supported by grants from the National Natural Science Foundation of China(No.31872675);Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2020-KF02).
Main observation and conclusion An HPLC-UV-guided separation was performed and four pairs of unprecedented macathiohydantoin dimers,lepithiohydimerins A—D(1—4)bearing a rare disulfide bond were isolated from the tub...
National Natural Science Foundation of China(Grant No.20972005)
Various amino acid esters were reacted with different isothiocyanates in alkaline Al2O3 at room temperature for 1 h affording thiohydantoins in moderate to excellent yields.
A novel kind of acetohydroxyacid synthase(AHAS) inhibitors, arylsulfonylaminocarbonyl-2-thiohydantoins, was synthesized based on biorational design. The structures of these compounds were confirmed by IR, MS, NMR, a...