ANTI-CALCIFICATION

作品数：5被引量：4H指数：1
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A strategy for mechanically integrating robust hydrogeltissue hybrid to promote the anti-calcification and endothelialization of bioprosthetic heart valve被引量：1
《Regenerative Biomaterials》2024年第2期123-136,共14页Haoshuang Wu Nuoya Chen Tiantian Zheng Li Li Mengyue Hu Yumei Qin Gaoyang Guo Li Yang Yunbing Wang 
supported by National Key Research and Development Programs(2022YFB3807303 and 2022YFB3807305),National Natural Science Foundation of China(32101107)and CAMS InnovationFundforMedical Sciences(2021-12M-5-013)。
Bioprosthetic heart valve(BHV)replacement has been the predo-minant treatment for severe heart valve diseases over decades.Most clinically available BHVs are crosslinked by glutaraldehyde(GLUT),while the high toxicity...
关键词：bioprosthetic heart valves recombinant humanized collagen typeⅢ ENDOTHELIALIZATION ANTI-CALCIFICATION ANTI-COAGULATION 
Polyphenol based hybrid nano-aggregates modified collagen fibers of biological valve leaflets to achieve enhanced mechanical,anticoagulation and anti-calcification properties
《Collagen and Leather》2023年第4期116-130,共15页Shufen Li Shiying Lang Zhiqian Chen Jingruo Chen Weihua Zhuang Yangrui Du Yawen Yao Gongyan Liu Mao Chen 
supported by the National Natural Science Foundation of China(81970325 and 82170375);Key Research and Development Support Project of Science&Technology Department of Chengdu(2021-YF08-00121-GX);Post-Doctor Research Project,West China Hospital,Sichuan University(Grant No.20HXBH164 and 20HXBH105);Chinese Medical Association Cardiovascular Branch(CSC)Clinical Research Special Fund Project(CSCF2020B04);West China Hospital"1.3.5"Discipline of Excellence Project-"Percutaneous transcatheter aortic valve implantation";"Mechanisms of aortic stenosis and the clinical applications"(ZYGD20002).
Glutaraldehyde(Glut)-crosslinked porcine pericardium and bovine pericardium are mainly consisted of collagen and widely used for the preparation of heterogenous bioprosthetic heart valves(BHV),which play an important ...
关键词：Tannic acid Bioprosthetic heart valve Antibacterial and anti-calcification 
Functional non-glutaraldehyde treated porcine pericardium for anti-coagulation,anti-calcification,and endothelial proliferation bioprosthetic heart valves
《Journal of Leather Science and Engineering》2022年第1期320-332,共13页Xiaotong Chen Tao Yu Qunshou Kong Dajun Kuang Hong Xu Zhiyu Zhao Li Yang Gaocan Li Haojun Fan Yunbing Wang 
National Key Research and Development Programs(2020YFC1107802);the National Natural Science Foundation of China(32071357);the Sichuan Science and Technology Program(2021YFH0011),Sichuan Province Major Science and Technology Special Projects(2018SZDZX0011),the National 111 project of Introducing Talents of Discipline to Universities(No.B16033).We would be grateful to the help of VENUS Medtech Inc.(Hangzhou,China)for providing the fresh porcine pericardium.
In the last decade,the number of transcatheter heart valve replacement for severe heart valve disease has increased exponentially.Although the bioprosthetic artificial heart valve(BHV)has similar fluid dynamics perfor...
关键词：Bioprosthetic heart valves Oxazolidine CYTOCOMPATIBILITY ANTI-COAGULATION 
Polyphenol based hybrid nano-aggregates modified collagen fibers of biological valve leaflets to achieve enhanced mechanical,anticoagulation and anti-calcification properties
《Journal of Leather Science and Engineering》2022年第1期394-408,共15页Shufen Li Shiying Lang Zhiqian Chen Jingruo Chen Weihua Zhuang Yangrui Du Yawen Yao Gongyan Liu Mao Chen 
the National Natural Science Foundation of China(81970325 and 82170375);Key Research and Develop-ment Support Project of Science&Technology Department of Chengdu(2021-YF08-00121-GX);Post-Doctor Research Project,West China Hospital,Sichuan University(Grant No.20HXBH164 and 20HXBH105);Chinese Medical Association Cardiovascular Branch(CSC)Clinical Research Special Fund Project(CSCF2020B04);West China Hospital“1·3·5”Discipline of Excellence Project-“Percutaneous transcatheter aortic valve implantation”and“Mechanisms of aortic stenosis and the clinical applications”(ZYGD20002).
Glutaraldehyde(Glut)-crosslinked porcine pericardium and bovine pericardium are mainly consisted of collagen and widely used for the preparation of heterogenous bioprosthetic heart valves(BHV),which play an important ...
关键词：Tannic acid Bioprosthetic heart valve Antibacterial and anti-calcification 
Preclinical study of a self-expanding pulmonary valve for the treatment of pulmonary valve disease被引量：3
《Regenerative Biomaterials》2020年第6期609-618,共10页Dajun Kuang Yang Lei Li Yang Yunbing Wang 
supported by the National Key Research and Development Programs(SQ2019YFC110002).
In the past decade,balloon-expandable percutaneous pulmonary valves have been developed and applied in clinical practice.However,all the existing products of pulmonary artery interventional valves in the market have a...
关键词：pulmonary valve self-expanding double bell-shaped ANTI-CALCIFICATION PRECLINICAL 
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