TRIPTERYGIUM

作品数：85被引量：186H指数：7
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相关领域：医药卫生更多>>
相关作者：龚建光金娟何强马朝俊张忠祥更多>>
相关机构：浙江省人民医院北京协和医学院中国药科大学四川省中药研究所更多>>
相关期刊：《Chinese Medical Sciences Journal》《Chinese Journal of Cancer Research》《Traditional Medicine Research》《Journal of Traditional Chinese Medicine》更多>>
相关基金：国家自然科学基金北京市自然科学基金更多>>
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Effect of moxibustion on expression profile of miRNAs in Tripterygium glycoside-induced decreased ovarian reserve
《Journal of Traditional Chinese Medicine》2024年第4期745-752,共8页SHEN Jie YIN Yaoli LI Hongxiao LU Ge ZHU Yaoyao QIN Yantong JIN Xun CHENG Jie SHEN Meihong 
the National Natural Science Foundation of China:Based on Phosphatidylinositol-3-kinase/Protein kinase B Signaling Pathway Study microRNAs Regulating Mechanism of Moxibustion Improve Ovarian Function(No.81804179);to Explore the miRNA Mechanism of Acupuncture and Moxibustion Against Oxygen Stress in Improving Ovarian Function based on Nuclear Factor Erythropoietin-2-related Factor 2/AU-rich Element Pathway(No.81774408);to Explore the Effect and Molecular Mechanism of Moxibustion on Granulosa Cells in Premature Ovarian Failure based on"Autophagy-apoptosis Cross-talk"(No.81973957)。
OBJECTIVE:To explore the possible regulatory mechanism of microRNA(miRNA)in moxibustion treatment for decreased ovarian reserve(DOR).METHODS:The DOR model was constructed by intragastrical Tripterygium glycoside suspe...
关键词：ovarian reserve MOXIBUSTION MICRORNAS mechanics 
Efficiency and safety of Tripterygium Wilfordii Hook F for IgA nephropathy: an update systematic review and meta-analysis
《Pharmacology Discovery》2024年第2期24-31,共8页Zi-Yi He Hui-Chuan Tian Yan Zhao Rui-Yu Mou Hong-Wei Yuan 
supported by the Foundation.The authors are grateful to Dr.Jia Yingjie for his help with the preparation of the ideas in this paper.
Background:Immunoglobulin A Nephropathy(IgAN)currently stands as the most prevalent primary chronic glomerular disease worldwide.The latest guidelines recommend the application of renin-angiotensin system inhibitors(R...
关键词：TRIPTERYGIUM IgA nephropathy systematic review META-ANALYSIS 
Prediction of potential targets and molecular mechanisms of Tripterygium hypoglaucum for oral lichen planus based on network pharmacology and molecular docking
《Journal of Hainan Medical University》2023年第24期33-42,共10页MEI Jie SUN Yu WANG Zheng-an KUANG Hui-fang ZENG Xiao-mei CAI Hongxuan FU Qi-ya LUO Wen 
National Natural Science Foundation of China(82360190);Hainan Natural Science Foundation(No.822RC828);Hainan Provincial Department of Education Research Project(No.Hnky2018ZD-7)。
Objective:To explore the potential targets and molecular mechanisms of tripterygium hypoglaucum for oral lichen planus(OLP)by applying network pharmacology and molecular docking technology.Methods:The active ingredien...
关键词：Tripterygium hypoglaucum Oral lichen planus Network pharmacology Molecular docking MECHANISM 
Tripterygium hypoglaucum extract ameliorates adjuvant-induced arthritis in mice through the gut microbiota被引量：2
《Chinese Journal of Natural Medicines》2023年第10期730-744,共15页HU Jianghui NI Jimin ZHENG Junping GUO Yanlei YANG Yong YE Cheng SUN Xiongjie XIA Hui LIU Yanju LIU Hongtao 
supported by the Health Commission of Hubei Province of China(No.ZY2021Z005);the Major Science and Technology Project in Yunnan Province(No.202102AE090042)。
Traditionally,Tripterygium hypoglaucum(Levl.)Hutch(THH)are widely used in Chinese folk to treat rheumatoid arthritis(RA).This study aimed to investigate whether the anti-RA effect of THH is related with the gut microb...
关键词：ARTHRITIS Gut microbiota IMMUNITY INFLAMMATION Tripterygium hypoglaucum 
Liangxue Xiaoban decoction and its disassembled prescriptions ameliorate psoriasis-like skin lesions induced by imiquimod in mice via T cell regulation
《Journal of Traditional Chinese Medical Sciences》2022年第4期409-419,共11页Feifei Tang Shuling Liu Fafeng Cheng Qingguo Wang Xueqian Wang 
This experimental study was supported by the Key Research Project of the Beijing University of Chinese Medicine(2020-JYBZDGG-023);Young Qihuang Scholars Project(90020163320001).
