云南高校图书馆联盟文献共享服务平台- ANTILEISHMANIAL

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Molecular Docking Studies on Streptomycin Antileishmanial Activity: 《Open Journal of Physical Chemistry》2024年第2期36-48,共13页Todd A. Young Matthew George Jr. Ayele Gugssa William M. Southerland Yayin Fang Clarence M. Lee; Resistance to pentavalent antimonial drugs and the lack of vaccines make it urgent to find novel therapeutic options to treat Leishmaniasis, a tropical disease caused by the Leishmania protozoan parasite. The study re...; 关键词：LEISHMANIASIS STREPTOMYCIN Amphotericin B Molecular Docking AMINOGLYCOSIDES ANTILEISHMANIAL

Ficus carica hairy roots:In vitro anti-leishmanial activity against Leishmania major promastigotes and amastigotes被引量：1: 《Asian Pacific Journal of Tropical Medicine》2022年第5期220-229,共10页Shahla Amani Shahram Khademvatan Mehdi Mohebodini Morad Jafari Vinod Kumar; Objective:To investigate the biochemical capacity,and in vitro inhibitory effects of hairy roots from two cultivars of Ficus carica L.(Sabz and Siah)on Leishmania major promastigotes and amastigotes.Methods:In the hai...; 关键词：Antileishmanial agents Hairy roots IFN-γ Inducible nitric oxide synthase PARASITE Reactive oxygen species

Effect of Vigna radiata, Tamarix ramosissima and Carthamus lanatus extracts on Leishmania major and Leishmania tropica: An in vitro study: 《Chinese Herbal Medicines》2020年第2期171-177,共7页Alisha Akya Roya Chegene Lorestani Hossein Zhaleh Fatemeh Nemati Zargaran Keyghobad Ghadiri Mosayeb Rostamian; supported by Kermanshah University of Medical Sciences(Funding No:97318)。; Objective:Current therapy strategies of leishmaniasis have some problems such as high cost,toxicity and side effects.Plant extracts can be a source of drugs to control leishmaniasis.In this study,the effect of hydroal...; 关键词：antileishmanial agent cutaneous leishmaniasis Carthamus lanatus L Leishmania major Leishmania tropica Tamarix ramosissima Lcdcb Vigna radiata(Linn.)Wilczek

Tioxolone niosomes exert antileishmanial effects on Leishmania tropica by promoting promastigote apoptosis and immunomodulation: 《Asian Pacific Journal of Tropical Medicine》2019年第8期365-374,共10页Maryam Hakimi Parizi Iraj Sharifi Saeedeh Farajzadeh Abbas Pardakhty Mohammad Hossein Daie Parizi Hamid Sharifi Ali Reza Keyhani Mahshid Mostafavi Mehdi Bamorovat Ahmad Khosravi Daryoush Ghaffari; financially supported by the Iran National Science Foundation under Grant ID 95839151 to Saeedeh Farajzadeh; Objective: To explore the antileishmanial effect of tioxolone and its niosomal form against Leishmania tropica. Methods: Tioxolone niosomes were prepared by the hydration method and were evaluated for morphology, size...; 关键词：NIOSOME Tioxolone LEISHMANIA tropica APOPTOSIS

In vitro antileishmanial effects of Physalis angulata root extract on Leishmania infantum: 《Journal of Integrative Medicine》2018年第6期404-410,共7页Bruno Jose Martins Da Silva Sandro Wilson Gomes Pereira Ana Paula Drummond Rodrigues Jose Luiz Martins Do Nascimento Edilene Oliveira Silva; supported by the Conselho Nacional de Desenvolvimento Cientifico e Tecnologico(CNPq-grant number 424820/2016-1);Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior(CAPES);Edital PAPQ PROPESP-UFPA;the Instituto Nacional de Biologia Estrutural e Bioimagem-INBEB(CNPq-grant number 465395/2014); Objective： In the present study, we evaluated the effects of the aqueous extract of Physalis angulata root （AEPa） on Leishmania infanturn proliferation, morphology, and the driving mechanism in leishmanicidal activ...; 关键词：Leishmanicidal activity Leishmania infantum Reactive oxygen species APOPTOSIS Physalis angulata

