URINE

作品数:524被引量:923H指数:14
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相关作者:李宏森潘智文黄克建钟大放陈笑艳更多>>
相关机构:北京协和医院国家地质实验测试中心广西大学中国科学院更多>>
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Revolutionizing wearable healthcare with solid-state epidermal biomarker monitoring
《Science Bulletin》2024年第17期2650-2652,共3页Huarun Liang Yingying Zhang 
National Natural Science Foundation of China (52125201);Beijing Natural Science Foundation (Z240025)。
In modern medical research, the analysis of biomarkers in biofluids such as blood, urine, saliva, and sweat is indispensable for revealing human physiological processes and disease states[1-4]. However, existing detec...
关键词:URINE BLOOD wear 
Landscape of urine biomarkers for bladder cancer:molecular function,cell-of-origin,and bibliometric trend
《Oncology and Translational Medicine》2024年第3期132-142,共11页Min Liu Shuo Li Yuan Rong Fei Long Wu-Shi Zhao Yu-Xuan Qin Ting Wang Fu-Bing Wang Xiang-Yu Meng 
supported by the Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University(FBW,grant ZNJC202210);the CAMS Innovation Fund for Medical Sciences(FBW,grant 2022-I2M-C&T-B-118);the National Natural Science Foundation of China(XYM,grant 82303057);the Natural Science Foundation of Hubei Province of China(XYM,grant 2023 AFB521).
Background:The effective management of bladder cancer(BCa)depends on the early diagnosis and surveillance.Previous studies have explored numerous urinary molecules as potential biomarkers of BCa.However,the molecular ...
关键词:Bladder cancer Urine biomarker Molecular function Cell-of-origin BIBLIOMETRIC 
Graphene as adsorbent for highly efficient extraction of modified nucleosides in urine prior to liquid chromatography-tandem mass spectrometry analysis
《Chinese Chemical Letters》2024年第4期490-495,共6页Cheng Guo Xiaoxiao Zhang Xiujuan Hong Yiqiu Hu Lingna Mao Kezhi Jiang 
financially supported by National Natural Science Foundation of China (No.22176167);Fundamental Research Funds for the Central Universities (No.226-2023-00088);Key R&D Program of Zhejiang Province (No.2021C03125)。
RNA modifications have been involved in numerous biological processes, and aberrations of these modifications are tightly associated with various diseases including cancer. Herein, we developed graphenebased solid-pha...
关键词:Mass spectrometry RNA modification Modified nucleosides GRAPHENE BIOMARKER URINE 
Urine biomarkers discovery by metabolomics and machine learning for Parkinson’s disease diagnoses
《Chinese Chemical Letters》2023年第10期93-97,共5页Xiaoxiao Wang Xinran Hao Jie Yan Ji Xu Dandan Hu Fenfen Ji Ting Zeng Fuyue Wang Bolun Wang Jiacheng Fang Jing Ji Hemi Luan Yanjun Hong Yanhao Zhang Jinyao Chen Min Li Zhu Yang Doudou Zhang Wenlan Liu Xiaodong Cai Zongwei Cai 
support from the Collaborative Research Fund(No.C2011–21GF);from Guangdong Province Basic and Applied Basic Research Foundation(No.2021B1515120051).
Parkinson’s disease(PD)is a complex neurological disorder that typically worsens with age.A wide range of pathologies makes PD a very heterogeneous condition,and there are currently no reliable diagnostic tests for t...
关键词:Parkinson’s disease High-resolution mass spectrometry BIOMARKER METABOLOMIC Machine learning 
Diagnostic value of matrix metalloproteinases 2, 7 and 9 in urine for early detection of colorectal cancer
《World Journal of Gastrointestinal Surgery》2023年第5期931-939,共9页Liu Peng Xin Zhang Man-Li Zhang Tao Jiang Peng-Jun Zhang 
Supported by the National Key Research and Development Program of China,No.2020YFC2004604 and 2020YFC2002700.
