OXYSOPHORIDINE

作品数：4被引量：7H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Journal of Pharmaceutical and Biopharmaceutical Research》《Neural Regeneration Research》《中国药理通讯》更多>>
相关基金：国家自然科学基金更多>>
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Microbial synthesis of anti-tumor agent oxysophoridine through one step by filamentous fungus
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第2期48-52,共5页Qingfeng Meng Xuan Zhou Xu Ran Song Yan Shaobin Fu 
Sophoridine and oxysophoridine are alkaloids extracted from Chinese traditional medicinewith significant antitumor activities. Computer-aided design and preliminary structure-activity relationship studiesshowed that t...
关键词：BIOTRANSFORMATION ALKALOID FUNGUS natural product condition optimization 
Protective effect of oxysophoridine on cerebral ischemia/reperfusion injury in mice被引量：5
《Neural Regeneration Research》2013年第15期1349-1359,共11页Hongbo Wang Yuxiang Li Ning Jiang Xiaoping Chen Yi Zhang Kuai Zhang Tengfei Wang Yinju Hao Lin Ma Chengjun Zhao Yanrong Wang Tao Sun Jianqiang Yu 
supported by the National Natural Science Foundation of China, No. 30960506, 81160524;the Natural Science Foundation of Ningxia Hui Autonomous Region, No. NZ11212;the Key Scientific Research Project of Ningxia Hui Autonomous Region Health Department, No. 2012152;the Project of Ningxia Medical University, No. XM2011017
Oxysophoridine, a new alkaloid extracted from Sophora alopecuroides L., has been shown to have a protective effect against ischemic brain damage. In this study, a focal cerebral ischemia/reperfusion injury model was e...
关键词：neural regeneration traditional Chinese medicine brain injury OXYSOPHORIDINE ischemia/reperfusion injury oxidative stress N-methyI-D-aspartate receptor NEUROPROTECTION grants-supported paper NEUROREGENERATION 
Oxysophoridine Suppresses the Growth of Hepatocellular Carcinoma in Mice:In Vivo and cDNA Microarray Studies被引量：2
《Chinese Journal of Integrative Medicine》2012年第3期209-213,共5页姚小青 张韵慧 龙伟 刘培勋 
Supported by Tianjin Key Technology Research & Development Program(No.07ZCKFSH00200)
Objective：To observe the in vivo effects of oxysophoridine on hepatocellular carcinoma in mice and to study the related mechanisms.Methods：C57BL mice were inoculated with mouse hepatoma H22 cells subcutaneously,then...
关键词：OXYSOPHORIDINE hepatocellular carcinoma cDNA microarray QRT-PCR Tnfrsf11b OSTEOPROTEGERIN 
The Effect and Mechanism of Oxysophoridine on Central Nervous System
《中国药理通讯》2005年第4期19-19,共1页Jiang Yuanxue Yu Jianqiang 
关键词：神经系统 中枢神经 显微镜 药理学 
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