LINARIN

作品数：4被引量：15H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Chinese Herbal Medicines》《Digital Chinese Medicine》《Journal of Pharmaceutical Analysis》更多>>
相关基金：河南省自然科学基金中国博士后科学基金国家自然科学基金更多>>
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Preparation and pharmacokinetics in vivo of linarin solid dispersion and liposome
《Chinese Herbal Medicines》2022年第2期310-316,共7页Yingying Huang Lihua Xu Fangping Zhang Yang Liu Yunyu Wang Fangfeng Meng Shuang Li Xintao Cheng Yuefeng Bi 
financed by Natural Science Foundation of Henan Province(Grant No.182300410348)。
Objective:The current investigation aimed to determine the appropriate dosage form by comparing solid dispersion and liposome to achieve the purpose of improving the solubility and bioavailability of linarin.Methods:L...
关键词：BIOAVAILABILITY intestinal absorption LINARIN LIPOSOME PHARMACOKINETICS solid dispersion 
Anti-diabetic effects of linarin from Chrysanthemi Indici Flos via AMPK activation被引量：5
《Chinese Herbal Medicines》2022年第1期97-103,共7页Zhenji Wang Zhe Bai Jinghua Yan Tengteng Liu Yingmei Li Jiahui Xu Xiaoqian Meng Yuefeng Bi 
supported by the National Natural Science Foundation of China (grant numbers 81273392);the Natural Science Foundation of Henan Province (grant numbers 182300410348)
Objective:The purpose of this study is to investigate the anti-diabetic effects of linarin,a flavonoid extracted from Chrysanthemi Indici Flos(CIF),and its potential mechanisms.Methods:The effects of linarin on cell v...
关键词：AMPK anti-diabetes Chrysanthemi Indici Flos insulin resistance LINARIN type 2 diabetes 
Linarin ameliorates innate inflammatory response in an experimental dry eye model via modulation of the NLRP3 inflammasome被引量：8
《Digital Chinese Medicine》2021年第1期42-53,共12页CHEN Mei LI Jie PENG Jun HUANG Yu OUYANG Weiji LIU Xiaoqing SHEN Zhibin LI Changdong WANG Yi PENG Qinghua 
funding support from the China Postdoctoral Science Foundation Grant (No. 2018M632973);Sichuan Science and Technology Program (No. 2018JY0388);the First-Class Open Fund for Integrated Chinese and Western Medicine (No. 2018ZXYJH05);Traditional Chinese Medicine First-Class Discipline Open Fund (No. 2018ZYX57);the Construction Project of the Hunan Engineering Technology Research Center for the Prevention and Treatment of Otorhinolaryngologic Diseases and Protection of Visual Function with Chinese Medicine (No. 2018YGC02 and No. 2018YGC04);the Research and Innovation Project of Graduate Students in Hunan Province (No. CX20190538)
Objective To investigate the effect and mechanism of linarin(LA) in an experimental dry eye model.Methods LA or vehicle was applied in two dry eye models: an in vitro hyperosmotic stress model and an in vivo desiccati...
关键词：LINARIN Dry eye disease NLRP3 inflammasome Ocular surface Innate inflammatory response 
Fingerprint analysis of Cirsium japonicum DC.using high performance liquid chromatography被引量：2
《Journal of Pharmaceutical Analysis》2013年第4期278-284,共7页Hongli Ge Muhetar Turhong Munire Abudkrem Yuhai Tang 
supported by the Main Program of Autonomous Region College Scientific Research Program (XJEDU2008145)
In many areas of China Cirsium setosum is used as Cirsiumjaponicum DC. Although the two herbs have similar appearance and many similar compounds, they are totally different medicinal material, and have different pharm...
关键词：Cirsium japonicum DC FINGERPRINT High performance liquidchromatography-photodio dearray detec-tor （HPLC-PDA） LINARIN 
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