DENDROBINE

作品数:5被引量:21H指数:2
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相关领域:医药卫生农业科学更多>>
相关作者:李卫东孙静更多>>
相关机构:西南交通大学伊犁师范大学更多>>
相关期刊:《Medicinal Plant》《Acta Pharmacologica Sinica》《有机化学》《Asian Pacific Journal of Tropical Medicine》更多>>
相关基金:国家自然科学基金中央高校基本科研业务费专项资金新疆维吾尔自治区高校科研计划更多>>
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Pharmacological Action and Mechanism of Dendrobine
《Medicinal Plant》2023年第6期88-90,98,共4页Jingjing WEN Wenshuang HOU Anqi WANG Jiazhu LI Jundong GUAN Zhe LIU Changtao CAI Chenghao JIN 
Supported by The Central Talent Training Project for Local University Reform and Development(2020GSP16);Guidance Project of Key R&D Plan in Heilongjiang Province(GZ20220039);Innovative Research Project for Postgraduates of Heilongjiang Bayi Agricultural University(YJSCX2022-Y55).
Dendrobine,an alkaloid extracted from the stem of Dendrobium nobile Lindl.,has many biological activities such as anti-cancer effect,anti-inflammation effect,anti-influenza A virus effect,treatment of leukemia,treatme...
关键词:DENDROBINE ANTI-CANCER ANTI-INFLAMMATION Anti-influenza A virus Leukemia treatment 
Metabolic characterization of a potent natural neuroprotective agent dendrobine in vitro and in rats被引量:2
《Acta Pharmacologica Sinica》2022年第4期1059-1071,共13页Hong Pan Fu-guo Shi Chao Fang Jing-shan Shi 
This study was financially supported by the National Natural Science Foundation of China[U1812403];the Pharmacy National First-class Discipline Construction Project of Guizhou Province of China[GNYL(2017-006)].
Dendrobine is the main sesquiterpene alkaloid of Dendrobium nobile Lindl, which exhibits potent neuroprotective activity. However, its metabolism and disposition are little known. In this study, we investigated the me...
关键词:DENDROBINE neuroprotective agent drug metabolism cytochrome P450 metabolic stability UPLC-Q/Orbitrap MS 
倍半萜生物碱Dendrobine的全合成研究进展被引量:2
《有机化学》2021年第7期2636-2649,共14页肖检 彭羽 李卫东 
国家自然科学基金(No.21772078);中央高校基本科研业务费专项资金(Nos.2682019CX70,2682019CX71,2682020CX55);新疆维吾尔自治区高校科研计划项目(重点项目)(No.XJEDU2018I018)资助项目.
石斛碱(Dendrobine)是一类从传统中药金钗石斛中分离得到的具有Picrotoxane倍半萜碳骨架的生物碱类天然产物.由于该化合物具有多环稠合和七个连续立体中心的结构特点,以及镇痛和退热等药理活性,引起了众多有机合成化学家和药物化学家的...
关键词:天然产物 倍半萜生物碱 石斛碱 全合成 木防己毒烷 
Influence of light intensity and water content of medium on total dendrobine of Dendrobium nobile Lindl被引量:7
《Asian Pacific Journal of Tropical Medicine》2017年第11期1095-1100,共6页Jin-Ling Li Zhi Zhao Hong-Chang Liu Chun-Li Luo Hua-Lei Wang 
supported by Natural Science Foundation of China(No.81603237);Joint Funding Project of Guizhou Province[QKH LH Zi(2015)No.7670];Youth Science and Technology Talent Development Project of Education Department in Guizhou Province[QJH KY Zi(2016)No.119];Natural Science Foundation of Guizhou Province[QKH Basics(2017)No.1403];Talent Base Project of Organization Department in Guizhou Province[QRLF(2013)No.15];Key Discipline Project of Education Department in Guizhou Province[QXWH Zi ZDXK(2014)No.8];Regular Higher Education Institution Project of Key Laboratory of Genetic Improvement and Physiology and Ecology of Grain and Oil Crops of Guizhou Province of China[Grant No.KY(2015)333]
Objective: To ascertain the influence of light intensity and water content of medium on the total dendrobine of Dendrobium nobile(D. nobile).Method: The principal component analysis combined with total dendrobine accu...
关键词:Dendrobium nobile Light intensity Water content of medium Total dendrobine Principal component analysis 
A New Dendrobine-Type Alkaloid from Dendrobium nobile被引量:10
《Chinese Chemical Letters》2003年第3期278-279,共2页Qun Fang LIU Wei Min ZHAO 
A new dendrobine-type alkaloid has been isolated from stems of Dendrobium nobile lindl.. Its structure has been identified on the basis of spectroscopic method.
关键词:Dendrobium nobile ORCHIDACEAE ALKALOID dendronobiline A. 
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