KETANSERIN

作品数：25被引量：14H指数：3
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相关领域：医药卫生更多>>
相关作者：苏定冯于辉缪朝玉程勇张黎明更多>>
相关机构：第二军医大学上海市药品不良反应监测中心安徽理工大学河南医科大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《中国医学生物技术应用》《Pharmacology & Pharmacy》《中国药理学通报》更多>>
相关基金：国家自然科学基金更多>>
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Baroreflex deficiency aggravates learning and memory disorders in rats
《中国药理学与毒理学杂志》2021年第9期649-650,共2页ZHU De-rong FENG Zhao-yang JI Wei QI Hui-bin KONG De-ping ZHANG Fang-fang YU Hai-yang GAO Yong-feng TAN Rui ZHAO Xiao-min 
Natural Science Foundation of Shandong Province(ZR2017MH048)。
OBJECTIVE Microglia M1/M2 po⁃larization play pro-inflammatory and anti-inflam⁃matory roles,respectively,which is involved in memory decline.There is a close relationship between impaired baroreflex function and memory...
关键词：arterial baroreflex learning and memory MICROGLIA POLARIZATION KETANSERIN 
Role of 5-HT2A Receptors in Immunomodulation in Animal Models of Aggressive Behavior
《Pharmacology & Pharmacy》2016年第8期313-320,共9页G. V. Idova E. L. Alperina E. N. Zhukova M. A. Cheido R. V. Kozhemyakina 
Serotonin 5-HT2A receptors are playing an important role in the pathophysiology of aggressive behaviors and in the control of immune function. In the present study, we analyzed the effects of activation and blockade o...
关键词：Aggressive Behavior Serotonin 5-HT2A Receptors DOI KETANSERIN IgM-Immune Response 
Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function
《中国药理学通报》2015年第B11期185-186,共2页
Aim Baroreflex dysfunction is associated with a higher rate of sudden death after myocardial infarction （MI）. Ketanserin enhances baroreflex function in rats. The present work was designed to examine whether ketan- ...
关键词：KETANSERIN myocardial INFARCTION BAROREFLEX angiogenesis α7-nAChR 
Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function被引量：3
《Acta Pharmacologica Sinica》2013年第12期1508-1514,共7页Jian-guang YU En-hui ZHANG Ai-jun LIU Jian-guo LIU Guo-jun CAI Ding-feng SU 
Aim： Baroreflex dysfunction is associated with a higher rate of sudden death after myocardial infarction （MI）. Ketanserin enhances baroreflex function in rats. The present work was designed to examine whether ketan...
关键词：KETANSERIN myocardial infarction BAROREFLEX ANGIOGENESIS a7-nAChR 
5-HT<sub>2A</sub>Receptor Activation Normalizes Exaggerated Fear Behavior in <i>p</i>-Chlorophenylalanine (PCPA)-Treated Rats
《Journal of Behavioral and Brain Science》2012年第4期454-462,共9页Cathryn R. Hughes Lee Tran N. Bradley Keele 
Deficits in serotonin (5-hydroxytryptamine, 5-HT) neurotransmission are implicated in abnormal emotional behaviors such as aggression, anxiety, and depression. However, the specific 5-HT receptor mechanisms involved a...
关键词：FEAR Conditioning STARTLE Reflex 5-HT2 DOI KETANSERIN SB 206553 
High extracellular potassium ion concentration attenuates the blockade action of ketanserin on Kv1.3 channels expressed in xenopus oocytes
《Chinese Medical Journal》2008年第24期2584-2591,共8页LIANG Zhen-tao WANG Xian-pei ZENG Qiu-tang LIAO Yu-hua ZOU An-ruo LI Lu TU Dan-na 
Background Ketanserin （KT）, a selective serotonin （5-HT） 2-receptor antagonist, reduces peripheral blood pressure by blocking the activation of peripheral 5-HT receptors. In this study electrophysiological method ...
关键词：KETANSERIN Kv1.3 potassium channel potassium ion IMMUNOMODULATION electrolytes imbalances channel kinetics 
Effects of low-dose ketanserin on blood pressure variability, baroreflex sensitivity and end-organ damage in spontaneously hypertensive rats
《第二军医大学学报》2006年第2期216-216,共1页
关键词：凯耳讷 血压变化 高血压 药物治疗 
Restoration of baroreflex function by ketanserin is not blood pressure dependent in conscious freely moving rats
《第二军医大学学报》2005年第3期289-289,共1页FuYJ ShuH MiaoCY WangMW SuDF 
Objective: Since the end of the 1980s. the pathological importance of baroreflex function has attracted the attention of many investigators. In our previous studies, it was found that ketanserin lowered blood pressure...
关键词：低血压 灵敏度 病理机制 小鼠 动物实验 
Restoration of baroreflex function by ketanserin is not blood pressure dependent in conscious freely moving rats
《第二军医大学学报》2005年第1期20-20,共1页FuYJ ShuH MiaoCY WangMW SuDF 
Objective: Since the end of the 1980s,the pathological importance of baroreflex function has attracted the attention of many investigators. In our previous studies, it was found that ketanserin lowered blood pressure(...
关键词：心血管疾病 病理学 知觉意识 血压 
Effects of long- term treatment with ketanserin on blood pressure variability and end- organ damage in spontaneously hypertensive rats
《第二军医大学学报》2004年第2期212-212,共1页DUWen-Min MIAOChao-Yu LIUJianGuo SHENFu-Ming YANGXiang-Qun SUDing-Feng 
It has been proposed that instability of blood pressure m ay produce organ damage.Ketanserin is an anti- hy- pertensive drug with an ability to reduce blood pressure variability(BPV) in acute experiments in spontaneou...
关键词：原发性高血压 鼠 实验 血压变化 器官损害 治疗 
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