MORPHOGEN

作品数：4被引量：17H指数：2
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相关领域：生物学医药卫生更多>>
相关机构：新疆医科大学更多>>
相关期刊：《Frontiers in Biology》《World Journal of Gastroenterology》《International Journal of Biomathematics》《Cell Research》更多>>
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Mathematical analysis on a multidimensional model of morphogen transport with receptor synthesis
《International Journal of Biomathematics》2014年第5期67-81,共15页Hongwei Yin Xiaoyong Xiao Xiaoqing Wen Tianshou Zhou 
In biological development, morphogens are locally produced and spread to other regions in organs, forming gradients that control the inter-related pattern and growth of developing organs. Mechanisms of morphogen trans...
关键词：WELL-POSEDNESS morphogen transport ENDOCYTOSIS receptor synthesis. 
Liver zonation: Novel aspects of its regulation and its impact on homeostasis被引量：5
《World Journal of Gastroenterology》2014年第26期8491-8504,共14页Rolf Gebhardt Madlen Matz-Soja 
Supported by Bundesministerium für Forschung und Technologie(BMBF)in the framework of the Systems Biology initiative"Virtual Liver Network",No.0315735
Liver zonation, the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids, is fundamental for proper functioning of this organ. Recent progress in elucidating localizatio...
关键词：HOMEOSTASIS LIVER Metabolic zonation Metabolism Morphogen signalling Optimization Pathology Regulatory network SINUSOID Systems biology 
Drosophila embryo syncytial blastoderm cellular architecture and morphogen gradient dynamics： Is there a correlation？
《Frontiers in Biology》2012年第1期73-82,共10页Aparna SHERLEKAR Richa RIKHY 
During embryo development in many metazoan animals, the first differentiated cell type to form is anepithelial cell. This epithelial layer is modified by developmental cues of body axes formation to give rise to vario...
关键词：morphogen gradient DROSOPHILA SYNCYTIUM EMBRYO cellular architecture 
Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus被引量：12
《Cell Research》2011年第10期1436-1451,共16页Yanyan Zhang Feifei Mao Yi Lu Wenqing Wu Lei Zhang Yun Zhao 
We thank Dr Jin Jiang （University of Texas Southwestern Medical Center at Dallas, USA）, Dr Robert Holmgren （Northwestern University, USA）, the ARIAD Pharmaceuticals and Developmental Studies Hybridoma Bank at the university of Iowa for reagents. We thank Dr Xiaochen Wang （National Institute of Biological Sciences, China）, Dr Min Wu （Wuhan University, China） and Dr Zhaocai Zhou （Institute of Biochemistry and Cell Biology, CAS, China） for critical comments on the manuscript. This work was supported by grants from the National Natural Science Foundation of China （30623003, 30971647 and 30971646）, the National Key Scientific Program of China （2011 CB943902 and 2010CB912100）, Shanghai Pujiang Program （09PJ1410900） and also from the ＂Strategic Priority Research Program＂ of the Chinese Academy of Sciences （XDA01010405 and XDA01010406）. Y Z and L Z are the scholars of the Hundred Talents Program of the Chinese Academy of Sciences.
The Hedgehog （Hh） family of secreted proteins is essential for development in both vertebrates and invertebrates. As one of main morphogens during metazoan development, the graded Hh signal is transduced across the ...
关键词：Cubitus interruptus DROSOPHILA FUSED HEDGEHOG MORPHOGEN 
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