DEPOT

作品数:67被引量:39H指数:3
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相关机构:清华大学山东大学同济大学上海医药工业研究院更多>>
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The Impact of Intramuscular Depot Betamethasone Injection (Diprospan) on Patients with Fibromyalgia and Normal C-Reactive Protein Levels
《Open Journal of Rheumatology and Autoimmune Diseases》2024年第4期184-189,共6页George Habib Hani Nijm Uriel Levinger Mohammad Hyder 
Introduction: Intramuscular depot betamethasone treatment had resulted in a significant improvement among fibromyalgia patients with elevated C-reactive protein (C-RP) levels. Here, we wanted to evaluate the same regi...
关键词:FIBROMYALGIA CORTICOSTEROIDS Intramuscular Injection DIPROSPAN C-Reactive Protein 
Nascent mRNA damage:depot and disposal
《Signal Transduction and Targeted Therapy》2024年第9期3546-3547,共2页Mark Helm Marie-Luise Winz 
funded by Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)[project number 439669440 TRR319 RMaP TP C01/C03 to M.H.TP B05 to M.-L.W.].
In a recent study published in Cell,Zhou et al.1 have characterized a highly unusual behavior of specialized stress granules(SG),driven by metabolism of UV-damaged pre-mRNA.These cytoplasmic SGs are characterized by a...
关键词:METABOLISM DAMAGE 
Fat deposition and partitioning for meat production in cattle and sheep
《Animal Nutrition》2024年第2期376-386,共11页Shimin Liu Yanyan Yang Hailing Luo Wenjie Pang Graeme BMartin 
In markets for beef and sheep meat,an appropriate level of intramuscular fat(IMF)is highly desirable for meat-eating quality,but strategies to improve it usually lead to an undesirable excess in carcase fat,presenting...
关键词:Fat depot Fat partition Intramuscular fat Feed efficiency BOVINE OVINE 
Combination of AAV-delivered tumor suppressor PTEN with anti-PD-1 loaded depot gel for enhanced antitumor immunity
《Acta Pharmaceutica Sinica B》2024年第1期350-364,共15页Yongshun Zhang Lan Yang Yangsen Ou Rui Hu Guangsheng Du Shuang Luo Fuhua Wu Hairui Wang Zhiqiang Xie Yu Zhang Chunting He Cheng Ma Tao Gong Ling Zhang Zhirong Zhang Xun Sun 
This study was supported by National Natural Science Foundation of China(Grant Nos.81925036,China);the Key Research and Development Program of Science and Technology Department of Sichuan Province(Grant No.2020YFS0570,China);111 project(Grant No.B18035,China).
Recent clinical studies have shown that mutation of phosphatase and tensin homolog deleted on chromosome 10(PTEN)gene in cancer cells may be associated with immunosuppressive tumor microenvironment(TME)and poor respon...
关键词:Triple therapy Adeno-associated virus PTEN PPSG@anti-PD-1 CpG Immunogenic cell death Antitumor immune response Immune memory 
Real-world effectiveness and safety of goserelin 10.8-mg depot in Chinese patients with localized or locally advanced prostate cancer
《Cancer Biology & Medicine》2023年第12期1047-1059,共13页Nanhui Chen Zengjun Wang Ming Chen Qi Ma Yi He Yujie Wang Xin Li Mingxing Qiu Lei Shi Shaoxing Zhu Qun Xie Xiuheng Liu Benkang Shi Guowen Lin Weizhong Yang Yongbin Liao Haibin Zhang Shusheng Wang Jiexian Li Shaogang Wang Lijun Dong Hui Chen Jiaju Lu YongyiCheng Xiaoping Zhang Lulin Ma Liqun Zhou He Wang Shen Li Dingwei Ye 
Objective:Real-word data on long-acting luteinizing hormone-releasing hormone(LHRH)agonists in Chinese patients with prostate cancer are limited.This study aimed to determine the real-world effectiveness and safety of...
