 
The authors thank the Genomics Shared Resource(GSR)core facility at the University of California,Davis Health,Dr.Clifford G Tepper,Stephanie Liu,Ryan Davis,for helping in performing spatial RNA sequencing,and William Amato for his assistance in the quantification of immunohistochemistry slides.This manuscript is supported by grants funded by the USA National Institutes of Health(NIH)T32 CA108459e15,R01CA222490,R50CA243787.BioRender was used to draw mice figures in schematic experimental design.
This study examines inhibiting galectin 1(Gal1)as a treatment option for hepatocellular carcinoma(HCC).Gal1 has immunosuppressive and cancer-promoting roles.Our data showed that Gal1 was highly expressed in human and ...
关键词：Liver Hepatocellular carcinoma Carbohydrate-binding lectin Galectin 1 Extracellular matrix Translation Spatial transcriptomics Tumor-margin 
基于高凝集素亲和性载体的抗生素吸入粉雾剂用于高效治疗细菌生物膜相关肺部感染
《Science Bulletin》2023年第24期3225-3239,M0006,共16页周钥 黄嘉元 王冠林 翟紫照 Maizbha Uddin Ahmed 夏晓 刘岑峰 金玉珍 潘昕 黄莹 吴传斌 张雪娟 
supported by the National Natural Science Foundation of China(82104072 and 82373802);the Guangzhou Municipal Science and Technology Project(202201010424)。
多重耐药细菌引发的肺部感染对人类健康构成了严重威胁.细菌生物膜加剧了肺部感染的持续和复发,限制了抗生素的可及性和有效性.基于凝集素竞争策略和颗粒表面修饰策略,本研究设计了一种硫酸多粘菌素B(PMBS)的吸入粉雾剂(DPI)用于治疗肺...
关键词：Pulmonary infections Polymyxin B Dry powder formulation BIOFILM High-lectin-affinity sugar 
The proteome landscape of the root cap reveals a role for the jacalin-associated lectin JAL10 in the salt-induced endoplasmic reticulum stress pathway被引量：1
《Plant Communications》2023年第6期179-196,共18页Krishna Kodappully Das Ankita Mohapatra Abin Panackal George Sreenivas Chavali Katja Witzel Eswarayya Ramireddy 
supported by IISER Tirupati and by an Early Career Research award from the Science and Engineering Research Board,Department of Science and Technology,Govt.of India(ECR/2016/001071)to E.R.K.K.D.acknowledges the CSIR-JRF fellowship and Bi-nationally supervised doctoral degree scholarship from DAAD(91730390)for her PhD.A.M.and A.P.G.acknowledge funding from IISER Tirupati for graduate studies.S.C.acknowledges funding from IISER Tirupati and the Ramalingaswami Re-entry Fellowship(BT/RLF/Re-entry/05/2018)Department of Biotechnology,Government of India.
Rapid climate change has led to enhanced soil salinity,one of the major determinants of land degradation,resulting in low agricultural productivity.This has a strong negative impact on food security and environmental ...
关键词：Arabidopsis root cap cell-type specific proteomics salt stress ER stress jacalin-associated lectin 
Effect of a Thermal Spring Water on Carbohydrate-Protein Interactions in In-Vitro Models Implicating Normal Human Keratinocytes and Recombinant Lectins
《Journal of Cosmetics, Dermatological Sciences and Applications》2023年第4期269-276,共8页Benoît Roubinet Ludovic Landemarre Karim Mekideche Jean-Eric Branka Luc Lefeuvre 
Background: Sugar moiety of macromolecules is today very well known for its implications in many biological recognition mechanisms including cell-cell, extracellular matrix-cell and/or bacteria-cell interactions. In t...
关键词：Carbohydrate-Protein Interaction LECTIN DECTIN-1 LANGERIN Normal Human Keratinocytes Immune System 
A novel lectin from mushroom Phellodon melaleucus displays hemagglutination activity,and antitumor activity in a B16 melanoma mouse model
《Food Science and Human Wellness》2023年第5期1885-1892,共8页Yuanhui Li Peng Wang Zejun Zhang Qinghong Liu 
supported by grants from the China Agriculture Research System(CARS-20-01A)。
A novel lectin(termed PML)was purified from fruiting bodies of the edible mushroom Phellodon melaleucus(division Basidiomycota)by ion exchange,hydrophobic interaction,and gel filtration chromatographies,with overall t...
关键词：Phellodon melaleucus LECTIN Hemagglutination activity Cytokine IL-10 Antitumor activity 
Novel compound heterozygous variants in lectin mannose-binding 2-like gene identified in a Chinese autosomal recessive mental retardation-52(MRT52)patient with phenotype expansion
《Chinese Medical Journal》2023年第17期2107-2109,共3页Cong Zhou Xing Wei Yuanyuan Xiao Shanling Liu Jing Wang 
National Key Research and Development Program of China(No.2021YFC1005300);Program of Science and Technology Department of Sichuan Province(No.2022YFS0244)
To the Editor:Autosomal recessive mental retardation-52(MRT52,OMIM:616887)was first reported in 2016 and is characterized by global developmental delay,[1]severe intellectual disability(ID),speech disorder,and seizure...
关键词：EXPANSION EXACT delay 
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