云南高校图书馆联盟文献共享服务平台- PREPULSE

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Pharmacological characterization of JWX-A0108 as a novel type Ⅰ positive allosteric modulator of a7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model: 《Acta Pharmacologica Sinica》2019年第6期737-745,共9页Li-lan Sun Tao-yi Yang Ning-ning Wei Wei Lu Wen-xuan Jiao Qi-qi Zhou Yong-zhen Miao Qin Gao Xin-tong Wang Qi Sun KeWei Wang; research grants to KWW and Q S from the National Natural Science Foundation of China (NSFC 81573410,31370741, and 21572011);Ministry of Science and Technology of China (2013CB531302).; The a7 nicotinic acetylcholine receptor (a7 nAChR) is a ligand-gated Ca^2+-permeable homopentameric ion channel implicated in cognition and neuropsychiatric disorders. Pharmacological enhancement of a7 nAChR function ...; 关键词：a7 NACHR positive ALLOSTERIC modulator thiazolyl HETEROCYCLIC derivative JWX-A0108 electrophysiology PREPULSE inhibition of ACOUSTIC STARTLE spatial working memory cognitive deficits

Prepulse inhibition deficits in antipsychotic-na-ve first-episode schizophrenia:a meta-analysis: 《Journal of Translational Neuroscience》2018年第2期23-34,共12页Yanbing Xiong Xianbin Li Zhen Mao Lei Zhao Yilang Tang Chuanyue Wang; supported by researchgrants from the National Natural Science foundationof China (81471365, 81601169); Major Brain Program of Beijing Science and Technology Plan (Z161100002616017);Beijing Municipal Administration of Hospitals ClinicalMedicine Development of Special Funding Support(ZYLX201807).; Objective:Published studies have found prepulse inhibition(PPI)in schizophrenia is impaired,suggesting PPI may be a biomarker of schizophrenia.We aim to examine whether PPI deficits exist in antipsychotic-na-ve,first-...; 关键词：PREPULSE inhibition(PPI) antipsychotic-na-ve FIRST-EPISODE SCHIZOPHRENIA patients META-ANALYSIS

Aberrant Light-Induced Depression is Associated with Impaired Sensorimotor Gating in Mice: 《World Journal of Neuroscience》2018年第1期1-9,共9页Toshiaki Haga Junichi Toei Kenichi Mitsui Mareki Ohtsuji Yo Kodera Kenichi Osada Hiroyuki Nishimura; Mice subjected to an irregular light-dark cycle are known to lose their capacity to synchronize their behavioral rhythm to environmental light, and to show endophenotypes related to depressive disorders. Here we obser...; 关键词：DEPRESSION SENSORIMOTOR Gating C3H/HeJ PREPULSE Inhibition CIRCADIAN Rhythm

No Correlation between <i>AVPR</i>1A Promoter Polymorphisms and Prepulse Inhibition in Patients with Nocturnal Enuresis: 《Open Journal of Nephrology》2014年第1期20-27,共8页Sebastian Schulz-Juergensen Philipp von Bismarck René Santer Paul Eggert; Introduction: A correlation between AVPR1A promoter polymorphisms and prepulse inhibition (PPI) of startle reflexes has been described in healthy adults. Many children with nocturnal enuresis (NE) have a reduced PPI a...; 关键词：AVPR1A Promoter PREPULSE Inhibition NOCTURNAL ENURESIS CORRELATION

Optimization of 4.7-keV X-ray titanium sources driven by 100-ps laser pulses被引量：1: 《Chinese Physics B》2013年第6期454-458,共5页熊俊董佳钦贾果王瑞荣王伟傅思祖郑无敌; An experiment with thin titanium foils irradiated by two pulses delayed in time is conducted on the bnenguang-Il laser facility. A prepulse induces an underdense plasma, 2-ns later a main pulse （λL ≈ 0.35 μm, EL ...; 关键词：X-ray source PREPULSE titanium foil

Influence of Laser Prepulse in Ultra-short Laser-Driven Proton Acceleration: 《Annual Report of China Institute of Atomic Energy》2011年第1期112-113,共2页LU Jian-xin, LAN Xiao-fei, XI Xiao-feng, WANG Lei-jian, HUANG Yong-sheng, YANG Da-wei, TANG Xiu-zhang (Department of Nuclear Technology Application); Influence of laser prepulse in ultra-short laser-driven proton acceleration was investigated by the differences in spatial distribution and energy spectrum between different foil-targets. The laser system produced pul...

Chronic morphine treatment decreases acoustic startle response and prepulse inhibition in rats被引量：1: 《Science China(Life Sciences)》2010年第11期1356-1360,共5页MENG ZhiQiang1,3, ZHOU DongMing1,2, WANG JianHong1 & MA YuanYe1,2 1State Key Laboratory of Brain and Cognitive Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China 3Graduate University of Chinese Academy of Sciences, Beijing 100049, China; supported by the National Natural Science Foundation of China (Grant Nos.30470553, 30770700 and 30530270);National High-Tech Research and Development Program of China (Grant No. O7013810);Major State Basic Research Development Program of China (Grant Nos.2005CB522803 and 2007CB947703);Yunnan Science and Technology Program (Grant No.2006PT08-2); The reward-related effects of addictive drugs primarily act via the dopamine system, which also plays an important role in sensorimotor gating. The mesolimbic dopamine system is the common pathway of drug addiction an...; 关键词：MORPHINE TREATMENT SENSORIMOTOR gating STARTLE response PREPULSE inhibition

A New Discharge Scheme of a Prepulse Plus Two Main Pulses for Capillary-Discharge Soft-X-Ray Laser: 《Chinese Physics Letters》2007年第6期1580-1582,共3页栾伯晗赵永蓬王骐程元丽谢耀; Supported by the National High-Technology Research and Development Programme of China under Grant No 863-804-7- 10, the National Natural Science Foundation of China under Grant No 60608007, the Programme of Excellent Team in Harbin Institute of Technology, and the Development Programme for 0utstanding Young Teachers in Harbin Institute of Technology （HITQNJS.2006.023）.; Reducing the capillary-discharge current is one way of possibly decreasing the pumping power requirement. We examine the influence of various discharge currents on laser intensity and determine the suitable pre-discha...

Coupling coefficient enhanced by prepulse in laser plasma propulsion: 《Optoelectronics Letters》2006年第6期477-479,共3页ZHENG Zhi-yuan ZHANG Jie HAO Hui-ying ZHAO Chang-chun LU Xin LI Yu-tong; Compared with direct ablation,a prepulse is used to propulsion. It is found that the coupling coefficient is beam and the prepulse. At a delay time of 12 ns,the × 10^-5 N/W. enhance the coupling coefficient in laser ...; 关键词：耦合系数激光等离子推进预脉冲激光加热

Experimental investigation of Ne-like Ti X-ray laser: 《Science China Mathematics》1996年第6期631-636,共6页黄文忠尤永录淳于书泰张杰张启仁杨上金武德勇庄秀群谷渝秋刘淑萍杜凤英蔡玉琴袁晓东魏晓峰; The experiment on Ne-like X-ray laser has been carried out successfully at the Xingguang Laser Facility by means of a transmission-reflection line focus system and a prepulse 5 ns before the main pulse. The TiXIII los...; 关键词：X-ray laser Ne-tike TI IONS PREPULSE COLLISIONAL excitation.

PREPULSE