EXCITOTOXICITY

作品数:71被引量:272H指数:7
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相关领域:医药卫生更多>>
相关作者:于洋杨柳马春蕾孙晖王天佑更多>>
相关机构:滨州医学院北京市神经外科科研究所山东大学华东师范大学更多>>
相关期刊:《Chinese Journal of Integrative Medicine》《Frontiers in Biology》《Acta Pharmacologica Sinica》《International Journal of Ophthalmology(English edition)》更多>>
相关基金:国家自然科学基金国家教育部博士点基金国家重点基础研究发展计划湖北省自然科学基金更多>>
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Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration被引量:16
《Translational Neurodegeneration》2022年第1期917-930,共14页Manish Verma Britney N.Lizama Charleen T.Chu 
Glutamate is the most commonly engaged neurotransmitter in the mammalian central nervous system,acting to mediate excitatory neurotransmission.However,high levels of glutamatergic input elicit excitotoxicity,contribut...
关键词:Mitochondrial calcium Mitochondrial calcium uniporter NCLX antiporter Parkinson’s disease Alzheimer’s disease LRRK2 PINK1 BETA-AMYLOID MITOPHAGY EXCITOTOXICITY Amyotrophic lateral sclerosis Huntington’s disease GLUCOCEREBROSIDASE 
Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism被引量:2
《Translational Neurodegeneration》2017年第1期310-323,共14页Rafael Lazo-Gomez Ricardo Tapia 
This work was done under the auspice of Consejo Nacional de Ciencia y Tecnología(CONACyT,protocol approval number 240817);of Dirección General de Asuntos del Personal Académico(DGAPA),UNAM(protocol approval number IN204516).RLG is recipient of a CONACyT doctoral scholarship.
Background:Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders.Effective therapeutic strategies are an unmet need for these disorder...
关键词:Motor neuron disorder QUERCETIN RESVERATROL SIRTUIN EXCITOTOXICITY 
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