Synthesis, Crystal Structure, Cytotoxic, Antileishmanial and Docking Evaluation of 3-(4-Chloro-3-nitrophenyl)-1-phenylprop-2-en-1-one: 《Chinese Journal of Structural Chemistry》2018年第8期1250-1258,共9页HAMID Aziz AAMER Saeed FARUKH Jabeen ULRICH Florke QURAT-Ul-Ain NADHMAN Akhter; Chalcone derivatives are of immense importance owing to their superior pharmacological profile. Minor changes in their structures create high degree of diversity that results in a broader spectrum of biological activi...; 关键词：CHALCONE cytotoxicity antfleishmanial Claisen-Schmidt condensation moleculardocking

Using focused pharmacovigilance for ensuring patient safety against antileishmanial drugs in Bangladesh’s National Kala-azar Elimination Programme: 《Infectious Diseases of Poverty》2018年第1期787-799,共13页Md.Sakhawat Hossain Amresh Kumar A.F.M Akhtar Hossain Md.Mahshin Abhijit Sharma Md.Akter Hossain Varun Sharma Rashidul Haque A.K.M Shamsuzzaman Shomik Maruf Prakash Ghosh Vivek Ahuja Dinesh Mondal; This activity was supported by funds from PATH,USA.The funders had no role in the study’s design,data collection and analysis,decision to publish,or preparation of the paper.; Background:Adverse effects of antileishmanial drugs can affect patients’quality of life and adherence to therapy for visceral leishmaniasis(VL)and post-kala-azar dermal leishmaniasis(PKDL).In Bangladesh,there are 26 ...; 关键词：Visceral leishmaniasis PHARMACOVIGILANCE Antileishmanial drugs Health system BANGLADESH

Kigelia africana Fruit:Constituents,Bioactivity, and Reflection on Composition Disparities: 《World Journal of Traditional Chinese Medicine》2017年第4期1-6,共6页Ahmed Galal Osman Zulfiqar Ali Amar G.Chittiboyina lkhlas A.Khan; Objective: Kigelia africana, a tropical tree, which has long been used in African traditional medicine. The objective of the current study has been identifying the constituents of K. africana and verifying its utiliti...; 关键词：Anticryptoccocal ANTILEISHMANIAL cannabinoid receptors Kigelia africana opioid receptors

Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara被引量：1: 《Asian Pacific Journal of Tropical Biomedicine》2017年第8期702-707,共6页Farah Ramdane Rym Essid Nadia Fares Dahmane El Ouassis Sana Aziz Mahfoud Hadj Mahammed Mohamed Didi Ould Hadj Ferid Limam; To study the phytochemical constituents and in vitro biological activities of hydromethanolic extract and fractions from Algerian Sahara Myrtus nivellei (M. nivellei) collected in Hoggar region and to identify the act...; 关键词：Phenolic compounds FLAVONOIDS Antioxidant activity Antimicrobial activity Antileishmanial activity Myrtus nivellei

Promising antileishmanial effectiveness of doxorubicin and Doxil against Leishmania major:An in vitro assay: 《Asian Pacific Journal of Tropical Medicine》2017年第6期614-618,共5页Azar Shokri Javad Akhtari Masoud Keighobadi Mahdi Fakhar Saeed Hosseini Teshnizi Saeed Emami Sajede Sadjjadian; financially supported by Vice Chancellors for Research and Technology of Mazandaran University of Medical Sciences(project number:1919); Objective: To evaluate the effect of doxorubicin and its pegylated liposomal formulation(Doxil, Caelyx) on in vitro susceptibility of promastigote and amastigote stages of Leishmania major. Methods: Throughout in vitr...; 关键词：Leishmania major DOXORUBICIN DOXIL In vitro

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