SANGUINARINE

作品数：16被引量：67H指数：4
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相关领域：医药卫生更多>>
相关作者：应黎更多>>
相关机构：北京大学上海交通大学更多>>
相关期刊：《Precision Medicine Research》《Current Medical Science》《Molecular Plant》《Journal of Traditional Chinese Medicine》更多>>
相关基金：国家自然科学基金广西壮族自治区自然科学基金更多>>
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Dietary sanguinarine supplementation improves the growth performance and intestinal immunity of broilers
《Animal Nutrition》2024年第4期76-89,共14页Yue Su Guanyu Chang Jingyu Liu Peng Huang Jianguo Zeng 
funded by National Key R&D Program of China(2023YFD1301200);the science and technology innovation Program of Hunan Province(2021RC3091).
Dietary sanguinarine(SAN)can enhance the growth performance of poultry and livestock,but the regulatory mechanism of the SAN monomer on intestinal homeostasis and how it promotes growth performance has not yet been cl...
关键词：SANGUINARINE Intestinal immunity Gut microbiota Growth performance BROILER 
Dietary sanguinarine supplementation recovers the decrease in muscle quality and nutrient composition induced by high-fat diets of grass carp(Ctenopharyngodon idella)
《Animal Nutrition》2024年第2期208-219,共12页Yong Shi Lei Zhong Yuanxiang Liu Shude Xu Jihong Dai Yaozhengtai Zhang Yi Hu 
supported by National Natural Science Foundation of China(No.32172985);Postgraduate Research and Innovation Project of Hunan Province(QL20210161).
The intake of high-fat diets(HFD)has been shown to diminish the muscle quality of aquatic animals.Sanguinarine,as an excellent additive,exhibits the capability to reduce fat deposition and alleviate inflammation.Howev...
关键词：Plant extract Muscle feature Myofiber characteristics Muscular texture Protein metabolism 
Sanguinarine suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma via inhibiting mTOR signaling
《Journal of Traditional Chinese Medicine》2022年第5期687-692,共6页YANG Mengzhe ZHANG Beibei LIANG Zhenqiang CHENG Nannan LüAnqiao YANG Jianyu GUO Xingzhe BAI Xianyu HUANG Yuanjiao JIAO Aijun XU Ning 
Supported by Project for Department of Science and Technology of Guangxi Zhuang Autonomous Region,China,Screening,Product Development and Mechanism Research of Anti-Nasopharyngeal Cancer Chinese Medicine Monomers (AB19110052);Natural Science Foundation of Guangxi,China,Epstein-Barr Virus Infection and UpRegulation Mechanism of Invasion and Migration-Related Proteins S100A8 and S100A9 in Nasopharyngeal Carcinoma Cells (2015GXNSFAA139215);National Natural Science Foundation of China,Quantification,Validation,Functional Analysis and Construction of Regulatory Pathway of i TRAQ Serum Protein Molecular Markers in Nasopharyngeal Carcinoma (81260405)。
OBJECTIVE: To confirm the anti-NPC effect of sanguinarine(SA) through a series of wet experiments.METHODS: NPC cell viability was determined by proliferation experiment. Cell clone formation experiment, cell scratch t...
关键词：nasopharyngeal carcinoma SANGUINARINE TOR serine-threonine kinases apoptosis 
Systematic understanding of the underlying target and mechanism of sanguinarine against nasopharyngeal carcinoma through a networkpharmacology approach
《Precision Medicine Research》2020年第3期104-115,共12页Meng-Zhe Yang Bei-Bei Zhang Zhen-Qiang Liang Ning Xu Nan-Nan Cheng An-Qiao Lv Jian-Yu Yang Xing-Zhe Guo Xian-Yu Bai Ai-Jun Jiao Yuan-Jiao Huang 
This research was funded by the Project for Department of Science and Technology of Guangxi Zhuang Autonomous Region,China,grant number Guike AB19110052;the Natural Science Foundation of Guangxi,China,grant number 2015GXNSFAA139215;the National Natural Science Foundation of China,grant number 81260405.
Background:Nasopharyngeal carcinoma is a malignant tumor,well known as a cancer type characterized by regional specificity,especially in Southern China.The network pharmacology is an emerging discipline developed in r...
