funded by the National Natural Science Foundation of China(42277425,42161134001,U22A20614);“the Fundamental Research Funds for the Central Universities”,Nankai University(63171109);sponsored by Tianjin Health Research Project(TJWJ2023MS028);Tianjin Science and Technology planning project(21JCZDJC00330);National Clinical Key Discipline Cohort Study Project(GJZDZKZBDL 2022-);Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-043A);Ministry of Education,China(T2017002).
The thyroid is an essential endocrine organ in human body,and thyroid hormones(THs)are pivotal signaling molecules and mediators in various physiological processes.THs,particularly in their free form,play a critical r...
A multiple hormonal imbalance that accompanies heart failure(HF)may have a significant impact on the clinical course in such patients.The non-thyroidal illness syndrome(NTIS),also referred to as euthyroid sick syndrom...
This study was supported by the Chinese National Natural Science Foundation(Grant Nos.31970771,82071396,81771345);the Shaanxi Provincial Key R&D Foundation(Grant Nos.2021ZDLSF03-09);the Science and Technology Projects of Ningxia Autonomous Region Key R&D Programs(2018BFG02017);the Natural Science Foundation of Ningxia Province,China(Grant Nos.2020AAC03397);the Fundamental Research Funds for the Central Universities(Grant Nos.GK202007022,GK202105002,TD2020039Y,2020CSLZ009,2021CSZL008).
The lack of targeted and high-efficiency drug delivery to the central nervous system(CNS)nidus is the main problem in the treatment of demyelinating disease.Extracellular vesicles(EVs)possess great promise as a drug d...
Data from recent studies revealed that kidney diseases might affect the thyroid function in various ways. A variety of alterations in thyroid hormone levels and metabolism have also been reported in patients with chro...
Supported by Science and Technology Support Projects in Biomedicine Field of Shanghai Science and Technology Commission,No.19441907500;Naval Medical University Military Medical Innovation,No.2017JS07;Science and Technology Action Innovation Program by Science and Technology Commission of Shanghai,No.17411950104
BACKGROUND Post-stroke cognitive impairment(PSCI)is not only a common consequence of stroke but also an important factor for adverse prognosis of patients.Biochemical indicators such as blood lipids and blood pressure...
Background: FT3 levels in plasma may provide a marker for liver status in cirrhosis. Aim: The aim is to correlate thyroid functions with hepatic status in compensated and decompensated cirrhosis, and to study their ef...
The thyroid hormones(THs), triiodothyronine(T3) and thyroxine(T4), are essential for survival; they are involved in the processes of development, growth, and metabolism. In addition to hyperthyroidism or hypothyroidis...
Objective To explore the effect and mechanism of osteoprotegerin on apoptosis in human umbilical vein endothelial cells(HUVECs)induced by triiodothyronine(T3)with different concentrations.Methods HUVECs were cultured ...
Background:Graves'ophthalmopathy(GO)occurs commonly in children with Graves'disease(GD).However,there are limited studies on the clinical manifestations and thyroid autoantibodies in pediatric GO.The aim of this study...