相关期刊:《Chinese Journal of Integrative Medicine》《Frontiers in Biology》《Acta Pharmacologica Sinica》《International Journal of Ophthalmology(English edition)》更多>>
Glutamate is the most commonly engaged neurotransmitter in the mammalian central nervous system,acting to mediate excitatory neurotransmission.However,high levels of glutamatergic input elicit excitotoxicity,contribut...
This work was done under the auspice of Consejo Nacional de Ciencia y Tecnología(CONACyT,protocol approval number 240817);of Dirección General de Asuntos del Personal Académico(DGAPA),UNAM(protocol approval number IN204516).RLG is recipient of a CONACyT doctoral scholarship.
Background:Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders.Effective therapeutic strategies are an unmet need for these disorder...