云南高校图书馆联盟文献共享服务平台- TETRAHYDROPYRIDINE

TETRAHYDROPYRIDINE: 作品数：10被引量：14H指数：2; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：陈生弟刘振国陈红专郭明更多>>; 相关机构：汕头大学江南大学上海交通大学医学院附属瑞金医院上海第二医科大学更多>>; 相关期刊：《Chinese Medical Journal》《Medical Bulletin of Shanghai Jiaotong University》《Chemical Research in Chinese Universities》《Neural Regeneration Research》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>

Phosphine-catalyzed [4＋2] Annulations of α-Aminonitriles with Allenoates： Synthesis of Functionalized Tetrahydropyridines: 《Chemical Research in Chinese Universities》2016年第3期385-389,共5页JANG Hochol LIU Wei ZHANG SEAN Xiao'an LIAO Weiwei; Supported by the National Natural Science Foundation of China（No. 21372096）.; Phosphine-catalyzed [4＋2] annulations of 2-（acetoxymethyl）buta-2,3-dienoates with α-aminonitriles have been developed, in which a-aminonitriles serve as C, N-bisnucleophilic reaction partners and 2-（acetoxymethyl...; 关键词：ANNULATION Catalysis TETRAHYDROPYRIDINE

Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mice被引量：7: 《Neural Regeneration Research》2012年第14期1080-1087,共8页Tao Wang Yanyong Liu Nan Yang Chao Ji Piu Chan Pingping Zuo; supported by the grants from National Basic Research Program of China (973 Program), No.2007B507400, 2010CB934002, 2011CB504101, 2011CBA00408;the National Natural Science Foundation of China, No. 81050025;the grant from the Ministry of Science and Technology of China Eleventh 5-year Plan-Technical Platform for Drug Development, No. 2009ZX09303-8; Our previous research showed that octacosanol exerted its protective effects in 6-hydroxydopamine-induced Parkinsonian rats. The goal of this study was to investigate whether octacosanol would attenuate neurotoxicity ...; 关键词：Parkinson＇s disease neuroprotecion mitogen-activated protein kinase c-Jun N-terminal kinase p38MAPK substantia nigra neural regeneration

Isatin decreases Bax protein expression in the substantia nigra of a mouse model of Parkinson's disease被引量：3: 《Neural Regeneration Research》2011年第26期2022-2025,共4页Jiguo Zhang Fang Zhang Yanlong Qiu Wang Yue; a grant from Shandong Provincial Education Department, No. J08LH54; The present study observed the action of 1H-indole-2, 3-dione （isatin） on Bax protein expression in the substantia nigra of a Parkinson＇s disease animal model. Parkinson＇s disease-like behaviors were induced in C5...; 关键词：1H-indole-2 3-dione （isatin） Parkinson＇s disease 1-methyl-4-phenyl-1 2 3 6- tetrahydropyridine Bax MOUSE neurodegenerative disease neural regeneration

Organocatalytically Enantioselective Approach to Polysubsti- tuted Tetrahydropyridines and Piperidines: 《Chinese Journal of Chemistry》2011年第9期1873-1879,共7页Yu, Fang Zhang, Xiaojing Jiang, Yongwen; Project supported by the National Natural Science Foundation of China （No. 20921091）.; A convenient and highly enanfioselecfive method for assembly of functionalized 1,2,3,4,5-pentasubstituted tetrahydropyridines and piperidines was developed. This method relies on preparing the required enantiopure cyc...; 关键词：ORGANOCATALYSIS Michael addition reductive amination substituted piperidine TETRAHYDROPYRIDINE

Synthesis and Bioactivity of Arecoline Derivatives Containing Amino-s-triazole Coupled Oxadiazole被引量：1: 《Chinese Chemical Letters》2006年第1期19-22,共4页Guo Qiang HU Sheng LI Wen Long HUANG Hai WANG; supported by the State Basic Research and Development Project(No.G 1998051112);the Science Foundation of Henan University(04ZDZR009).; 5-（5＂-Substituted phenyl-[1＂,3＂,4＂]oxadiazol-2＂-yl methylsulfanyl）-3-pyridin-3′-yl- [1,2,4] triazol-4-yl amines la-j were quaternarized with methyl iodide to afford the corresponding methyl pyridinium salts 2a...; 关键词：TETRAHYDROPYRIDINE triazolylamine OXADIAZOLE muscarinic agonist vascular activity.

