Introduction: Intramuscular depot betamethasone treatment had resulted in a significant improvement among fibromyalgia patients with elevated C-reactive protein (C-RP) levels. Here, we wanted to evaluate the same regi...
funded by Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)[project number 439669440 TRR319 RMaP TP C01/C03 to M.H.TP B05 to M.-L.W.].
In a recent study published in Cell,Zhou et al.1 have characterized a highly unusual behavior of specialized stress granules(SG),driven by metabolism of UV-damaged pre-mRNA.These cytoplasmic SGs are characterized by a...
In markets for beef and sheep meat,an appropriate level of intramuscular fat(IMF)is highly desirable for meat-eating quality,but strategies to improve it usually lead to an undesirable excess in carcase fat,presenting...
This study was supported by National Natural Science Foundation of China(Grant Nos.81925036,China);the Key Research and Development Program of Science and Technology Department of Sichuan Province(Grant No.2020YFS0570,China);111 project(Grant No.B18035,China).
Recent clinical studies have shown that mutation of phosphatase and tensin homolog deleted on chromosome 10(PTEN)gene in cancer cells may be associated with immunosuppressive tumor microenvironment(TME)and poor respon...
Objective:Real-word data on long-acting luteinizing hormone-releasing hormone(LHRH)agonists in Chinese patients with prostate cancer are limited.This study aimed to determine the real-world effectiveness and safety of...
NIDDK(DK120430,DK121336,USA)to Danny Hung-Chieh Chou;JDRF(5-CDA-2020-947-A-N,USA)to Matthew J.Webber。
Aggregation represents a significant challenge for the long-term formulation stability of insulin therapeutics.The supramolecular PEGylation of insulin with conjugates of cucurbit[7]uril and polyethylene glycol(CB[7]-...
Financial support was provided by the National Key Research and Development Program of China(No.2020YFA0210800);the Key Technologies R&D Program of Henan(No.212102310231);the Academic Key Research Projects of Henan(Nos.21A430006 and 22A310010);the Major Project of Science and Technology of Fujian Province(No.2020HZ06006);the National Natural Science Foundation of China(Nos.22277011 and 22107019).
The ascendant danger of bacterial infections has resulted in an urgent requirement for developing new antibacterial approaches.Recently,nitric oxide(NO)has shown a broad-spectrum antimicrobial activity while avoiding ...
The "Five Hua" operation of skid block is equivalent to moving some functional facilities of the station depot to the factory to replace the original on-site operation. Its construction features are "Three Many": many...
Fund from Joint International Research Laboratory of Reproduction and Development,Institute of Life Science,Chongqing Medical University.National Key R&D Program of China[grant numbers 2018YFA0800401 to X.Li];National Natural Science Foundation of China[grant numbers 81770861 and 31571401 to X.Li];Chongqing Science and Technology Foundation[grant number cstc2018jcy-jAX0232];Science and Technology Research Program of Chongqing Municipal Education Commission[grant number KJZD-K201800402];The Outstanding Talent Fund of Chongqing Medical University[grant number BJRC201707];Chongqing education committee[grant number CYB17105].
Adipocytes and immune cells are vital for the development of adipose tissue.Adi-pokines secreted by adipocytes regulate adipogenesis and body metabolism.Chemerin is one of the adipokines.However,the function and mecha...
Oral methadone or sublingual buprenorphine are first-line medications for pharmacotherapy of opioid use disorders(OUDs).Three long-acting buprenorphine depot or implant formulations are currently available for the tre...