CHELERYTHRINE

作品数：13被引量：88H指数：5
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相关领域：医药卫生更多>>
相关作者：李晶莹李红杨世杰孙巍徐超更多>>
相关机构：吉林大学北京市神经外科科研究所中国药科大学福建师范大学更多>>
相关期刊：《American Journal of Analytical Chemistry》《Medicinal Plant》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金中国博士后科学基金更多>>
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应对可转移多黏菌素耐药性--饲料添加剂来源的白屈菜红碱具有双重效应
《Engineering》2024年第1期163-173,共11页Huangwei Song Xueyang Wang Muchen Zhang Zhiyu Zou Siyuan Yang Tian Yi Jianfeng Wang Dejun Liu Yingbo Shen Chongshan Dai Zhihai Liu Timothy R.Walsh Jianzhong Shen Congming Wu Yang Wang 
grants from the Laboratory of Lingnan Modern Agriculture Project(NT2021006 to Yang Wang and Jianzhong Shen);the National Natural Science Foundation of China(81861138051 and 81991535 to Yang Wang and Congming Wu).
The emergence and spread of the mobile colistin-resistance gene,mcr-1,and its variants pose achallenge to the use of colistin,a last-resort antibiotic used to treat severe infections caused by extensively drug-resista...
关键词：CHELERYTHRINE Antibiotic adjuvant Conjugation inhibitor COLISTIN mcr-1 Dual effects 
Stability of Sanguinarine and Chelerythrine in Macleaya cordata (Willd.) R. Br.被引量：1
《Medicinal Plant》2019年第6期20-23,共4页Chunmei LI Xu CHEN Wenlan LI Bingmei LIU Li WANG Yubin JI 
Supported by Post-doctoral Foundation Project of Heilongjiang Province(LBHZ16094);Special Research Fund Project for Scientific and Technological Innovation Talents in Harbin City(2017RAQXJ115);Doctoral Starting up Project of Harbin University of Commerce(2019DS114).
[Objectives]To explore the stability of sanguinarine and chelerythrine in Macleaya cordata(Willd.)R.Br.[Methods]The solubility and stability of sanguinarine and chelerythrine in seven solvents were measured by HPLC.Be...
关键词：Macleaya cordata(Willd.)R.Br. SANGUINARINE CHELERYTHRINE STABILITY 
Simultaneous Quantitative Determination of Nitidine, Chelerythrine and Sanguinarine Using HPTLC from Callus Extract of <i>Zanthoxylum rhetsa</i>
《American Journal of Analytical Chemistry》2018年第8期386-396,共11页Kavitha Perala Veeresham Ciddi 
Nitidine, Chelerythrine and Sanguinarine, all these three alkaloids are benzophenanthridine alkaloids. Nitidine was used as an anti-HIV, anti-malarial and anti-cancer. Chelerythrine had anti-cancer and anti-inflammato...
关键词：Nitidine CHELERYTHRINE SANGUINARINE HPTLC 
The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism被引量：24
《Molecular Plant》2017年第7期975-989,共15页Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng 
This work was supported by National Natural Science Foundation of China （31200615, 31600238）, Postgraduate Research and Innovation Project of Hunan Province （CX2014B302）, National Key Laboratory Cultivation Base Construction Project （15KFXM09）, the National Science-Technology Support Plan Projects of China （2012BAI29B04）, The talent introduction Science Foundation of Hunan Agricultural University （13YJ09）, and the Natural Science Foundation of Hunan Province （2016JJ4040）.
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe res...
关键词：Macleaya cordata genome Benzylisoquinoline alkaloids Secondary metabolism SANGUINARINE CHELERYTHRINE Isotopic labeling 
Chelerythrine chloride from Macleaya cordata induces growth inhibition and apoptosis in human gastric cancer BGC-823 cells被引量：8
《Acta Pharmaceutica Sinica B》2012年第5期464-471,共8页Zhengfu Zhang Ying Guo Lingwei Zhang Jianbin Zhang Xionghui Wei 
This work was supported by grant 20080430283 from the China Postdoctoral Science Foundation and Jiangxi Yongfeng Boyuan Industry Co.,Ltd.(Jiangxi,China).
