CHEMOSENSITIZER

作品数：6被引量：9H指数：2
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相关领域：医药卫生更多>>
相关作者：吕立赖世英张雪梅张振蔚鲜于志群更多>>
相关机构：中山大学孙逸仙纪念医院华中科技大学同济医学院附属同济医院更多>>
相关期刊：《Science China(Life Sciences)》《Journal of Cancer Metastasis and Treatment》《Cancer Biology & Medicine》《中国药理学与毒理学杂志》更多>>
相关基金：国家自然科学基金广东省自然科学基金更多>>
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Targeting lncRNA16 by GalNAc-siRNA conjugates facilitates chemotherapeutic sensibilization via the HBB/NDUFAF5/ROS pathway被引量：2
《Science China(Life Sciences)》2024年第4期663-679,共17页Yanfang Liu Yan Wang Bing Liu Wenzhong Liu Yuanyuan Ma Yiren Cao Shi Yan Panpan Zhang Lixin Zhou Qimin Zhan Nan Wu 
supported by the National Natural Science Foundation of China (81972842, 82373082, 81988101, 82173152)
Chemoresistance is a significant barrier to effective cancer treatment.Potential mechanisms for chemoresistance include reactive oxygen species(ROS)accumulation and expression of chemoresistance-promoting genes.Here,w...
关键词：CHEMORESISTANCE lncRNARNA interference ROS CHEMOSENSITIZER 
VHH212 nanobody targeting the hypoxia-inducible factor 1α suppresses angiogenesis and potentiates gemcitabine therapy in pancreatic cancer in vivo被引量：3
《Cancer Biology & Medicine》2021年第3期772-787,共16页Guangbo Kang Min Hu He Ren Jiewen Wang Xin Cheng Ruowei Li Bo Yuan Yasmine Balan Zixuan Bai He Huang 
supported by grants from the National Key Research and Development Project(Grant No.2019YFA0905600);the Major State Basic Research Development Program of the Natural Science Foundation of Shandong Province in China(Grant No.ZR2020ZD11);the National Natural Science Foundation of China(Grant Nos.81772633 and 31470967);the Science and Technology Program of Tianjin,China(Grant No.19YFSLQY00110);the Taishan Scholars Program of Shandong Province。
Objective:We aimed to develop a novel anti-HIF-1αintrabody to decrease gemcitabine resistance in pancreatic cancer patients.Methods:Surface plasmon resonance and glutathione S-transferase pull-down assays were conduc...
关键词：Pancreatic cancer nanobody therapeutic intracellular antibody HIF-1αinhibitor GEMCITABINE CHEMOSENSITIZER 
Cancer immunity and therapy using hyperthermia with immunotherapy, radiotherapy, chemotherapy, and surgery被引量：3
《Journal of Cancer Metastasis and Treatment》2017年第1期218-230,共13页Yohsuke Yagawa Keishi Tanigawa Yasunobu Kobayashi Masakazu Yamamoto 
Hyperthermia is a type of medical modality for cancer treatment using the biological effect of artificially induced heat.Even though the intrinsic effects of elevated body temperature in cancer tissues are poorly unde...
关键词：HYPERTHERMIA cancer immunity CHEMOSENSITIZER RADIOSENSITIZER combination cancer therapy hyperthermic intraoperative peritoneal chemotherapy 
γ-生育三烯酚可能用做新型胃癌化疗增敏剂(英文)
《中国药理学与毒理学杂志》2015年第S1期11-12,共2页GautamSETHI 
Gamma-tocotrienol,a member of vitamin E superfamily has attracted great attention of late for its anti-proliferative and anti-carcinogenic potential against different cancers.For example,our group had previously repor...
关键词：GASTRIC cancer gamma-tocotrienol CHEMOSENSITIZER 
Using ^(99m)Tc-MIBI to Evaluate the Effects of Chemosensitizer on P-glycoprotein in Multidrug-resistant Carcinoma Cells
《The Chinese-German Journal of Clinical Oncology》2005年第2期83-85,共3页张振蔚 张雪梅 吴华 赵明 鲜于志群 周健 赖世英 
To establish a method to evaluate the effects of chemosensitizer onP-glycoprotein using ^(99m)Tc-MIBI, and observe the changes of ^(99m)Tc-MIBI uptake kinetics andP-glycoprotein levels after using verapamil in MDR hum...
关键词：multidrug resistance CHEMOSENSITIZER breast tumor P-GLYCOPROTEIN ^(99m)Tc-MIBI 
Sensitizing　effects　of　aradio－　and　chemo－sensitizer，metronidazol　amino　acidum　natrium（CMNa）被引量：1
《Journal of Medical Colleges of PLA(China)》1994年第2期93-97,共5页孟祥顺 赵芳 高建国 朱勤 郑秀龙 由慧萍 马煌如 
Radio-and chemo-sensitizing effects of a new sensitizer, metronidazol amino acidum natrium (CMNa), were studied by the methods of cell surviving fraction (in viiro), tumor growth delay (in vivo) and clinical observati...
关键词：RADIOSENSITIZER CHEMOSENSITIZER metronidazol AMINO acidum NATRIUM (CMNa) esophageal NEOPLASMS lung NEOPLASMS human 
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