关键词：Nasopharyngeal carcinoma SANGUINARINE Network pharmacology Drug target 
Stability of Sanguinarine and Chelerythrine in Macleaya cordata (Willd.) R. Br.被引量：1
《Medicinal Plant》2019年第6期20-23,共4页Chunmei LI Xu CHEN Wenlan LI Bingmei LIU Li WANG Yubin JI 
Supported by Post-doctoral Foundation Project of Heilongjiang Province(LBHZ16094);Special Research Fund Project for Scientific and Technological Innovation Talents in Harbin City(2017RAQXJ115);Doctoral Starting up Project of Harbin University of Commerce(2019DS114).
[Objectives]To explore the stability of sanguinarine and chelerythrine in Macleaya cordata(Willd.)R.Br.[Methods]The solubility and stability of sanguinarine and chelerythrine in seven solvents were measured by HPLC.Be...
关键词：Macleaya cordata(Willd.)R.Br. SANGUINARINE CHELERYTHRINE STABILITY 
Sanguinarine Decreases Cell Stiffness and Traction Force and Inhibits the Reactivity of Airway Smooth Muscle Cells in Culture
《Molecular & Cellular Biomechanics》2019年第2期141-151,共11页Mingzhi Luo Kai Ni Peili Yu Yang Jin Lei Liu Jingjing Li Yan Pan Linhong Deng 
Funding for the work was provided by the Key Program of NSF of China(No.11532003);NSF of China(31670950,21607016);the Natural Science Foundation of the Higher Education Institutions of Jiangsu Province,China(17KJB130002);the Applied Basic Research Project of Changzhou(CJ20179039).
Airway hyperresponsiveness(AHR)is the cardinal character of asthma,which involves the biomechanical properties such as cell stiffness and traction force of airway smooth muscle cells(ASMCs).Therefore,these biomechanic...
关键词：Airway smooth muscle cells SANGUINARINE BIOMECHANICS cell stiffness cell traction force 
Simultaneous Quantitative Determination of Nitidine, Chelerythrine and Sanguinarine Using HPTLC from Callus Extract of <i>Zanthoxylum rhetsa</i>
《American Journal of Analytical Chemistry》2018年第8期386-396,共11页Kavitha Perala Veeresham Ciddi 
Nitidine, Chelerythrine and Sanguinarine, all these three alkaloids are benzophenanthridine alkaloids. Nitidine was used as an anti-HIV, anti-malarial and anti-cancer. Chelerythrine had anti-cancer and anti-inflammato...
关键词：Nitidine CHELERYTHRINE SANGUINARINE HPTLC 
Sanguinarine Attenuates Lipopolysaccharide-induced Inflammation and Apoptosis by Inhibiting the TLR4/NF-KB Pathway in H9c2 Cardiomyocytes被引量：22
《Current Medical Science》2018年第2期204-211,共8页Yan-yan MENG Yuan LIU Zhe-fu HU Yao ZHANG Jian NI Zhen-guo MA Hai-han LIAO Qing-qing WU Qi-zhu TANG 
The inflammatory response is involved in the pathogenesis of the most common types of heart disease. Sanguinarine （SAN） has various pharmacological properties such as anti-inflammatory, antioxidant, antibacterial, a...
关键词：LIPOPOLYSACCHARIDES SANGUINARINE INFLAMMATION H9c2 cardiac cells APOPTOSIS 
The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism被引量：24
《Molecular Plant》2017年第7期975-989,共15页Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng 
This work was supported by National Natural Science Foundation of China （31200615, 31600238）, Postgraduate Research and Innovation Project of Hunan Province （CX2014B302）, National Key Laboratory Cultivation Base Construction Project （15KFXM09）, the National Science-Technology Support Plan Projects of China （2012BAI29B04）, The talent introduction Science Foundation of Hunan Agricultural University （13YJ09）, and the Natural Science Foundation of Hunan Province （2016JJ4040）.
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe res...
关键词：Macleaya cordata genome Benzylisoquinoline alkaloids Secondary metabolism SANGUINARINE CHELERYTHRINE Isotopic labeling 
Residue Study for a Standardized <i>Macleaya cordata</i>Extract in Growing-Finishing Swine被引量：2
《Open Journal of Animal Sciences》2017年第2期93-104,共12页Lu Zhao Ray A. Matulka Sophie von Alvensleben Mauro Morlacchini 
The aim of this study was to assess the effects of Sangrovit®, a standardized preparation of Macleaya cordata extract (MCE), on the health status and retained residues in growing-finishing swine. A total of twelve...
关键词：Macleaya cordata EXTRACT SWINE SANGUINARINE TOLERABILITY Residues 
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