BACKGROUND A noninvasive biomarker with high diagnostic performance is urgently needed for the early diagnosis of colorectal cancer(CRC).AIM To evaluate the diagnostic value of matrix metalloproteinases(MMPs)2,7 and 9...
关键词:Colorectal cancer Early detection Matrix metalloproteinases URINE BIOMARKER 
Intervention effect of Danbei Yifei formula on pulmonary fibrosis based on urine metabolomics by UHPLC-Q-Exactive
《Journal of Hainan Medical University》2022年第1期20-24,共5页Xiao-Jun Cai Bai-Hua Jiang Bi-Hai Zhang Zhen-Hua Lu Tao Wang Qiang Li Guan-Nan Jin 
Key Project of Heilongjiang Province(No.ZD2018019);Research and Development Planning Project of Applied Technology of Heilongjiang Province(No.GA19C108)。
Objective:Determine the urinary biomarkers and pathogenesis of pulmonary fibrosis rats,and elaborate the intervention mechanism of DanBei YiFei formula.Methods:Bleomycin was injected into the trachea to induce pulmona...
关键词:Danbei Yifei formula Pulmonary fibrosis LC-MS technology BIOMARKER Metabolic pathway 
Hepatocellular carcinoma biomarkers,an imminent need
《World Journal of Gastrointestinal Oncology》2021年第11期1847-1849,共3页S Pilar Zamora-Leon 
Hepatocellular carcinoma(HCC)is the most common malignant neoplasm of the liver and one of the deadliest cancers worldwide.The identification of novel,highly specific and more sensitive biomarkers for HCC is crucial b...
关键词:Hepatocellular carcinoma BIOMARKER BLOOD URINE FECES Gut microbiota 
Biomarkers for hepatocellular carcinoma based on body fluids and feces被引量:5
《World Journal of Gastrointestinal Oncology》2021年第5期351-365,共15页Ming-Cheng Guan Wei Ouyang Ming-Da Wang Lei Liang Na Li Ting-Ting Fu Feng Shen Wan-Yee Lau Qiu-Ran Xu Dong-Sheng Huang Hong Zhu Tian Yang 
Supported by National Natural Science Foundation of China,No.81972726,No.81871949 and No.81572345.
Novel non-/minimally-invasive and effective approaches are urgently needed to supplement and improve current strategies for diagnosis and management of hepatocellular carcinoma(HCC).Overwhelming evidence from publishe...
关键词:Hepatocellular carcinoma BIOMARKER BLOOD URINE FECES Gut microbiota 
Targeted metabolomics of sulfated bile acids in urine for the diagnosis and grading of intrahepatic cholestasis of pregnancy被引量:10
《Genes & Diseases》2018年第4期358-366,共9页Yuchao Li Xiaoqing Zhang Jianbo Chen Chengya Feng Yifan He Yong Shao Min Ding 
The present work was supported by the Chongqing Postdoctoral Science Foundation(Xm201313);National Natural Science Foundation of China(81471473);Research Fund for the Doctoral Program of Higher Education of China(20115503110013).
Intrahepatic cholestasis of pregnancy(ICP)is related to cholestatic disorder in pregnancy.Total urinary sulfated bile acids(SBAs)were found increased in ICP.We distinguished the metabolic profiling of urinary SBAs in ...
关键词:BIOMARKER HPLC-MS/MS Intrahepatic cholestasis of pregnancy Sulfated bile acids Targeted metabolomics URINE 
Association of Increased Urine Brain Derived Neurotrophic Factor with Lower Urinary Tract Symptoms in Men with Benign Prostatic Hyperplasia被引量:2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第4期531-535,共5页汪隆旺 李建龙 余义 肖瑞海 黄红卫 匡仁锐 海波 
supported by the Science and Technology Department of Jiangxi Province(No.20141BBG70036)
Urinary brain-derived neurotrophic factor(BDNF), an ubiquitous neurotrophin, was found to rise in patients with benign prostatic hyperplasia(BPH). We hypothesized that the urinary level of BDNF could be a potentia...
关键词:biomarker increased urine brain derived neurotrophic factor lower urinary tract symptoms benign prostatic hyperplasia 
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