云南高校图书馆联盟文献共享服务平台- STARTLE

STARTLE: 作品数：11被引量：18H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：胡卢丰更多>>; 相关机构：温州医科大学更多>>; 相关期刊：《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《Open Journal of Acoustics》《Open Journal of Psychiatry》更多>>; 相关基金：国家自然科学基金温州市科技计划项目国家重点基础研究发展计划更多>>

Female Carriers of the Met Allele of the BDNF Val66Met Polymorphism Develop Weaker Fear Memories in a Fear-Potentiated Startle Paradigm: 《Journal of Behavioral and Brain Science》2022年第5期211-235,共25页Phillip R. Zoladz Mackenzie R. Riggenbach Jordan N. Weiser Jennifer J. Hipskind Leighton E. Wireman Kelsey L. Hess Tessa J. Duffy Julie K. Handel MacKenzie G. Kaschalk Kassidy E. Reneau Brianne E. Mosley; The val66met polymorphism of the bdnf gene, which is associated with compromised brain-derived neurotrophic factor (BDNF) signaling, impaired synaptic plasticity, and impaired learning, may increase one’s susceptibil...; 关键词：Fear Conditioning EXTINCTION POLYMORPHISM BDNF Val66Met STARTLE

Roles of 5-HT2 receptors in effects of DOM,ketamine and methamphetamine on prepulse inhibition in Sprague Dawley rats: 《中国药理学与毒理学杂志》2021年第9期669-670,共2页JIANG Kai-li LI Kai-xi LIU Xiao-yan SU Rui-bin; OBJECTIVE Prepulse inhibition(PPI)of the acoustic startle response provides a measure of sensorimotor gating system mecha⁃nisms,which is known to be impaired in schizo⁃phrenia patients.We assessed the effects of the 5...; 关键词：prepulse inhibition 5-HT2 receptor startle magnitude psychoactive substances

Pharmacological characterization of JWX-A0108 as a novel type Ⅰ positive allosteric modulator of a7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model: 《Acta Pharmacologica Sinica》2019年第6期737-745,共9页Li-lan Sun Tao-yi Yang Ning-ning Wei Wei Lu Wen-xuan Jiao Qi-qi Zhou Yong-zhen Miao Qin Gao Xin-tong Wang Qi Sun KeWei Wang; research grants to KWW and Q S from the National Natural Science Foundation of China (NSFC 81573410,31370741, and 21572011);Ministry of Science and Technology of China (2013CB531302).; The a7 nicotinic acetylcholine receptor (a7 nAChR) is a ligand-gated Ca^2+-permeable homopentameric ion channel implicated in cognition and neuropsychiatric disorders. Pharmacological enhancement of a7 nAChR function ...; 关键词：a7 NACHR positive ALLOSTERIC modulator thiazolyl HETEROCYCLIC derivative JWX-A0108 electrophysiology PREPULSE inhibition of ACOUSTIC STARTLE spatial working memory cognitive deficits

Finger or Light:Stimulation Sensitivity of Visual Startle in the Coma Recovery Scale-Revised for Disorders of Consciousness被引量：4: 《Neuroscience Bulletin》2018年第4期709-712,共4页Feng Zhou Hui Li Kai Wang Yanbin He Yan Chen Xiaoxiao Ni Yechun Guo Wei Lv Jiechun Zhang Qiuyou Xie Ronghao Yu; supported by the Guangdong Provincial Natural Science Foundation(2015A030313609);the Guangzhou Municipal Project for Science and Technology Foundation(201508020253); Dear Editor,Coma, the vegetative state （VS）, and the minimally- conscious state （MCS）, often collectively referred to as disorders of consciousness （DOCs）, typically occur after severe traumatic or non-traumatic...; 关键词：Finger or Light Stimulation Sensitivity of Visual Startle in the Coma Recovery Scale-Revised for Disorders of Consciousness TBI

