TETRODOTOXIN

作品数：22被引量：62H指数：4
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相关领域：医药卫生更多>>
相关作者：王洪允陈树桥顾谦群崔建洲宫庆礼更多>>
相关机构：中国海洋大学南京师范大学北京协和医院江苏吴中大自然生物工程有限责任公司更多>>
相关期刊：《南京师大学报（自然科学版）》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《Journal of Coastal Life Medicine》更多>>
相关基金：国家自然科学基金国家科技重大专项广东省自然科学基金国家重点基础研究发展计划更多>>
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Multiscale structural complexity analysis of neuronal activity in suprachiasmatic nucleus:Insights from tetrodotoxin-induced disruptions
《Chinese Physics B》2025年第4期605-613,共9页Ping Wang Changgui Gu Huijie Yang 
Project supported by the National Natural Science Foundation of China(Grant Nos.12275179,11875042,and 12150410309);the Natural Science Foundation of Shanghai(Grant No.21ZR1443900).
The suprachiasmatic nucleus in the hypothalamus is the master circadian clock in mammals,coordinating physiological processes with the 24-hour day–night cycle.Comprising various cell types,the suprachiasmatic nucleus...
关键词：suprachiasmatic nucleus circadian rhythm COMPLEXITY synchrony multiscale structural complexity 
Adaptive evolution of scn4aa in Takifugu and Tetraodon
《Aquaculture and Fisheries》2024年第5期745-752,共8页Hexing Wu Yonglai Hu Jing Wang Xiaoling Gong Baolong Bao 
supported by National Natural Science Foundation of China (41176108);Key Innovation Project of Shanghai Education Commission (14zz145).
Tetrodotoxin(TTX)is a potent neurotoxin firstly discovered in the ovary of pufferfish.The genetic basis of voltage-gated sodium channel resistance to TTX has been widely studied,but it remains unclear in the evolution...
关键词：TETRODOTOXIN Voltage-gated sodium channel scn4aa Adaptive evolution PUFFERFISH 
Every breath you take:assessing metabolic costs of toxin resistance in garter snakes(Thamnophis)
《Integrative Zoology》2022年第4期567-580,共14页Haley A.MONIZ Molly A.RICHARD C.M.GIENGER Chris R.FELDMAN 
This work was approved by the UNR IACUC 00687(to CRF)and APSU IACUC 19.023(to CMG);This research was supported by a National Science Foundation grant IOS1355221(to CRF)and a generous gift from Ron Aryel.
Trait specialization often comes at the expense of original trait function,potentially causing evolutionary tradeoffs that may render specialist populations vulnerable to extinction.However,many specialized adaptation...
关键词：adaptation standard metabolic rate TETRODOTOXIN toxin-resistance TRADEOFF 
Adsorption of tetrodotoxin by flexible shape-memory polymers synthesized from silica-stabilized Pickering high internal phase emulsion
《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》2021年第10期805-818,共14页Hong-xiang OU Chen-xia GONG Hong-lai XUE Dong-sheng ZHOU Kai-jia LI Shu-cheng LIU 
Project supported by the National Natural Science Foundation of China(No.21878026);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX19_1798);the Jiangsu Province University Blue Project;the Project of Higher Education Reform in Jiangsu Province(No.2019JSJG022),China。
Flexible shape-memory polymers were synthesized by Pickering high internal phase emulsion(HIPE)polymerization and used to adsorb and separate tetrodotoxin(TTX)from an aqueous solution.SiO_(2)nanoparticles were used to...
关键词：Tetrodotoxin(TTX) SiO_(2) Imidazolium-modified bromobutyl rubber(IBR) Pickering high internal phase emulsion(HIPE) ADSORPTION 
Rapid Determination of Tetrodotoxin in Human Plasma by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry
《Chemical Research in Chinese Universities》2018年第6期905-911,共7页CHEN Weizhu ZHANG Yiping SUN Jipeng XIE Quanling HONG Zhuan YI Ruizao 
Supported by the National Key Research and Development Program of China(No.2016YFF0201104);the Construction of Public Service Platform for Research and Test of Marine Pilot Technology of China(No.Bhsfs009);the Project of Xiamen Southern oceanographic Center,China(No.16PFW008SF15).
A sensitive analytical method was developed to determine tetrodotoxin（TTX） in human plasma samples using protein precipitation, followed by ultra performance liquid chromatography（UPLC） analysis coupled with tande...
