Bisphenol A(BPA)is an endocrine disruptor present in polycarbonate plastics used in food containers and water bottles that resists insulin action and leads to type 2 diabetes mellitus(T2DM).However,there is scant rese...
Supported by the Beijing Municipal Natural Science Foundation:To Explore the Effect of Acupotomy on Subchondral Bone Remodeling in Early and Middle KOA Based on OPG/RANKL/RANK pathway(7192110)
OBJECTIVE:To investigate the effects of acupotomy on inhibiting abnormal formation of subchondral bone in rabbits with knee osteoarthritis(KOA).METHODS:A total of 24 New Zealand rabbits were randomly divided into four...
Supported by Hainan Province Major Program of Science and Technology Projects 2017,No.ZDKJ2017007.
BACKGROUND Gestational diabetes mellitus(GDM)raises the risk of high blood pressure and may cause a series of life-threatening complications in pregnant women.Screening and management of GDM and gestational hypertensi...
Objective:To observe the clinical efficacy of heat-sensitive moxibustion plus medications on senile osteoporosis(SOP),and to explore the related mechanisms.Methods:A total of 70 elderly participants with osteoporosis ...
Background: High blood pressure is associated with adverse morphological and functional changes in the cardiovascular system, including left ventricular hypertrophy (LVH). Osteoprotegerin (OPG) is a member of the tumo...
This work was supported by grants from the National Natural Science Foundation of China(81270902,81381220308,and 30230380).
Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes,yet the mechanisms are not completely understood.Here,we demonstrated that serum LPS levels were significantly higher in newly diagno...
Objective To investigate the correlation between decoyreceptor ( DcR) 1,DcR2,osteoprotegerin ( OPG) gene polymorphisms and susceptibility of Crohn's disease(CD) in Han population in Zhejiang province. MethodsFrom Apri...
Supported by the National Natural Science Foundation of China(No.31271336)~~
Objective This study aimed to verify the association between osteoprotegerin gene (OPG) and its variants with osteoporosis (OP) by performing integrative analysis.Methods We used the KGG software to perform gene-based...
National Natural Science Foundation of China(81301532);Shanxi Returned Overseas Students'Scientific Research Foundation Project(2017-119);Shanxi Key Research and Development Program(Guidelines)Project(201603D321074);Shanxi Overseas Students'Scientific and Technological Activities Selective Foundation Project in 2017.
Objective: To investigate the curative efficacy of vitamin D3 in combination with tripterygium wilfordii polyglycoside in patients with rheumatoid arthritis (RA) and its influences on indices of bone restoration. Meth...
Background Bone remodeling is a lifelong process due to the balanced activity of osteoclasts (OCs),the bone-reabsorbing cells,and osteoblasts (OBs),and the bone-forming cells.This equilibrium is regulated by numerous ...