supported by the National Natural Science Foundation of China(22271197,21905176);the Natural Science Foundation for Distinguished Young Scholars of Guangdong Province(2020B1515020011);the Science and Technology Plan of Shenzhen(JCYJ20190808142403590,JCYJ20190808153415062);the Instrumental Analysis Center of Shenzhen University。
The development of new and efficient polymerization strategies for the synthesis of multisubstituted fused heterocyclic polymers with attractive properties is of great significance.Herein,a rhodium-catalyzed polyannul...
supported by the National Science Fund for Distinguished Young Scholars (52125305);the National Natural Science Foundation of China (51873156,52173289);the Shanghai Science and Technology Committee (20dz1101200);the key project of the first demonstration project (Artificial Intelligence) of interdisciplinary joint research of Tongji University (ZD-11-202151)
Cellular metabolism in multiple organelles utilizes compartmentalized multienzyme efficient catalysis to realize substance metabolism, energy conversion and immune defenses. The convenient and biomimetic design of art...
supported by the National Natural Science Foundation of China (51933011, 31971296);the Key Areas Research and Development Program of Guangzhou (202007020006, 2019B020235001);the Natural Science Foundation of the Guangdong Province (2021A1515011799);the Opening Project of State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University (201922);the Science and Technology Project of Yantian District in Shenzhen City, Guangdong Province, China (20190106)。
The dense desmoplastic stroma and immunosuppressive microenvironment of pancreatic cancer hinder the penetration of drugs and induce a considerable resistance to conventional chemoradiotherapy. Although nanomedicine h...
This work was supported by the National Natural Science Foundation of China(21871260,22071242);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB20000000);Fujian Natural Science Foundation(2018J05035);the China Postdoctoral Science Foundation(2018M630734);the Science and Technology Research Program of the Education Department of Jiangxi Province(GJJ1991151).
Four types of unprecedented and chemodivergent reactions betweenα-diketones and alkynylα-diketones have been achieved under the catalysis of phosphine and Br?nsted base,respectively,leading to the rapid construction...
supported by the National Natural Science Foundation of China(21705038,21705043,21890744,21705037,21521063);the National Key R&D Program of China(2019YFA0210100);Natural Science Foundation of Hunan Province(2018JJ3029,2018JJ3092);China Postdoctoral Science Foundation(2020M672470);the Open Funding Project of Shandong Key Laboratory of Biochemical Analysis(QUSTHX201808)。
Artificial enzyme cascade systems with confinement effect are highly important in synthetic biology and biomedicine.Herein,a framework nucleic acid-based confined enzyme cascade(FNA-CEC)for synergistic cancer therapy ...
supported by the National Natural Science Foundation of China(21635005,21605083,21974064);the National Research Foundation for Thousand Youth Talents Plan of China,Specially-appointed Professor Foundation of Jiangsu Province,Program for innovative Talents and Entrepreneurs of Jiangsu Province。
Array based detection techniques with fluorescence signal reading is a powerful tool for multiple targets analysis. However,when applied fluorescence array for micro RNA detection, time-consuming multi-steps surface s...
supported by the National Natural Science Foundation of China(21831002,21801039);Ten Thousand Talents Program,the Jilin Province Natural Science Foundation(20160519003JH);the Fundamental Research Funds for the Central Universities(2412018QD007)
During the past few years, with the rapid development of mild methods for the generation of radical species, great progress in radical cascade reactions of unsaturated C–C bonds has been made. Many radical cascade re...
supported by the National Science Foundation of China (21572122, 21376146);Shaanxi Innovative Team of Key Science and Technology (2013KCT-17);the Fundamental Research Funds for the Central Universities (GK201703019, GK 201601005)
The ruthenium-catalyzed intermolecular cascade cyclization of aromatic acids with aromatic aldehydes, which involves the direct insertion of C–H bond into a polar C=O bond and the successive intramolecular nucleophil...
Supported by the National Natural Science Foundation of China (Grant Nos. 20621062 & 20872156)
3-Alkyl isocoumarins are provided by CuI/amino acid-catalyzed Sonogashira coupling reaction of o-bromo benzoic acids and terminal alkynes and the subsequent additive cyclization. This cascade process allows synthesis ...
the Youth Scientist Excellency Foundation (Grant No. 29625101), National Natural Science Foundation of China (Grant No. 29731010), Rhodia Rare Earth Co., the State Key Basic Research Program and Education Committee Foundation of Yunnan Province (Grant No
Under 216 nm UV-excitation, cascade emission of Pr3+ occurs from1S0 state in LaBaB9O16:Pr3+ that converts a single UV photon of high energy into two visible photons. The observation of the cascade emission in this oxi...