Synthesis of Tetrahydropyridinyltriazolothiadiazines as Possible Muscarinic Agonists: 《Chinese Chemical Letters》2005年第1期1-3,共3页GuoQiangHU WenLongHUANG HaiWANG; supported by the State Basic Research and Development Project(No.G1998051112);the Science Foundation of Henan University(XK02041); Amino-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol 1 were condensed with 2-bromo-1- (substituted phenyl)ethanone to give pyridinyltriazolothiadiazines 2a^c, which were quaternarized with methyl iodide and oxidized wit...; 关键词：TETRAHYDROPYRIDINE triazolothiadiazine muscarinic agonist vascular activity.

Synthesis of 2-and 5-(1,1-Dimethyl-1,2,5,6-tetrahydropyridinium-3-yl)oxadiazoline Iodides被引量：1: 《Chinese Journal of Chemistry》2002年第10期1115-1120,共6页胡国强黄文龙张惠斌黄胜堂汪海; ProjectsupportedbytheMajorStateBasicResearchDevelopmentProgramofChina (No.19980 5 1112 ); A series of 2- and 5-(1,1-dimethyl-1,2,5,6-tetrahydropyridinium-3-yl)oxadiazoline iodides, which might be used as M 1 muscarinic receptor agonists, was synthesized from nicotin-aldehyde and nicotinhydrazine, respecti...; 关键词：TETRAHYDROPYRIDINE oxadiazoline muscarinic receptor agonist synthesis

Synthesis and Crystal Structure of Ethyl 4-(3,4-Methylenedioxylphenyl)-6-methyl-2-oxo-l,2,3,4-tetrahydropyridine-5-carboxylate under Microwave Irradiation: 《Chinese Journal of Structural Chemistry》2002年第6期609-612,共4页TUShu－Jiang GAOYuan 等; Supported by the Natural Science Foundation of Jiangsu province(No.BK2001142);the Natural Science Foundation of Jiangsu Education Department(No.01KJB150008); The crystal structure of the title compound (C16H17NO5) has been determined by single-crystal X-ray diffraction. The crystal is of monoclinic, space group C2/c with a = 18.520(2), b = 7.8910(1), c = 21.728(3) A, β = ...; 关键词：1 4-DIHYDROPYRIDINE synthesis microwave irradiation crystal structure

Eldepryl prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigral neuronal apoptosis in mice被引量：2: 《Chinese Medical Journal》2001年第3期16-19,102-103,共6页郭明陈生弟刘振国陈红专; Objective To study the apoptotic effects of 1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine (MPTP) on the nigral dopaminergic neurons of mice and 1 methyl 4 phenylpyridium ion (MPP +) on pheochromocytoma (P...; 关键词：methyl 4 phenyl 1 2 3 6 tetrahydropyridine · 1 methyl 4 phenylpyridium ion · Eldepryl · nigral dopaminergic neuron · PC12 cell · apoptosis · Parkinson's disease

THE EFFECTS OF DEPRENYL AND 1-METHYL-4-PHENYL-1, 2, 3, 6-TETRAHYDROPYRIDINE (MPTP) ON 2-DEOXYGLUCOSE UPTAKE IN THE MOUSE BRAIN: 《Medical Bulletin of Shanghai Jiaotong University》1992年第1期70-74,共5页陈生弟徐德隆周孝达钱可久; ~3H-2-deoxyglucose (2-DG) autoradiographic technique was used to study the ef feets of a monoamine-oxidase-B (MAO-B) inhibitor deprenyl and the neurotoxin Ⅰ-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) on 2-D...; 关键词：~3H-2-deoxyglucose autoradiography DEPRENYL 1-methyl-4-phenyl-1 2 3 6—tetrahydropyridine

TETRAHYDROPYRIDINE