The authors thank the funding from the National Key R&D Program of China(Grant No.:2021YFF0600704 and 2021YFF0600701).
Currently,several disulfide-rich peptides have been officially approved as therapeutic medicines,such as w-conotoxin ziconotide[1],guanosine analogue linaclotide,and plecanatide.Peptides are predisposed to generate re...