FOLLISTATIN

作品数:51被引量:135H指数:7
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Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1被引量:1
《Science China(Life Sciences)》2024年第3期475-487,共13页Hao-Xiang Yuan Ya-Ting Chen Yu-Quan Li Yan-Sheng Wang Zhi-Jun Ou Yan Li Jian-Jun Gao Meng-Jie Deng Yuan-Kai Song Li Fu Hong-Bo Ci Feng-Jun Chang Yang Cao Yu-Peng Jian Bi-Ang Kang Zhi-Wei Mo Da-Sheng Ning Yue-Ming Peng Ze-Long Liu Xiao-Jun Liu Ying-Qi Xu Jun Xu Jing-Song Ou 
supported by the National Key Research and Development Program of China(2021YFA0805100);the National Natural Science Foundation of China(81830013,81770241,81970363,82000362,92268202,81170271,81370370,81490531,81670392,81600382);the National Natural Science Foundation of China Distinguished Young Scholar Grant(81325001);“973 Project”from the Ministry of Science and Technology of China(2009CB522104);Guangdong Basic and Applied Basic Research Foundation,China(2019B1515120092);the Science and Technology Planning Project of Guangzhou,China(202103000016);the Changjiang Scholars Program from the Ministry of Education of China;the Sun Yat-sen University Clinical Research 5010 Program;the Program of National Key Clinical Specialties。
Cardiopulmonary bypass has been speculated to elicit systemic inflammation to initiate acute lung injury(ALI), including acute respiratory distress syndrome(ARDS), in patients after cardiac surgery. We previously foun...
关键词:cell-derived extracellular vesicles acute lung injury acute respiratory distress syndrome cardiopulmonary bypass follistatin-like protein 1 
Follistatin-Like 1单倍体敲除促进肺纤维化小鼠成纤维细胞自噬
《南开大学学报(自然科学版)》2023年第6期47-50,93,共5页姜芳馨 李霄鹤 宁文 
天津市应用基础研究联合项目(重点项目)(21JCZDJC00030);国家自然科学基金(81430001,31071241,31874160)。
Follistatin-like 1(Fstl1)是促纤维化因子,在成纤维细胞中通过调节TGF-β信号参与肺纤维化发生过程.自噬是维持细胞稳态的过程,在细胞衰老和分化中起到重要的作用.在特发性肺纤维化全肺中自噬不足.通过博来霉素处理Fstl1+/-和Fstl1+/+...
关键词:follistatin-like 1 成纤维细胞 自噬 
Higher Tolerance of Min Pigs Under Cold Stress:An Assessment from Reproduction Perspective
《Journal of Northeast Agricultural University(English Edition)》2022年第3期77-84,共8页Chen Wen-gui Guo Zhen-hua Liu Di Ma Hong Yang Yun-chun Islam MdSaiful Lv Lei Wang Wen-tao Zhang Dong-jie Peng Fu-gang 
Supported by the National Natural Science Foundation of China(32172696,U20A2052,31872980);Heilongjiang Provincial Scientific Research Business Fund Project(CZKYF2020A004,CZKYF2021-2-C025);Heilongjiang Provincial Natural Science Foundation(LH2019C064)。
Raising Min pigs(MPs)in northern China is challenging,because of harsh environmental conditions in winter.There is a hypothesis that MPs can tolerate cold stress better than Large White pigs(LWPs)and their oocyte comp...
关键词:cumulus-oocyte complexes FOLLISTATIN Large White pig Min pig SEASON 
Transcriptomic analysis elucidates the enhanced skeletal muscle mass, reduced fat accumulation, and metabolically benign liver in human follistatin-344 transgenic pigs被引量:3
《Journal of Integrative Agriculture》2022年第9期2675-2690,共16页LONG Ke-ren LI Xiao-kai ZHANG Ruo-wei GU Yi-ren DU Min-jie XING Xiang-yang DU Jia-xiang MAI Miao-miao WANG Jing JIN Long TANG Qian-zi HU Si-lu MA Ji-deng WANG Xun PAN Deng-ke LI Ming-zhou 
supported by grants from the National Key R&D Program of China(2020YFA0509500);the National Natural Science Foundation of China(U19A2036,32102512,31872335,and 31802044);the National Special Foundation for Transgenic Species of China(2014ZX0800605B);the Sichuan Science and Technology Program,China(2021YFYZ0009 and 2021YFYZ0030)。
Follistatin(FST) is an important regulator of skeletal muscle growth and adipose deposition through its ability to bind to several members of the transforming growth factor-β(TGF-β) superfamily, and thus may be a go...