Objective:To explore the therapeutic capacity of the Liangxue Xiaoban(LXXB)decoction and its disassembled prescriptions in the modulation of T cell subsets and recurrence-related indexes of psoriasis using a psoriasis...
关键词：PSORIASIS T cells Recurrence Liangxue Xiaoban decoction Disassembled prescription Tripterygium glycoside 
Integrating systematic pharmacology-based strategy and experimental validation to explore mechanism of Tripterygium glycoside on cholangiocyte-related liver injury被引量：6
《Chinese Herbal Medicines》2022年第4期563-575,共13页Yajing Li Sen Li Xiaoyong Xue Ting Wang Xiaojiaoyang Li 
supported by grants from Beijing Nova Program of Science&Technology(Grant No.Z191100001119088 to XL);Beijing Municipal Science&Technology Commission(Grant No.7212174 to XL);National Natural Science Foundation of China(Grant No.82004045 to XL);Young Talents Promotion Project of China Association of Traditional Chinese Medicine(Grant No.2020-QNRC2-01 to XL);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(Grant No.ZYYCXTD-C-202006 to XL)。
Objective:Tripterygium glycoside(TG)is widely used in clinical practice for its multiple bioactivities including anti-inflammatory and immunosuppressive effects.However,emerging studies have frequently reported TG-ind...
关键词：cell apoptosis CHOLANGIOCYTE liver injury Tripterygium glycoside TRIPTOLIDE 
Identification of a cytochrome P450 from Tripterygium hypoglaucum(Levl.)Hutch that catalyzes polpunonic acid formation in celastrol biosynthesis被引量：2
《Chinese Journal of Natural Medicines》2022年第9期691-700,共10页CHEN Xiao-Chao LU Yun LIU Yuan ZHOU Jia-Wei ZHANG Yi-Feng GAO Hai-Yun LIDan GAO Wei 
supported by the National Key R&D Program of China(No.2020YFA0908000);the National Natural Science Foundation of China(Nos.81773830 and 81973418);the Key Project at Central Government Level:the ability establishment of sustainable use for valuable Chinese medicine resources(No.2060302-1806-03),and the National Program for Special Support of Eminent Professionals.
Tripterygium hypoglaucum(Levl.)Hutch,a traditional Chinese medicinal herb with a long history of use,is widely distributed in China.One of its main active components,celastrol,has great potential to be developed into ...
关键词：Tripterygium hypoglaucum Cytochrome P450 Polpunonic acid CELASTROL BIOSYNTHESIS 
Research review on the main chemical constituents and pharmacological effects of Tripterygium hypoglaucum (Levl.) Hutch.
《Asian Journal of Traditional Medicines》2022年第3期94-107,共14页Yunfei Ai Shuhui Dong Xiaoxiao Huang Shaojiang Song 
Tripterygium hypoglaucum(Levl.)Hutch.(THH),which belongs to Tripterygium genus of Celastraceae family,is widely used as the common Chinese herbal medicine.It has been reported that the chemical constituents of T.hypog...
关键词：Tripterygium hypoglaucum. chemical constituents pharmacological effects REVIEW 
Efficacy of Bushen Culuan decoction(补肾促卵方)on ovarian follicle and follicular granulosa cells in mice with premature ovarian insufficiency induced by tripterygium wilfordii polyglycoside被引量：2
《Journal of Traditional Chinese Medicine》2022年第1期23-29,共7页MA Kun YUAN Yuan CHEN Yanxia YUAN Bochao WANG Kaili TIAN Caidie LI Jiani 
Supported by Chinese Traditional Medicine“One Belt One Road”International Cooperation Project of China Academy of Chinese Medical Science(No.GH-2017-02-02)。
OBJECTIVE:To investigate the protective efficacy of Bushen Culuan decoction补肾促卵方,BCD)on ovarian follicle and follicular granulosa cells in mice with premature ovarian insufficiency(POI)induced by tripterygium wil...
关键词：primary ovarian insufficiency TRIPTERYGIUM granulosa cells APOPTOSIS Bushen Culuan decoction 
Role of oxidative stress in anti-cancer activity of Tripterygium wilfordii被引量：1
《Traditional Medicine Research》2021年第6期3-7,共5页Li-Ping Yang Jian Hao Dan Chen 
Introduction Oxidative stress,a characteristic of tumor cells,is defined as a relative excess of reactive oxygen species(ROS),directly associated with cancer.Although excessive ROS can cause oxidative damage,ROS withi...
关键词：DAMAGE TRIPTERYGIUM ACUTE 
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