AGONISTS

作品数：136被引量：373H指数：10
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相关机构：北京大学中国医科大学中国科学院北京中医药大学更多>>
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CRX-527 as a candidate adjuvant in a recombinant BCG-based malaria vaccine被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2024年第1期1-7,共7页Nor Munirah Zakaria Muhammad Adamu Abbas Rapeah Suppian 
supported by the Ministry of Higher Education Malaysia for Fundamental Research Grant Scheme with Project Code:FRGS/1/2021/SKK06/USM/002/4.
Objective:To investigate the role of CRX-527,a Toll-like receptor 4 agonist,as the possible adjuvant for recombinant Mycobacterium bovis Bacillus Calmette-Guerin expressing merozoite surface protein 1C(BCG-MSP-1C).Met...
关键词：CRX-527 BCG BCG-MSP-1C TLR-4 agonists Cytokine IgG MALARIA 
Small molecule-based immunomodulators for cancer therapy被引量：10
《Acta Pharmaceutica Sinica B》2022年第12期4287-4308,共22页Yinrong Wu Zichao Yang Kui Cheng Huichang Bi Jianjun Chen 
This work was supported by the National Natural Science Foundation of China(No.82173668);Scientific Research Project of High-Level Talents(No.C1034335,China)in Southern Medical University of China;Thousand Youth Talents Program(No.C1080094,China)from the Organization Department of the CPC Central Committee,China.
Immunotherapy has led to a paradigm shift in the treatment of cancer.Current cancer immunotherapies are mostly antibody-based,thus possessing advantages in regard to pharmacodynamics(e.g.,specificity and efficacy).How...
关键词：Cancer immunotherapy Small molecules IMMUNOMODULATORS INHIBITORS AGONISTS 
The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer's disease: agonists or antagonists?被引量：1
《Neural Regeneration Research》2015年第2期205-207,共3页Rubina Marzagalli Alessandro Castorina 
Alzheimer＇s disease （AD） is the most common neurodegenerative disorder, and its incidence is relatively high among elderly people, affecting about 1-2% of the population between 60-65 years old and rising dramatica...
关键词：The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer’s disease agonists or antagonists 
Synthesis of 2-(Benzodioxol-2-yl)acetic Acids as PPARδAgonists
《Chinese Chemical Letters》2006年第8期1013-1016,共4页Jian Lei KANG Zhi Bing ZHENG Dan QIN Li Li WANG Song LI 
supported by the National High Technology Research and Development Program of China(863 project:2003AA235010);the National Natural Science Foundation of China(No.30472092).
A new series of compounds, 2-（benzodioxol-2-yl）acetic acids, have been synthesized. Their structures were confirmed by MS and 1H-NMR. The preliminary pharmacological screening showed that these compounds exhibited p...
关键词：PPARδ agonists 2-（benzodioxol-2-yl）acetic acids synthesis. 
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