抑制STAT3活化对GD2阳性乳腺癌干细胞自我更新能力的影响被引量：2: 《温州医科大学学报》2018年第2期110-114,共5页祝立和胡卢丰季剑乐朱暐; 温州市科技计划项目(Y20140485); 目的:探讨选择性STAT3抑制剂Stattic对GD2^+乳腺癌干细胞自我更新能力的影响。方法:运用流式细胞仪从乳腺癌细胞系MDA-MB-231中分选GD2^+乳腺癌干细胞;采用CCK-8、乳腺球形成实验鉴定GD2^+乳腺癌干细胞的增殖、自我更新能力;Western-blo...; 关键词：乳腺癌干细胞神经节昔脂GD2 信号传导与转录激活因子3 STARTLE 自我更新

Post-traumatic stress disorder risk and brain-derived neurotrophic factor Val66Met被引量：9: 《World Journal of Psychiatry》2016年第1期1-6,共6页Lei Zhang Xiao-Xia Li Xian-Zhang Hu; Supported by Center for the Study of Traumatic Stress,Department of Psychiatry,Uniformed Services University of the Health Sciences; Brain-derived neurotrophic factor(BDNF), which regulates neuronal survival, growth differentiation, and synapse formation, is known to be associated with depression and post-traumatic stress disorder(PTSD). However, t...; 关键词：POST-TRAUMATIC stress DISORDER BRAIN-DERIVED NEUROTROPHIC factor Depression BIOMARKER STARTLE

Sex Differences in the Effects of Sertraline and Stressors in Rats Previously Exposed to Restraint Stress: 《Journal of Biomedical Science and Engineering》2015年第7期399-419,共21页Ines Pereira-Figueiredo Juan Carro Luis J.Munoz Consuelo Sancho Orlando Castellano Ricardo Gomez-Nieto Dolores E.Lopez; supported by the University of Salamanca Research Support Grant 2015 to Dr.Dolores E.Lopez; The serotonergic system in the brain plays a major role in mood and anxiety regulation when exposed to stress. The aim of the present study was to evaluate the effects of Sertraline administration in coping with stres...; 关键词：Behavior HABITUATION PPI SEROTONIN STARTLE

Cued aversive classical conditioning in humans: The role of trait-anxiety: 《Open Journal of Psychiatry》2013年第2期230-237,共8页óscar Andión Xavier Caseras Miquel àngel Fullana Alberto Fernandez-Teruel Marc Ferrer Miquel Casas Rafael Torrubia; No study so far has specifically addressed the influence of individual differences in trait-anxiety on aversive classical conditioning as indexed by the startle reflex response. We compared the startle reflex response...; 关键词：Classical CONDITIONING STARTLE REFLEX Trait-Anxiety Cued CONDITIONING Fear-Potentiated STARTLE

5-HT<sub>2A</sub>Receptor Activation Normalizes Exaggerated Fear Behavior in <i>p</i>-Chlorophenylalanine (PCPA)-Treated Rats: 《Journal of Behavioral and Brain Science》2012年第4期454-462,共9页Cathryn R. Hughes Lee Tran N. Bradley Keele; Deficits in serotonin (5-hydroxytryptamine, 5-HT) neurotransmission are implicated in abnormal emotional behaviors such as aggression, anxiety, and depression. However, the specific 5-HT receptor mechanisms involved a...; 关键词：FEAR Conditioning STARTLE Reflex 5-HT2 DOI KETANSERIN SB 206553

Context Dependent Auditory Thresholds Determined by Brainstem Audiometry and Prepulse Inhibition in Mongolian Gerbils被引量：2: 《Open Journal of Acoustics》2012年第1期34-49,共16页Markus Walter Konstantin Tziridis Sonke Ahlf Holger Schulze; Information on hearing thresholds is not always reliable as differences in these thresholds have been described even for the same species. This may partially be due to different methods used by different labs. A frequ...; 关键词：Acoustic TRAUMA HEARING Thresholds AUDITORY Processing STARTLE Response

STARTLE