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DEGLYCOSYLATION: 作品数：4被引量：3H指数：1; 导出分析报告; 相关领域：生物学更多>>; 相关作者：贺明吉永华何慧琼杨宏天徐清更多>>; 相关机构：上海大学中国科学院上海生命科学研究院更多>>; 相关期刊：《Neuroscience Bulletin》《Acta Biochimica et Biophysica Sinica》《hLife》《BIOCELL》更多>>; 相关基金：国家自然科学基金更多>>

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Targeted protein editing technique in living mammalian cells by peptide-fused PNGase: 《hLife》2024年第11期576-591,共16页Min Wu Guijie Bai Ziyi Zhang Haixia Xiao Wenliang Sun Chaoguang Tian; supported by funding from the Key Project of the Ministry of Science and Technology of China(2018YFA0900500).; Various precise gene editing techniques at the DNA/RNA level,driven by clustered regularly interspaced short palindrome repeats(CRISPR)/CRISPR-associated protein 9(Cas9)technology,have gained significant prominence.Ye...; 关键词：N-glycosylated proteins peptide:N-glycanase(PNGase) protein-targeting peptides DEGLYCOSYLATION protein sequence editing protein degradation

20(R)-ginsenoside Rg3,a product of high-efficiency thermal deglycosylation of ginsenoside Rd,exerts protective effects against scrotal heat-induced spermatogenic damage in mice被引量：3: 《BIOCELL》2020年第4期655-669,共15页WEI LIU ZI WANG JING LENG HENG WEI SHEN REN XIAOJIE GONG CHEN CHEN YINGPING WANG RUI ZHANG WEI LI; the grants of the Jilin Science&Technology Development Plan(Nos.20170101011JC,20200301037RQ and 20190103092JH);the Open Fund of Key Laboratory of Biotechnology and Bioresources Utilization(KF202004).; Heat stress(HS)reaction can lead to serious physiological dysfunction associated with cardiovascular and various organ diseases.Ginsenoside Rg3(G-Rg3)is a representative component of ginseng rare saponin and can prote...; 关键词：20(R)-ginsenoside Rg3 Heat stress Spermatogenic damage Oxidative stress MAPK

Deglycosylation altered the gating properties of rNav1.3:glycosylation/deglycosylation homeostasis probably complicates the functional regulation of voltage-gated sodium channel: 《Neuroscience Bulletin》2008年第5期283-287,共5页徐清程慧雯何慧琼刘志睿贺明杨宏天周智磊吉永华; the National Basic Research Development Program of China (No. 2006CB500801).; Objective To examine the effect of deglycosylation on gating properties of rNav1.3. Methods rNav1.3 was expressed in Xenopus oocyte, with glycosylation inhibition by using tunicamycin. Two-electrode voltage clamp was ...; 关键词：rNav1.3 voltage-gated sodium channel GLYCOSYLATION two-electrode voltage clamp Xenopus oocyte

Influence of Substrate Conformation on the Deglycosylation of Ribonuclease B by Recombinant Yeast Peptide:N-glycanase: 《Acta Biochimica et Biophysica Sinica》2007年第1期8-14,共7页Shengjun WANG Peng George WANG and Qingsheng QI State Key Laboratory of Microbial Technology,Life Science Schooll,Shandong University,Jinan 250100,China; This work was supported by a grant from National Natural Science Foundation of China(No. 30470399); Peptide：N-glycanase has been thought to be responsible for proteasome-dependent degradation of misfolded glycoproteins translocated from the endoplasmic reticulum （ER） to the cytosol. Therefore, the enzyme was supp...; 关键词：glycanase ribonuclease B GLYCOPROTEIN DEGLYCOSYLATION circular dichroism

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