TUMOR-SUPPRESSOR

作品数：7被引量：44H指数：2
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Identification of tumor-suppressor genes in lung squamous cell carcinoma through integrated bioinformatics analyses被引量：1
《Oncology Research》2024年第1期187-197,共11页HENG LI YOUMING LEI GAOFENG LI YUNCHAO HUANG 
Department of Science and Technology of Yunnan Province,Provincial Basic Research Program(Kunkun-Medical Joint Special Project),202101AY070001-134;Yunnan Provincial Department of Science and Technology,Yunnan Provincial Gerontology Research Center,202102AA310069;Yunnan Provincial Department of Science and Technology-Kunming Medical University Basic Research Joint Special Key Project,202201AY070001-136.
Lung cancer is a prevalent malignancy,and fatalities of the disease exceed 400,000 cases worldwide.Lung squamous cell carcinoma(LUSC)has been recognized as the most common pathological form of lung cancer.The comprehe...
关键词：LUSC DEGs WGCNA PPI network TUMOR-SUPPRESSOR 
RNF43 is a novel tumor-suppressor and prognostic indicator in clear cell renal cell carcinoma被引量：2
《Oncology Research》2021年第3期159-174,共16页DAWEI ZHU LEI ZHANG XIAOKAI SHI SHENGLIN GAO CHUANG YUE LIFENG ZHANG YU BAI QIFENG WANG ATSUSHI OKADA TAKAHIRO YASUI CHAO WANG XINGANG CUI LI ZUO 
supported by the Top-Level Clinical Discipline Project of Shanghai Pudong (PWYgf2018-03);National Natural Science Foundation of China (Nos.81773154,81902565,81772747,81974391);Shanghai Natural Science Foundation (No.20ZR1449600);Pudong New Area Science and Technology Development Fund Special Fund for People’s Livelihood Research (Medical and Health) (PKJ2019-Y19);Young Scientists Foundation of Changzhou No.2 People’s Hospital (2019K008);Changzhou Sci&Tech Program (CJ20190100);the Program of Shanghai Academic/Technology Research Leader (No.19XD1405100).
Identifying prognostic indicators of clear cell renal cell carcinoma(ccRCC)and elucidating the mechanisms underlying ccRCC progression are crucial for improving ccRCC patient prognosis.This study investigated the clin...
关键词：Clear cell renal cell carcinoma RNF43 PROGNOSIS YAP Tumor progression 
Tumor-suppressor microRNA-139-5p restrains bladder cancer cell line ECV-304 properties via targeting Connexin 43被引量：1
《Chinese Medical Journal》2019年第19期2354-2361,共8页Qiang Chi Zhi-Yong Wang Hong-Yang Li Dian-Bin Song Hui Xu Guang Ma Ze-Min Wang Xiu-Ming Li 
Background:In our previous paper,we demonstrated that Connexin 43(CX43)was highly expressed in bladder cancer(BC)tissues.But the molecular mechanism about microRNAs(miRNAs)regulation upstream of CX43 in BC has not bee...
关键词：BLADDER cancer CONNEXIN 43 MICRORNAS 
Tumor-suppressor effects of chemical functional groups in an in vitro co-culture system
《Frontiers of Materials Science》2014年第2期136-141,共6页Su-Ju xu Fu-Zhai CUI Xiang-Dong KONG 
Acknowledgements This work was in part supported by the National Basic Research Program of China （Grant No. 2011 CB606205）, the National Natural Science Foundation of China （Grant No. 51272236）, and the Program for 521 Excellent Talents ofZhejiang Sci-Tech University.
Liver normal cells and cancer cells co-cultured on surfaces modified by different chemical functional groups, including mercapto （-SH）, hydroxyl （-OH） and methyl （-CHz） groups. The results showed that different ...
关键词：tumor suppressor chemical functional group co-culture system regen-erative medicine material 
Deciphering tumor-suppressor signaling in flies:Genetic link between Scribble/Dlg/Lgl and the Hippo pathways
《Journal of Genetics and Genomics》2011年第10期461-470,共10页Masato Enomoto Tatsushi Igaki 
Loss of apico-basal polarity is one of the crucial factors that drives epithelial tumor progression, scribbleldiscs largellethal giant larvae （scrib/dlg/lgl）, a group of apico-basal polarity genes, were initially id...
关键词：Cell polarity Hippo pathway DROSOPHILA SCRIBBLE DLG lgl TUMOR-SUPPRESSOR Tumor progression 
A novel tumor-suppressor candidate gene-ndr2 is differentially expressed between osteoarthritis synovium cells and rheumatoid arthritis synovium fibroblasts
《Journal of Medical Colleges of PLA(China)》2004年第6期342-345,共4页邓艳春 王吉村 刘新平 药立波 
Objective: To test whether the novel tumor-suppressor candidate gene-ndr2 is also differentially expressed between osteoarthritis synovium cells (OASC) and rheumatoid arthritis synovium fibroblasts (RASF), and whether...
关键词：ndr2 rheumatoid arthritis synovium flbroblasts differential expression gene 
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation被引量：40
《World Journal of Gastroenterology》2003年第1期54-58,共5页Jing Lan Yong-Yan Xiong Yi-Xian Lin Bi-Cheng Wang Ling-Ling Gong Hui-Sen Xu Guang-Song Guo Department of Pathology,Zhongnan Hospital,Wuhan University,Wuhan city 430071,Hubei Province,China 
the National Science Fund of Hubei Province,No. 98J087;the Department of Health of Hubei Province,No.WJ01572
AIM: To investigate the relationship between Helicobacterpylori (H. pylori) infection and the expressions of the p53,Rb, c-myc, bcl-2 and hTERT mRNA in a series of diseasesfrom chronic gastritis (CG), intestinal metap...
关键词：胃癌 幽门螺杆菌 肿瘤抑制因子 端粒酶 免疫组织化学 
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