This work was supported by the National Key Research and Development Program of China(grant No.2021YFC2100600);National Natural Science Foundation of China(grant No.31830104);Science and Technology Commission of Shanghai Municipality(grant Nos.19JC1413000 and 19430750600)to L.B.We thank the Core Facility and Technical Service Center for SLSB and the Instrumental Analysis Center in SJTU for data collection.
Acarbose is a potent glycosidase inhibitor widely used in the clinical treatment of type 2 diabetes mellitus(T2DM).Various acarbose analogs have been identified while exploring compounds with improved pharmacological ...
Medicinal plants have been reported to play an important role in modulating glycemic responses and have preventive and therapeutic implications. The intestinal digestive enzymes play a vital role in the carbohydrate d...
the Institute of Science and Technology,Moutai Group(No.MTGF2021020),China.
Backgrounds:Tannic acid(TA),as a plant-derived phenolic substance,is involved in regulating the activity of starch digestive enzymes,but its underlying mechanism remains unclear.Methods and Results:In the present stud...
This research study was carried out as a part of DBT BULDER-SUK programme(PR No.BT/INF/22/SP43063/2022);sanctioned to Shivaji University,Kolhapur,MS,India.Also,the authors gratefully acknowledge STIC,Cochin for providing HR-TEM facility.
Owing to platinum's nobility,catalytic potential and vast range of possible biomedical applications,synthesis of platinum nanoparticles is attracting the attention of scientists worldwide.Though the plant mediated met...
Different anatomical parts of Dioscorea nipponica Makito have been used in foods and folk medicines for their nutritional and pharmacological properties;however,the scientific data on enzyme inhibitory activities and ...
the scholarship support provided to her by RMIT University.
Obesity is a prominent global public health challenge.This study is aimed to explore the inhibition properties of organic and aqueous extracts of Hibiscus sabdariffa against the major enzymes associated with obesity(...
The amylase obtained from Cladophora hutchinsiae was purified by the starch affinity method(11.4-fold and specific activity of 89.7±2.6 U/mg protein)and examined for its biochemical characterization,thermodynamic pro...
supported by the National Natural Science Foundation of China(Grant No.31901728);the Jiangsu Planned Projects for Postdoctoral Research Funds(2020Z297).
The interaction mechanism of mucin and α-amylase with virgin olive oil (VOO) polyphenols (oleuropein (OL),tyrosol (TY),hydroxytyrosol (HT)) was analyzed by fluorescence,ultraviolet (UV) absorption,attenuated total re...
Supported by Jahangirnagar University Annual Research Grant(Grant No.JU-ARG-2012-005).
Objective:To investigate the therapeutic effects of ethyl acetate extract of Mallotus repandus stem in α-amylase inhibitory activity(in vitro)and hypoglycemic activity in normal and glucose induced hyperglycemic rats...
In order to learn the enzymatic characteristics of Huai yam powder with medium-temperatureα-amylase, effects of substrate concentration,enzyme concentration, pH and temperature wereinvestigated. The Michealis-Menten ...