关键词:FOLLISTATIN transgenic pig TRANSCRIPTOME skeletal muscle LIVER ADIPOSE 
Lentivirus-Mediated Short Hairpin RNA for Follistatin Downregulation Suppresses Tumor Progression in Hypopharyngeal Carcinoma被引量:1
《Current Medical Science》2022年第4期832-840,共9页Liang GE Shao-feng LIU 
supported by the Project of Young and Middle-aged Scientific Research Fund of Wannan Medical College(No.WK2019F11).
Objective:Follistatin(FST)inhibits the action of activin by interfering with the binding of activin to its receptor.Although the prognostic value of FST in various cancers has been investigated previously,studies rare...
关键词:FOLLISTATIN hypopharyngeal carcinoma migration INVASION PROLIFERATION apoptosis 
Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A-Smad2/3 in rats following myocardial infarction被引量:18
《Journal of Sport and Health Science》2021年第5期594-603,共10页Yue Xi Meili Hao Qiaoqin Liang Yongxia Li Da-Wei Gong Zhenjun Tian 
supported this research:The National Natural Science Foundation of China(No.31671240 to ZT,No.31900828 to YX).
Purpose:The aim of this study was to investigate the potential of dynamic resistance exercise to generate skeletal muscle-derived follistatin like-1(FSTL1),which may induce cardioprotection in rats following myocardia...
关键词:ANGIOGENESIS Follistatin like-1 Myocardial infarction Resistance exercise Signaling mechanism 
Association between follistatin-related protein 1 and the functional status of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis
《Chinese Medical Journal》2021年第10期1168-1174,共7页Taejun Yoon Sung Soo Ahn Jung Yoon Pyo Jason Jungsik Song Yong-Beom Park Sang-Won Lee 
supported by a faculty research grant from the Yonsei University College of Medicine(No.6-2019-0184);a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute,funded by the Ministry of Health and Welfare,Republic of Korea(No.HI14C1324)。
Background:Follistatin-like 1(FSTL1)plays both pro-inflammatory and anti-inflammatory roles in the inflammatory processes.We investigated whether serum FSTL1 could predict the current anti-neutrophil cytoplasmic antib...
关键词:Anti-neutrophil cytoplasmic antibody Follistatin-like 1 Functional status VASCULITIS 
鳜Follistatin基因cDNA的克隆及其胚胎发育表达分析被引量:3
《广西师范大学学报(自然科学版)》2020年第4期124-131,共8页胡姜丽 徐蕾 许艺兰 刘晶洁 孙悦 谢炎东 宾石玉 
国家自然科学基金(31560718)。
为探讨鳜Siniperca chuatsi卵泡抑素(Follistatin,FST)基因在胚胎发育时期的表达状况,本文采用qRT-PCR、3′RACE和5′RACE技术从鳜胚胎组织中克隆得到鳜FST基因的全长cDNA序列(GenBank登陆号:KM077175.1)为1271 bp。生物信息学分析表明,...
关键词: FST基因 克隆 胚胎发育 表达分析 
Follistatin Like 5 ( FSTL5) inhibits epithelial to mesenchymal transition in hepatocellular carcinoma被引量:2
《Chinese Medical Journal》2020年第15期1798-1804,共7页Deng-Yong Zhang Jia-Sheng Lei Wan-Liang Sun Dong-Dong Wang Zheng Lu 
the grants from the Anhui Province Science Foundation for Youths(No.1808085QH288);the University Top-notch Talent Cultivation Project(No.gxbjZD28);the Bengbu Medical College Science Foundation(No.BYKY1734ZD);the Science Foundation of the First Affiliated Hospital of Bengbu Medical College(No.Byyfykj201727).
Background:Epithelial to mesenchymal transition(EMT)is a key process in determining distant metastasis and intra-hepatic dissemination of hepatocellular carcinoma(HCC).Follistatin(FST)family members are considered to ...
关键词:Hepatocellular carcinoma Follistatin-related protein Epithelial to mesenchymal transition PROGNOSIS Disease-free survival 
Corrigendum: Follistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis Through the Transforming Growth Factor Beta 1/Mitogen-Activated Protein Kinase Signaling Pathway被引量:2
《Chinese Medical Journal》2020年第14期1764-1764,共1页
In the article titled,uFollistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis Through the Transforming Growth Factor Beta 1/Mitogen-Activated Protein Kinase Signaling Pathway5'published in pages 1917-1925,Is...
关键词:FOLLISTATIN FIGURE COR 
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