关键词：Tetrodotoxin(TTX) 11-DeoxyTTX Ultra performance liquid chromatography(UPLC)coupled with tandem mass spectrometry(MS/MS) PLASMA Protein precipitation 
Inhibitive effect of loureirin B plus capsaicin on tetrodotoxin-resistant sodium channel
《Journal of Traditional Chinese Medicine》2018年第6期842-852,共11页Chen Su Wan Ying Liu Xiangming Pan Xinxin 
Supported by the National Natural Science Foundation of China(No.81403186);National Science Foundation of Hubei Grants(No.2014CFB455)
OBJECTIVE: To investigate whether the effect of loureirin B plus capsaicin on tetrodotoxin-resistant(TTX-R) sodium channel.METHODS: By using whole-cell patch-clamp recordings, in acutely isolated dorsal root ganglion(...
关键词：Loureirin B CAPSAICIN TRPV cation CHANNELS Spinal nerve ROOTS Neurons TETRODOTOXIN Sodium CHANNELS 
Simultaneous identification and quantification of tetrodotoxin in fresh pufferfish and pufferfish-based products using immunoaffinity columns and liquid chromatography/quadrupole-linear ion trap mass spectrometry被引量：4
《Chinese Journal of Oceanology and Limnology》2017年第4期883-893,共11页郭萌萌 吴海燕 江涛 谭志军 赵春霞 郑关超 李兆新 翟毓秀 
Supported by the National Natural Science Foundation of China(No.41106109);the China National Food Safety Standards Development Project(No.ZHENGHE-2015-356)
In this study, we established a comprehensive method for simultaneous identification and quantification of tetrodotoxin （TTX） in fresh pufferfish tissues and pufferfish-based products using liquid chromatography/qua...
关键词：TETRODOTOXIN fresh pufferfish pufferfish-based product immunoaffinity column liquidchromatography/quadrupole-linear ion trap mass spectrometry 
Toxicity assessment and screening of tetrodotoxin in the oblong blowfish(Takifugu oblongus)from the Tamil Nadu Coast of Bay of Bengal,India被引量：6
《Asian Pacific Journal of Tropical Medicine》2017年第3期263-268,共6页Indumathi SM Khora SS 
Objective:To assess the toxicity of the pufferfish Takifugu oblongus,from Chennai coast,Tamil Nadu,India and to detect the presence of Tetrodotoxin(TTX).Methods:The toxicity was evaluated by mouse bioassay using Swiss...
关键词：Food intoxications Takifugu oblongus Mouse bioassay Tetrodo toxin GC-MS HPLC 
Ethanol inhibits histaminergic neurons in mouse tuberomammillary nucleus slices via potentiating GABAergic transmission onto the neurons at both pre- and postsynaptic sites
《Acta Pharmacologica Sinica》2016年第10期1325-1336,共12页Yu SUN Shi-yu JIANG Jian NI Yan-jia LUO Chang-rui CHEN Zong-yuan HONG Yuchio YANAGAWA Wei-min QU Lu WANG Zhi-li HUANG 
Acknowledgements This work was supported in part by grants-in-aid for scientific research from the National Basic Research Program of China （No 2015CB856401）, the National Natural Science Foundation of China （No 31530035, 31571103, 81420108015, 31471064, 31421091, 81171255, and 31271164）, the Shanghai Committee of Science and Technology （No 14JC1400900 and 13dz2260700）, and the Key Laboratory Program of the Education Commission of Shanghai Municipality （No ZDSYS14005）.
Aim： Ethanol, one of the most frequently used and abused substances in our society, has a profound impact on sedation. However, the neuronal mechanisms underlying its sedative effect remain unclear. In this study, we...
关键词：ETHANOL tuberomammillary nucleus histaminergic neurons GABA receptor IPSCs BICUCULLINE BACLOFEN TETRODOTOXIN 
Puffer fish poisoning:summary of case reports from Thailand
《Journal of Coastal Life Medicine》2015年第5期416-417,共2页Beuy Joob Viroj Wiwanitkit 
Puffer fish poisoning is a common seafood poisoning.The problem is due to tetradotoxin in puffy fish meat.It can be seen in many countries with seacoasts.The problem is resulted from tetradotoxin(TTX)in puffer fish me...
关键词：Puffer fish POISONING Thailand TETRODOTOXIN 
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