CILIOPATHIES

作品数：4被引量：11H指数：2
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相关期刊：《Genes & Diseases》《Science China(Life Sciences)》《Biophysics Reports》《Journal of Genetics and Genomics》更多>>
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New insights into the roles for DYRK family in mammalian development and congenital diseases被引量：1
《Genes & Diseases》2023年第3期758-770,共13页Saishu Yoshida Kiyotsugu Yoshida 
supported by JSPS KAKENHI(No.21K06192 to S.Y.and 17H03584,18K19484,and 20H03519 to K.Y.);the Jikei University Research Fund(to K.Y.);the Takeda Science Foundation(to S.Y.);the Uehara Memorial Foundation(to S.Y.and K.Y.).
The dual-specificity tyrosine-regulated kinase (DYRK) family is evolutionarily conserved from invertebrate to mammals. DYRKs regulate cell proliferation, apoptosis, survival, and differentiation by modifying the prote...
关键词：CILIOPATHIES Development Down syndr ome DYRKS EMBRYOGENESIS 
The emerging role of tubulin posttranslational modifications in cilia and ciliopathies
《Biophysics Reports》2020年第4期89-104,共16页Kai He Kun Ling Jinghua Hu 
the National Institutes of Health(R01DK090038,1R01DK099160);P30 center grant(P30DK90728).
Tubulin posttranslational modifications(PTMs)add*tubulin code*to generate functional diversities of microtubules.Several types of tubulin PTMs accumulate on axonemes and basal bodies of cilia,including acetylation,glu...
关键词：Tubulin posttranslational modifications(PTMs) CILIA CILIOPATHIES ACETYLATION Glutamylation Glycylation 
Zebrafish as a Model for Human Ciliopathies被引量：7
《Journal of Genetics and Genomics》2016年第3期107-120,共14页Zhu Song Xiaoli Zhang Shuo Jia Pamela C.Yelick Chengtian Zhao 
supported by the grants from the National Natural Science Foundation of China (Nos. 31372274 and 31422051);Shandong Provincial Natural Science Foundation, China (No. JQ201506) to C.Z.;supported by the grant from NIH/NIDCR (R01DE018043) to P.C.Y.
Cilia, microtubule-based structures found on the surface of almost all vertebrate cells, play an array of diverse biological functions. Abnormal ciliary axonemal structure and function can result in a class of genetic...
关键词：CILIA ZEBRAFISH CILIOPATHY Disease model 
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