supported by NSFC(22371008),BNLMS;Laboratory for Synthetic Chemistry and Chemical Biology of Health@InnoHK of ITC,HKSAR.
Furans bearing alkynyl substituents are highly useful in organic synthesis.However,the methodologies to access these important furan derivatives are rather limited.We herein report an efficient synthesis of alkynylate...
supported by the National Natural Science Foundation of China(21871094);the Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine[(2014)No.32];We also thank the support of the Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation(No.2021CL04).
Here is an operable and rare strategy for copper-initiated radical dearomative 2,5-alkylarylation of furan. By means of this strategy, we realized the dearomatization of furans to construct spirooxindoles with good yi...
We acknowledge the National Natural Science Foundation of China(No.21472136)for financial support.
Main observation and conclusion The reaction of 2-alkynylanisoles/sulfides with SOCl_(2) and DMSO was conducted to conveniently furnish the biologically interesting 3-(methylthio)-benzo[b]furans/thiophenes via intramo...
o-Carboryne (1,2-dehydro-o-carborane) is a very useful synthon for the synthesis of a variety of carborane-functionalized molecules. Diels-Alder reaction of o-carboryne with furans gave a series of carborane-fused o...
supported by the Natural Science Foundation of Guangdong Province(No.10151022501000033).
A magnetic nano-supported Cu(I)catalyst was prepared and showed high activity for cyclization of ene-yne-ketone to synthesize furans.The catalyst was easily recovered from the reaction by using external magnets and re...
Cytotoxic styryl lactone, ( + )-7-epi-Goniofufurone (1), has been prepared with a new route from 3-O-benzyl-1, 2-O-isopropylidene-5-C-phenyl-β-L-ido-pentofuranose (6), a derivative of (+)-glucose. Treatment of 14 wit...