关键词:GOSERELIN hormone-sensitive luteinizing hormone-releasing hormone prostate cancer China real-world 
Supramolecular approaches for insulin stabilization without prolonged duration of action
《Acta Pharmaceutica Sinica B》2023年第5期2281-2290,共10页Rolande Meudom Yanxian Zhang Michael A.VandenBerg Lei Zou Yi Wolf Zhang Matthew J.Webber Danny Hung-Chieh Chou 
NIDDK(DK120430,DK121336,USA)to Danny Hung-Chieh Chou;JDRF(5-CDA-2020-947-A-N,USA)to Matthew J.Webber。
Aggregation represents a significant challenge for the long-term formulation stability of insulin therapeutics.The supramolecular PEGylation of insulin with conjugates of cucurbit[7]uril and polyethylene glycol(CB[7]-...
关键词:Diabetes mellitus Insulin aggregation Supramolecular PEGylation Selective N-Terminal modification N-terminal acid-modified insulin Subcutaneous depot HYPOGLYCEMIA Subcutaneous administration 
A self-activated NO-releasing hydrogel depot for photothermal enhanced sterilization被引量:2
《Nano Research》2023年第4期5346-5356,共11页Shen Zhang Kelei Guan Yaoxin Zhang Junqing Zhang Hongyu Fu Ting Wu Dilan Ouyang Chaoqun Liu Qiang Wu Zhaowei Chen 
Financial support was provided by the National Key Research and Development Program of China(No.2020YFA0210800);the Key Technologies R&D Program of Henan(No.212102310231);the Academic Key Research Projects of Henan(Nos.21A430006 and 22A310010);the Major Project of Science and Technology of Fujian Province(No.2020HZ06006);the National Natural Science Foundation of China(Nos.22277011 and 22107019).
The ascendant danger of bacterial infections has resulted in an urgent requirement for developing new antibacterial approaches.Recently,nitric oxide(NO)has shown a broad-spectrum antimicrobial activity while avoiding ...
关键词:bacterial infections nitric oxide HYDROGEL PHOTOTHERMAL antibacterial 
A Brief Analysis of Improving Project Safety and Efficiency with “Three Hua” Control as the Starting Point
《外文科技期刊数据库(文摘版)工程技术》2021年第10期0923-0926,共6页WANG Shengguo 
The "Five Hua" operation of skid block is equivalent to moving some functional facilities of the station depot to the factory to replace the original on-site operation. Its construction features are "Three Many": many...
关键词:DEPOT functional facilities Three Hua control skid operation 
Chemerin deficiency regulates adipogenesis is depot different through TIMP1被引量:4
《Genes & Diseases》2021年第5期698-708,共11页Cheng-Long Huang Liu-Ling Xiao Min Xu Jun Li Shu-Fen Li Cui-Song Zhu Yu-Li Lin Rui He Xi Li 
Fund from Joint International Research Laboratory of Reproduction and Development,Institute of Life Science,Chongqing Medical University.National Key R&D Program of China[grant numbers 2018YFA0800401 to X.Li];National Natural Science Foundation of China[grant numbers 81770861 and 31571401 to X.Li];Chongqing Science and Technology Foundation[grant number cstc2018jcy-jAX0232];Science and Technology Research Program of Chongqing Municipal Education Commission[grant number KJZD-K201800402];The Outstanding Talent Fund of Chongqing Medical University[grant number BJRC201707];Chongqing education committee[grant number CYB17105].
Adipocytes and immune cells are vital for the development of adipose tissue.Adi-pokines secreted by adipocytes regulate adipogenesis and body metabolism.Chemerin is one of the adipokines.However,the function and mecha...
关键词:ADIPOGENESIS Adipose tissue depot CHEMERIN INFLAMMATION TIMP1 
Recent advances in the treatment of opioid use disorders–focus on long-acting buprenorphine formulations被引量:1
《World Journal of Psychiatry》2021年第9期543-552,共10页Michael Soyka Andreas G Franke 
Oral methadone or sublingual buprenorphine are first-line medications for pharmacotherapy of opioid use disorders(OUDs).Three long-acting buprenorphine depot or implant formulations are currently available for the tre...
关键词:OPIOIDS Opioid dependence Maintenance treatment METHADONE BUPRENORPHINE DEPOT Implant 
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