This study aimed to investigate the ability of chelerythrine chloride(CHE),the main active ingredient of Macleaya cordata,to induce apoptosis in human gastric cancer BGC-823 cells.The results demonstrate that CHE inhi...
关键词：Macleaya cordata Chelerythrine chloride BGC-823 cells APOPTOSIS 
博落回中两个新苯并菲啶类异喹啉生物碱(英文)被引量：5
《中国天然药物》2012年第5期378-382,共5页冯锋 叶冯芝 李彩莲 柳文媛 谢宁 
supported by the Fundamental Research Funds for the Central Universities (No. ZJ10015 and No.JKP2011009)~~
目的:对中药博落回的化学成分进行研究。方法:依次采用阳离子交换树脂、硅胶、Sephadex LH-20 柱色谱法和重结晶等分离技术, 对博落回的生物碱进行分离。并运用多种光谱技术对所得生物碱的结构进行鉴定。结果:从博落回中分离并鉴定了 6...
关键词：博落回 苯并菲啶异喹啉生物碱 6α-iso-butanonyldihydrosanguinnarine 6α-iso-butanonyldihydrochelerythrine 
Chelerythrine chloride binding of guanosine in aqueous solution被引量：3
《Chinese Chemical Letters》2009年第1期66-70,共5页Fan Liu Jian Bin Zhang Zheng Fu Zhang Xiao Yan Zhang Zuo Peng Du Xiong Hui Wei 
This project is financed by Jiangxi Boyuan Industry Co.,Ltd.(Jiangxi province,China)
In this work, the interaction between chelerythrine （CHE） and guanosine is studied using UV-vis and fluorescence measurements at various temperatures. The UV-vis spectra show that the increasing guanosine concentrat...
关键词：Chelerythrine （CHE） GUANOSINE UV-vis spectra Fluorescence spectra 
蒺藜皂苷对缺血心肌细胞内核转录因子-κB的作用被引量：10
《中草药》2008年第6期889-892,共4页孙巍 李晶莹 李红 杨世杰 
国家自然科学基金资助项目(30472020)
目的研究蒺藜皂苷对培养大鼠乳鼠心肌细胞H2O2损伤时心肌细胞内蛋白激酶C(PKCε)、细胞外信号调节激酶(ERK1/2)及核转录因子-κB(NF-κB)水平的影响。方法利用培养的Wistar大鼠乳鼠心肌细胞,采用H2O2建立心肌细胞损伤模型,应用PKCε抑制...
关键词：蒺藜皂苷 PKCΕ ERK1/2 核转录因子-kB(NF-kB) CHELERYTHRINE 
A spectral study of the interaction between chelerythrine chloride and cytidine被引量：2
《Chinese Chemical Letters》2007年第6期722-725,共4页Xiao Yan Zhang Quan Ling Suo Xiong Hui Wei 
To study the possible anticancer mechanisms of chelerythrine (CHE), and its interactions with cytidine were investigated by UV–vis spectrophotometric and spectrofluorimetric measurements and by thermodynamic calculat...
关键词：CHELERYTHRINE CYTIDINE Fluorescence quenching UV THERMODYNAMIC 
Interaction of Chelerythrine Choloride in Acid Buffer with Calf-thymus DNA被引量：5
《Chinese Chemical Letters》2006年第5期691-694,共4页Yah Jing SU Xiong Hui WEI 
The binding of chelerythrine （CHE） iminium to calf-thymus （CT） DNA is characterized by hypochromism and bathochromism in the absorption band, enhancement of fluorescence intensity, increase in fluorescence polariz...
关键词：CHELERYTHRINE CT-DNA INTERCALATION thermodynamic. 
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