KYOTO

作品数：109被引量：213H指数：7
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  • 期刊=Neural Regeneration Researchx
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RNA sequencing of exosomes secreted by fibroblast and Schwann cells elucidates mechanisms underlying peripheral nerve regeneration被引量：4
《Neural Regeneration Research》2024年第8期1812-1821,共10页Xinyang Zhou Yehua Lv Huimin Xie Yan Li Chang Liu Mengru Zheng Ronghua Wu Songlin Zhou Xiaosong Gu Jingjing Li Daguo Mi 
supported by the National Natural Science Foundation of China,No.81870975(to SZ)。
Exosomes exhibit complex biological functions and mediate a variety of biological processes,such as promoting axonal regeneration and functional recove ry after injury.Long non-coding RNAs(IncRNAs)have been reported t...
关键词：ceRNA network EXOSOMES fibroblast cells Gene Ontology(GO) Kyoto Encyclopedia of Genes and Genomes(KEGG) protein-protein interaction(PPI)networks RNA-seq Schwann cells 
Transcriptomic and bioinformatics analysis of the mechanism by which erythropoietin promotes recovery from traumatic brain injury in mice被引量：1
《Neural Regeneration Research》2024年第1期171-179,共9页Weilin Tan Jun Ma Jiayuanyuan Fu Biying Wu Ziyu Zhu Xuekang Huang Mengran Du Chenrui Wu Ehab Balawi Qiang Zhou Jie Zhang Zhengbu Liao 
supported by the National Natural Science Foundation of China,No.81771355;the Natural Science Foundation of Chongqing Science and Technology Bureau,Nos.CSTC2015jcyjA10096,cstc2021jcyj-msxmX0262(all to ZL)。
Recent studies have found that erythropoietin promotes the recovery of neurological function after traumatic brain injury.However,the precise mechanism of action remains unclea r.In this study,we induced moderate trau...
关键词：axon guidance bioinformatics analysis competing endogenous RNA ERYTHROPOIETIN Gene Ontology Kyoto Encyclopedia of Genes and Genomes non-coding RNA RNA sequencing transcriptomics traumatic brain injury 
Bioinformatics analysis of ferroptosis in spinal cord injury被引量：13
《Neural Regeneration Research》2023年第3期626-633,共8页Jin-Ze Li Bao-You Fan Tao Sun Xiao-Xiong Wang Jun-Jin Li Jian-Ping Zhang Guang-Jin Gu Wen-Yuan Shen De-Rong Liu Zhi-Jian Wei Shi-Qing Feng 
supported by National Key Research and Development Project of Stem Cell and Transformation Research,No.2019YFA0112100;Tianjin Key Research and Development Plan,Key Projects for Science and Technology Support,No.19YFZCSY00660(both to SQF)。
Ferroptosis plays a key role in aggravating the progression of spinal cord injury(SCI),but the specific mechanism remains unknown.In this study,we constructed a rat model of T10 SCI using a modified Allen method.We id...
关键词：bioinformatics drug ferroptosis Gene Ontology enrichment analysis gene-miRNA network Kyoto Encyclopedia of Genes and Genomes pathway mRNA-miRNA-lncRNA network progression spinal cord injury 
Expression and regulatory network of long noncoding RNA in rats after spinal cord hemisection injury被引量：2
《Neural Regeneration Research》2022年第10期2300-2304,共5页Wei Liu Jin-Cheng Tao Sheng-Ze Zhu Chao-Lun Dai Ya-Xian Wang Bin Yu Chun Yao Yu-Yu Sun 
Long noncoding RNAs(lncRNAs)participate in a variety of biological processes and diseases.However,the expression and function of lncRNAs after spinal cord injury has not been extensively analyzed.In this study of righ...
关键词：bioinformatic analysis biological process gene ontology analysis inflammatory response Kyoto encyclopedia of genes and genomes analysis long noncoding RNAs regulatory network RNA sequencing spinal cord injury synaptic transmission 
Gene and protein expression profiles of olfactory ensheathing cells from olfactory bulb versus olfactory mucosa被引量：1
《Neural Regeneration Research》2022年第2期440-449,共10页Yuan-Xiang Lan Ping Yang Zhong Zeng Neeraj Yadav Li-Jian Zhang Li-Bin Wang He-Chun Xia 
supported by Key Research Projects of Ningxia Hui Autonomous Region of China,No.2018BCG01002(to HCX);the Natural Science Foundation of Ningxia Hui Autonomous Region of China,No.NZ17150(to PY)。
Olfactory ensheathing cells(OECs) from the olfactory bulb(OB) and the olfactory mucosa(OM) have the capacity to repair nerve injury. However, the difference in the therapeutic effect between OB-derived OECs and OM-der...
