SPIRO

作品数：171被引量：144H指数：5
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相关作者：李福民陈冲郑小璐石东王杰更多>>
相关机构：电子科技大学河南大学合肥工业大学武汉大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划国家高技术研究发展计划更多>>
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Synthesis of spirocyclopropylpyrazole derivatives via the cascade reaction of alkylidenecyclopropanes with pyrazolidinones and trifluoroethanol
《Organic Chemistry Frontiers》2022年第5期1410-1416,共7页Mengyang Shen Yuanshuang Xu Xinying Zhang Xuesen Fan 
We are grateful to the National Natural Science Foundation of China(U2004189);the Central Plains Science and Technology Innovation Leader Project(224200510009);the Program for Innovative Research Team in Science and Technology in Universities of Henan Province(20IRTSTHN005);the Natural Science Foundation of Henan Province(212300410364);the Henan Key Laboratory of Organic Functional Molecules and Drug Innovation;the 111 Project(D17007)for financial support.
A novel synthesis of spirocyclopropylpyrazole derivatives tethered with a trifluoromethyl unit through an unprecedented cascade reaction of alkylidenecyclopropanes with pyrazolidinones and trifluoroethanol(TFE)has bee...
关键词：ALKYL ETHANOL SPIRO 
One-pot synthesis of natural-product inspired spiroindolines with anti-cancer activities
《Organic Chemistry Frontiers》2022年第3期682-686,共5页Shi-Qiang Li Wei Yan Liu-Jun He Ming Zhang Dian-Yong Tang Hong-yu Li Zhong-Zhu Chen Zhi-Gang Xu 
The authors would like to thank the Science and Technology Research Program of Chongqing Municipal Education Commission(CXQT19029 and KJZD-M201801301);Science&Technology Department of Sichuan Province(2017FZ0084);the Natural Science Foundation Project of CQ CSTSC(cstc2018jszx-cyzdX0023 and cstc2021jcyj-bsh0233).We would also like to thank Ms H.Z.Liu and J.Xu for obtaining the HRMS and NMR data.
A post-Ugi/diastereoselective cascade reaction was developed to construct naturally existing spiroindolines via a facile and metal-free one-pot protocol.During the construction,a new C-C bond was formed through a sele...
关键词：synthesis SPIRO CENTERS 
Synthesis of functionalized 3,2’-pyrrolidinyl spirooxindoles via domino 1,6-addition/annulation reactions of para-quinone methides and 3-chlorooxindoles
《Organic Chemistry Frontiers》2022年第3期615-626,共12页Xiaochen Tian Yongxing Zhang Weiwu Ren Yang Wang 
We are thankful for financial support from OUC,QNLM(LMDBCXRC201902,LMDBCXRC201903),tsqn201909056,tsqn202103152.The project is supported by the Fundamental Research Funds for the Central Universities.
A highly efficient base-mediated diastereoselective[4+1]cycloaddition of ortho-tosylaminophenyl-substituted p-QMs with 3-chlorooxindoles has been developed to afford 3,2’-pyrrolidinyl spirooxindoles in high yields wi...
关键词：DOMINO functional SPIRO 
Diastereodivergent synthesis of fully disubstituted spiro[indoline-3,2’-pyrrolidin]-2-ones via tuneable Lewis base/Brønsted base-promoted(3+2)cycloadditions
《Organic Chemistry Frontiers》2022年第1期19-24,共6页Ke Li Zhipeng Zhang Jiahui Zhu Yuxin Wang Jing Zhao Er-Qing Li Zheng Duana 
the National Natural Science Foundation of China(21702189,21672193,and 21272218);the Key Scientific and Technological Project of Henan Province(202102310004);the China Ministry of Industry and Information Technology(Z135060009002);Zhengzhou University(JC21253007)of China for financial support of this research.
Herein we report a diastereodivergent synthesis of fully disubstituted spiro[indoline-3,2’-pyrrolidin]-2-ones through base-promoted(3+2)cycloadditions.Importantly,the catalysts are found to have full control over the...
关键词：BASE stereo substituted 
Efficient enantioselective synthesis of CF_(2)Hcontaining dispiro[benzo[b]thiophene-oxindolepyrrolidine]s via organocatalytic cycloaddition被引量：1
《Organic Chemistry Frontiers》2022年第1期210-215,共6页Yabo Deng Yongzhen Li Yalan Wang Shuo Sun Sichao Ma Pengfei Jia Wenguang Li Kairong Wang Wenjin Yan 
the National Natural Science Foundation of China(no.81872723 and 82073679).
An efficient and practical organocatalytic asymmetric[3+2]cycloaddition of difluoromethylated ketoimines and methyleneindolinones catalyzed by a quinine-derived squaramide has been disclosed.Under mild conditions,a br...
关键词：CATALYTIC CENTERS SPIRO 
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