关键词：biological process cellular component GENE Gene Ontology Kyoto Encyclopedia of Genes and Genomes molecular function olfactory bulb olfactory ensheathing cells olfactory mucosa PROTEIN 
Bioinformatic analysis of cytokine expression in the proximal and distal nerve stumps after peripheral nerve injury被引量：1
《Neural Regeneration Research》2021年第5期878-884,共7页Xiao-Qing Cheng Wen-Jing Xu Xiao Ding Gong-Hai Han Shuai Wei Ping Liu Hao-Ye Meng Ai-Jia Shang Yu Wang Ai-Yuan Wang 
This study was supported by the National Natural Science Foundation of China,No.31771052(to YW);the National Key R&D Program of China,No.2017YFA0104702(to AJS);the Youth Cultivation Project of Military Medical Science,No.16QNP144(to YW).
In our previous study,we investigated the dynamic expression of cytokines in the distal nerve stumps after peripheral nerve injury using microarray analysis,which can characterize the dynamic expression of proteins.In...
关键词：cytokine distal stumps Gene Ontology Kyoto Encyclopedia of Genes and Genomes Pathway microarray microenvironment peripheral nerve injury proximal stumps 
Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validation被引量：7
《Neural Regeneration Research》2020年第12期2262-2269,共8页Yun-Liang Tang Long-Jun Fang Ling-Yang Zhong Jian Jiang Xiao-Yang Dong Zhen Feng 
supported by the National Natural Science Foundation of China,Nos.81860409(to ZF),81660382(to ZF);Graduate Students Innovation Fund Project in Jiangxi Province of China,No.YC2019-B036(to YLT)。
The exact mechanisms associated with secondary brain damage following traumatic brain injury(TBI)remain unclear;therefore,identifying the critical molecular mechanisms involved in TBI is essential.The m RNA expression...
关键词：bioinformatics DEGs differentially expressed genes Gene Ontology hub genes inflammation Kyoto Encyclopedia of Genes and Genomes molecular mechanism traumatic brain injury 
Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection被引量：3
《Neural Regeneration Research》2020年第3期503-511,共9页Xiao-Qing Cheng Xue-Zhen Liang Shuai Wei Xiao Ding Gong-Hai Han Ping Liu Xun Sun Qi Quan He Tang Qing Zhao Ai-Jia Shang Jiang Peng 
supported by the National Key Research&Development Program of China,No.2017YFA0104702(to AJS);the National Basic Research Program of China(973 Program),No.2014CB542201(to JP)
A large number of chemokines,cytokines,other trophic factors and the extracellular matrix molecules form a favorable microenvironment for peripheral nerve regeneration.This microenvironment is one of the major factors...
关键词：cytokines DISTAL stump gene ontology KYOTO ENCYCLOPEDIA of Genes and Genomes pathway peripheral nerve injury protein microarray PROTEIN-PROTEIN interaction network Wallerian degeneration 
Spatiotemporal microRNA profile in peripheral nerve regeneration:miR-138 targets vimentin and inhibits Schwann cell migration and proliferation被引量：6
《Neural Regeneration Research》2018年第7期1253-1262,共10页Travis B.Sullivan Litchfield C.Robert Patrick A.Teebagy Shannon E.Morgan Evan W.Beatty Bryan J.Cicuto Peter K.Nowd Kimberly M.Rieger-Christ David J.Bryan 
supported by the Leisa V.Clayton Foundation
While the peripheral nervous system has regenerative ability,restoration of sufficient function remains a challenge.Vimentin has been shown to be localized in axonal growth fronts and associated with nerve regeneratio...
关键词：non-coding RNA neural regeneration nerve guide sciatic nerve transection peripheral nerve injury wound healing Gene Ontology processes Kyoto Encyclopedia of Genes and Genomes pathways microarray luciferase assay 
Modulation of valosin-containing protein by Kyoto University Substances(KUS) as a novel therapeutic strategy for ischemic neuronal diseases被引量：1
《Neural Regeneration Research》2017年第8期1252-1255,共4页Masayuki Hata Hanako Ohashi Ikeda 
supported in part by research grants from the Astellas Foundation for Research on Metabolic Disorders,the Japan Foundation for Applied Enzymology,the Uehara Memorial Foundation,Mochida Memorial Foundation for Medical and Pharmaceutical Research,YOKOYAMA Foundation for Clinical Pharmacology(YRY1308);Japan Intractable Diseases Research Foundation,Japan Research Foundation for Clinical Pharmacology,ONO Medical Research Foundation,Takeda Science Foundation,Japan National Society for the Prevention of Blindness,a Grant-in-Aid for Young Scientists(24791850,to IHO;15K20255,to HM);the Ministry of Education,Culture,Sports,Science,and Technology of Japan(to IHO);the Ministry of Health,Labour and Welfare of Japan(to IHO)
Retinal ischemia causes several vision-threatening diseases, including diabetic retinopathy, retinal artery occlusion, and retinal vein occlusion. Intracellular adenosine triphosphate（ATP） depletion and subsequent i...
关键词：adenosine triphosphatase C/EBP homologous protein central retinal artery occlusion endoplasmicreticulum stress neuroprotective therapy retinal ganglion cell 
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